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View Structure Prediction Details

Protein: TPS3
Organism: Saccharomyces cerevisiae
Length: 1054 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPS3.

Description E-value Query
Range
Subject
Range
gi|173198 - gi|173198|gb|AAA35224.1| ORF4
0.0 [1..1054] [1..1054]
gi|25347119, gi|... - pir||C96703 hypothetical protein T23K23.13 [imported] - Arabidopsis thaliana, gi|12324075|gb|AAG5200...
0.0 [288..1053] [40..839]
gi|8131926 - gi|8131926|gb|AAF73139.1|AF148854_1 trehalose phosphate synthase subunit [Pichia angusta]
0.0 [1..1054] [1..1028]
gi|19568935 - gi|19568935|gb|AAL91978.1|AF483209_1 putative trehalose synthase [Solanum tuberosum]
0.0 [291..1054] [49..842]
gi|113533672, gi... - gi|34910846|ref|NP_916770.1| putative trehalose-6-phosphate synthase [Oryza sativa (japonica cultiva...
0.0 [240..1054] [31..858]

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Predicted Domain #1
Region A:
Residues: [1-250]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIIVASLFL PYTPQFEADV TNSDTAKLVE SSMIKVDCNN QELSNNKQER SSSVTSASSH  60
   61 YIGLPQEAQI NGEPLQRANV GSPATGVNYH NEMEMLSSEQ FLEELTANAT HAANSGIPPA 120
  121 NNPVSSGSTA QRPSVEEFFS APSARVCSPS QEASASSISA SRSSAHHNDL SSSLMKNPNL 180
  181 SFDSHPPRVR SSSKSAVITP VSKSVPDVDP AVVDVAKVRE EFQQQASLPS MKRVSGSTAG 240
  241 DSSIASSSSN 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [251-775]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRYSQQFQDN FIEDTDSEDD IDSDLETDAT KKYNVPKFGG YSNNAKLRAS LMRNSYELFK  60
   61 HLPWTIVDSD KGNGSLKNAV NIAVAEKTVK EPVSWVGTMG IPTDELPHEV CHKISKKLEQ 120
  121 DFSSFPVVTD DITFKGAYKN YAKQILWPTL HYQIPDNPNS KAFEDHSWDY YQKVNQKFSD 180
  181 RIVSVYKPGD TIWIHDYHLM LVPQMVREKL PKAKIGFFLH VSFPSSEVFR CLANRERILE 240
  241 GIIGANFVGF QTKEYKRHFL QTCNRLLAAD VSNDEVKYHC NIVSVMYAPI GIDYYHLTSQ 300
  301 LRNGSVLEWR QLIKERWRNK KLIVCRDQFD RIRGLQKKML AYERFLIENP EYIEKVVLIQ 360
  361 ICIGKSSDPE YERQIMVVVD RINSLSSNIS ISQPVVFLHQ DLDFAQYLAL NCEADVFLVD 420
  421 ALREGMNLTC HEFIVSSFEK NAPLLLSEFT GSSSVLKEGA ILINPWDINH VAQSIKRSLE 480
  481 MSPEEKRRRW KKLFKSVIEH DSDNWITKCF EYINNAWESN QETST

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 254.356547
Match: PF00982
Description: Glycosyltransferase family 20

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [776-1054]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VFNLAPEKFC ADYKASKKHL FIFKISEPPT SRMLSLLSEL SSNNIVYVLS SFTKNTFESL  60
   61 YNGVLNIGLI AENGAYVRVN GSWYNIVEEL DWMKEVAKIF DEKVERLPGS YYKIADSMIR 120
  121 FHTENADDQD RVPTVIGEAI THINTLFDDR DIHAYVHKDI VFVQQTGLAL AAAEFLMKFY 180
  181 NSGVSPTDNS RISLSRTSSS MSVGNNKKHF QNQVDFVCVS GSTSPIIEPL FKLVKQEVEK 240
  241 NNLKFGYTIL YGSSRSTYAK EHINGVNELF TILHDLTAA

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 71.920819
Match: PF02358
Description: Trehalose-phosphatase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity 11.2045941324603 bayes_pls_golite062009
glucosyltransferase activity 8.25064561355471 bayes_pls_golite062009
UDP-glucosyltransferase activity 8.0463972704113 bayes_pls_golite062009
trehalose-phosphatase activity 7.58500038184065 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 3.70184884300914 bayes_pls_golite062009
catalytic activity 2.65148466065976 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.62403914335522 bayes_pls_golite062009
transferase activity 2.18054407163329 bayes_pls_golite062009
UDP-glycosyltransferase activity 2.13085705769565 bayes_pls_golite062009
carbohydrate phosphatase activity 0.78952375993773 bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity 0.690032302126686 bayes_pls_golite062009
glycogen phosphorylase activity 0.607220464589157 bayes_pls_golite062009
binding 0.345236672370351 bayes_pls_golite062009
phosphorylase activity 0.296436712681472 bayes_pls_golite062009
mannosyltransferase activity 0.253888301381021 bayes_pls_golite062009
protein binding 0.198267161626932 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [779-1054]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LAPEKFCADY KASKKHLFIF KISEPPTSRM LSLLSELSSN NIVYVLSSFT KNTFESLYNG  60
   61 VLNIGLIAEN GAYVRVNGSW YNIVEELDWM KEVAKIFDEK VERLPGSYYK IADSMIRFHT 120
  121 ENADDQDRVP TVIGEAITHI NTLFDDRDIH AYVHKDIVFV QQTGLALAAA EFLMKFYNSG 180
  181 VSPTDNSRIS LSRTSSSMSV GNNKKHFQNQ VDFVCVSGST SPIIEPLFKL VKQEVEKNNL 240
  241 KFGYTILYGS SRSTYAKEHI NGVNELFTIL HDLTAA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.09691
Match: 1u02A
Description: Crystal structure of trehalose-6-phosphate phosphatase related protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
trehalose-phosphatase activity 3.78859922218487 bayes_pls_golite062009
transporter activity 2.28749015584769 bayes_pls_golite062009
hydrolase activity 2.23636068759523 bayes_pls_golite062009
transmembrane transporter activity 2.17051010073814 bayes_pls_golite062009
substrate-specific transporter activity 2.14633664297706 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.05684652641195 bayes_pls_golite062009
ion transmembrane transporter activity 2.05060633349756 bayes_pls_golite062009
cation transmembrane transporter activity 1.84740904871745 bayes_pls_golite062009
catalytic activity 1.55296860681783 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 1.53201151596704 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.45647470429539 bayes_pls_golite062009
ATPase activity, coupled 1.44542004757594 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.42792997211574 bayes_pls_golite062009
ATPase activity 1.40341876769691 bayes_pls_golite062009
pyrophosphatase activity 1.352553895791 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 1.33388154652051 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.33292469269496 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.33065047107664 bayes_pls_golite062009
metal ion transmembrane transporter activity 1.31602086166435 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 0.28050944646617 bayes_pls_golite062009
active transmembrane transporter activity 0.194344891491143 bayes_pls_golite062009
phosphatase activity 0.159899259988948 bayes_pls_golite062009
cation-transporting ATPase activity 0.15490458026932 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.103902756538853 bayes_pls_golite062009
primary active transmembrane transporter activity 0.053543166906854 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.041293091790546 bayes_pls_golite062009
binding 0.0209333912048011 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle