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Protein Overview: vhp-1

General Information:
Name(s) found: vhp-1 / CE27919 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00006923 locus:vhp-1 Tyrosine-protein phosphatase vhp-1 status:Confirmed UniProt:Q10038 protein_id:CCD68974.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 606 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISSLink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    Biological Process: inactivation of MAPK activity [IDALink to PubMed article][IGILink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    protein amino acid dephosphorylation [IDALink to PubMed article][IEALink to PubMed article]
    response to copper ion [IGILink to PubMed article]
    negative regulation of JNK cascade [IDALink to PubMed article]
    dephosphorylation [IEALink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed article]
    Molecular Function: protein tyrosine phosphatase activity [IEALink to PubMed article]
    phosphatase activity [IEALink to PubMed article]
    JUN kinase phosphatase activity [IDALink to PubMed article]
    MAP kinase tyrosine/serine/threonine phosphatase activity [IDALink to PubMed article]
    protein tyrosine/serine/threonine phosphatase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGQPFEAFR KNRKRKKTKN KKKRRNNNNS KNKTPNTFPN EIEEQDPVSS LPTFPAKKFG  60
   61 LKLQLTLTSS PTNSSSPISS SSPTNGGFKQ FAQQYPQLCE SSEGMTRLPQ SLSQPCLSQP 120
  121 TGDGITLITP NIYLGSQIDS LDETMLDALD ISVVINLSMT CPKSVCIKED KNFMRIPVND 180
  181 SYQEKLSPYF PMAYEFLEKC RRAGKKCLIH CLAGISRSPT LAISYIMRYM KMGSDDAYRY 240
  241 VKERRPSISP NFNFMGQLLE YENVLIKDHV LDYNQASRPH RHMDYYGPSD LCPPKVPKSA 300
  301 SSNCVFPGST HDESSPSSPS VSEGSAASEP ETSSSAASSS STASAPPSMP STSEQGTSSG 360
  361 TVNVNGKRNM TMDLGLPHRP KALGLPSRIG TSVAELPSPS TELSRLSFNG PEAIAPSTPI 420
  421 LNFTNPCFNS PIIPVASSSR EVILTLPTPA ASSSSSTSSE PSFDFSSFES SSSSSIVVEN 480
  481 PFFASTEVPA GSSSISTPSG SQSTPASASS SAASRCRMKG FFKVFSKKAP ASTSTPASST 540
  541 PGTSRAARPE CLRSSGIIIS APVLAITEEE DAESPESGFN EPEVGEEDDD SVSICSTSSL 600
  601 EIPCHQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..120] PSI-BLAST 22.69897 No description for 2oucA was found.
    2 View Details [121..318] PSI-BLAST 42.0 No description for 2g6zA was found.
    3 View Details [319..410] deduced N/A No confident structure predictions are available.
    4 View Details [411..606] MSA 11.198995 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle