YRC Public Data Repository - Protein Structure Prediction

Protein:	SLM2
Organism:	Saccharomyces cerevisiae
Length:	656 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLM2.

Description	E-value	Query Range	Subject Range
SLM1_YEAST - Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1 OS=Saccharomyces cerevisiae (strain ATCC ... gi\|190406316 - gi\|190406316\|gb\|EDV09583.1\| hypothetical protein SCRG_05277 [Saccharomyces cerevisiae RM11-1a] gi\|207344373 - gi\|207344373\|gb\|EDZ71539.1\| YIL105Cp-like protein [Saccharomyces cerevisiae AWRI1631] SLM1 - Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in ...	563.0	[0..14]	[645..25]
gi\|49644390 - gi\|49644390\|emb\|CAG97962.1\| KLLA0F03839p [Kluyveromyces lactis] gi\|49644390, gi\|... - gi\|50310469\|ref\|XP_455254.1\| unnamed protein product [Kluyveromyces lactis], gi\|49644390\|emb\|CAG9796...	357.0	[0..1]	[625..1]
gi\|44982377 - gi\|44982377\|gb\|AAS51686.1\| ADL234Cp [Ashbya gossypii ATCC 10895] gi\|44982377, gi\|... - gi\|45187639\|ref\|NP_983862.1\| ADL234Cp [Ashbya gossypii ATCC 10895], gi\|44982377\|gb\|AAS51686.1\| ADL23...	350.0	[0..137]	[571..219]
SLM1_SCHPO - Cytoskeletal signaling protein slm1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=slm1 P... SPAC637.13c - cytoskeletal signaling protein	331.0	[0..166]	[649..36]
gi\|49525794, gi\|... - gi\|50288115\|ref\|XP_446486.1\| unnamed protein product [Candida glabrata], gi\|49525794\|emb\|CAG59413.1\|... gi\|49525794 - gi\|49525794\|emb\|CAG59413.1\| unnamed protein product [Candida glabrata]	298.0	[0..119]	[634..188]
gi\|108995611 - gi\|108995611\|ref\|XP_001093292.1\| PREDICTED: similar to centaurin, beta 5 [Macaca mulatta]	284.0	[0..189]	[615..115]
ACAP3 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	276.0	[0..189]	[615..19]
gi\|114591214 - gi\|114591214\|ref\|XP_516962.2\| PREDICTED: centaurin, beta 2 [Pan troglodytes]	276.0	[0..189]	[612..207]

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Predicted Domain #1

Region A:
Residues: [1-121]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYQRNSARA SLDLRSQYQQ LEGRMRSEHF NPAYQQQQQK GQNIPLSLPS SLAQRNPIPY  60
   61 PIDAVTSDPT IPAQLNVYDH DRQNSIVDAA AGTNTTHSLN SNNIPSSQNN NINNNNINNV 120
  121 G

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [122-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFTDPSMLTL PKMSLHSHQK QYDSNQNDPR SPLAILIPTS AQPTDVLSAR FSAWRNVIRA  60
   61 ILVYLSETAS IQDEIVRQQL RLSHAVQFPF FSIENQYQPV SNEDKSMQKF FLPLGSGSVQ 120
  121 DLPTMLTKYH DNLASLASKS SKELTSEIIP RLEDLRRDLL VKIKEIKA

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	8.2
Match:
Description:	No description for 1i84S was found.

Predicted Domain #3

Region A:
Residues: [290-404]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQSDFKNSCN KELQQTKHLM KLFNESLKEC KLGTPKSDPF LIKLQLEKQI KRQLVEENYL  60
   61 HEAFDNLQNS GAQLESVIVM EIQNGLTSYA RILGKEAQVV FDSVISKLDS TILNK

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	8.2
Match:
Description:	No description for 1i84S was found.

Predicted Domain #4

Region A:
Residues: [405-595]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTNLEWDSFI LRNISNFVPP NLPMRRFKEI SYSNQNDPFT FEVKSGFLEK RSKFLKSYSR  60
   61 GFYVLTPSFL HEFKTPDKHK FSTPLMSIPL VECTVTEHSK KTKSNSEQGK NKFILRTNSN 120
  121 GLIHRGHNWV FKVDSYDDMI EWFGNIKALS SLPNYDDKCK YVSKVAKLSK EKAKSNENTT 180
  181 ESVTPQVTNE Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.594777
Match:	1fhwA
Description:	Grp1
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [596-656]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HTRYDDVSSS NFPLNSIPKL DNLTITNTTS SIPETNDSQI QNRVPEFYIE NVDSPRKSNQ  60
   61 L

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits