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View Structure Prediction Details

Protein: YME2
Organism: Saccharomyces cerevisiae
Length: 850 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YME2.

Description E-value Query
Range
Subject
Range
SPBC83.05 - mitochondrial RNA-binding protein
YME2_SCHPO - Mitochondrial escape protein 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=yme2 PE=3 S...
0.0 [59..850] [32..767]
YME2_YEAST - Mitochondrial escape protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YME2 PE=1...
YME2 - Integral inner mitochondrial membrane protein with a role in maintaining mitochondrial nucleoid stru...
0.0 [1..850] [1..850]
gi|10444072 - gi|10444072|gb|AAG17696.1| mitochondrial inner membrane protein YME2 [Zygosaccharomyces bailii]
7.0E-30 [43..126] [48..129]

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Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLVRTTSLN VSRMPVPCLA RGIGILKGKY RLANLMNAQP SVRHVSSEIQ QKDQQAGESN  60
   61 TATDTGVIHK SDEETLIYFD NVYARTTSVW NPTLWYNLLL RNQSRDAVRE KIRNLASPPN 120
  121 NPIYGLELKS TIPVKRDGGV FATFVVPPKY TKAQVNSLIQ QNTARESSKN LLSYFTRA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.9031259408875 bayes_pls_golite062009
nucleic acid binding 1.49187911603143 bayes_pls_golite062009
protein binding 1.26544376923141 bayes_pls_golite062009
RNA binding 0.772790649151098 bayes_pls_golite062009
mRNA binding 0.0666883120942833 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [179-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAFPVKGSPW IEDLRRLPST TIVIKFQGPA LTEEEIYSLF RRYGTIIDIF PPTAANNNVA  60
   61 KVRYRSFRGA ISAKNCVSGI EIHNTVLHIQ YENIRRGHLV SNFFTNHTRI AIPVLFALLS 120
  121 IFAVLVFDPI REFSIEQKIT HKYSLSWDNK FWKQLKTL

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 9.552842
Match: PF00076
Description: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [337-850]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSSTMTSIKY YWGGPDDNHQ RKHLWEERIE KVNDLKMWLE ENNNTFVVIR GPRGSGKHDL  60
   61 VMQHTLQNRA NVLYLDCDKL IKSRTDPMFL KNAASQLGYF PIFPWIDSVT GVLDLTVQGL 120
  121 TGQKTGLSET KESRFRNMLT TSLMSIRRIA LKNYKAFVST GDGTVNVKEE DYLQQHPEAK 180
  181 PVIVIDRFEG KSEINGFVYK ELSDWAAMLV QMNIAHVIFL TETVASNQRL SESLPNQVFK 240
  241 NLILSDASKE NSRNYVLSQL EDYLYYNKKS KGENVKEPES EKETAENNDS DSEADTSVKK 300
  301 AEVILNEKEL QEIDASLEPL GGRMLDLQAF VRRVKSGEEP SEAVDKMIEQ ASEQITQMFL 360
  361 SDKIDSNKSA QAWELIELLS ANPVIPFHEI VNKPLFKAAP ETGIMELENN GLITVSRDRG 420
  421 VLQEIRPAKP LYRAAFTYLI NDPELAKVLK TRYLLKVVGF ETGRIKKWEE ELKPLGKVPD 480
  481 QKLFKTRLDY LSGKINASNA VITKCEEEIK NLSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [636-850]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAEVILNEKE LQEIDASLEP LGGRMLDLQA FVRRVKSGEE PSEAVDKMIE QASEQITQMF  60
   61 LSDKIDSNKS AQAWELIELL SANPVIPFHE IVNKPLFKAA PETGIMELEN NGLITVSRDR 120
  121 GVLQEIRPAK PLYRAAFTYL INDPELAKVL KTRYLLKVVG FETGRIKKWE EELKPLGKVP 180
  181 DQKLFKTRLD YLSGKINASN AVITKCEEEI KNLSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle