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View Structure Prediction Details

Protein: RNA14
Organism: Saccharomyces cerevisiae
Length: 677 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNA14.

Description E-value Query
Range
Subject
Range
RNA14 - Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of m...
RNA14_YEAST - mRNA 3'-end-processing protein RNA14 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RNA...
gi|190408292 - gi|190408292|gb|EDV11557.1| mRNA 3'-end processing protein RNA14 [Saccharomyces cerevisiae RM11-1a]
gi|151946219 - gi|151946219|gb|EDN64450.1| cleavage and polyadenylation factor CF I component involved in pre-mRNA ...
0.0 [1..677] [1..677]
gi|28201783, gi|... - sp|Q9BZJ0|CRN1_HUMAN Crooked neck-like protein 1 (Crooked neck homolog) (hCrn) (CGI-201) (MSTP021), ...
4.0E-65 [7..586] [204..741]
CRNL1_MOUSE - Crooked neck-like protein 1 OS=Mus musculus GN=Crnkl1 PE=1 SV=1
CRNL1_RAT - Crooked neck-like protein 1 OS=Rattus norvegicus GN=Crnkl1 PE=2 SV=1
3.0E-56 [7..586] [43..580]
RNA14_SCHPO - mRNA 3'-end-processing protein rna14 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rna14...
rna14 - mRNA cleavage and polyadenylation specificity factor complex subunit Rna14
8.0E-55 [2..567] [29..592]
gi|9757719, gi|1... - gi|9757719|dbj|BAB08244.1| CRN (crooked neck) protein [Arabidopsis thaliana], gi|15237354|ref|NP_199...
3.0E-54 [2..594] [35..580]

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Predicted Domain #1
Region A:
Residues: [1-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSTTPDLL YPSADKVAEP SDNIHGDELR LRERIKDNPT NILSYFQLIQ YLETQESYAK  60
   61 VREVYEQFHN TFPFYSPAWT LQLKGELARD EFETVEKILA QCLSGKLENN DLSLWSTYLD 120
  121 YIRRKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.69897
Match: 1hz4A_
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.12690485191789 bayes_pls_golite062009
transcription regulator activity 1.26149030245805 bayes_pls_golite062009
RNA binding 1.1868411700113 bayes_pls_golite062009
DNA binding 0.9531600253493 bayes_pls_golite062009
protein binding 0.931467806305272 bayes_pls_golite062009
nucleic acid binding 0.93037889019021 bayes_pls_golite062009
transcription factor activity 0.374364600772076 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [127-226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLITGGQEAR AVIVKAFQLV MQKCAIFEPK SSSFWNEYLN FLEQWKPFNK WEEQQRIDML  60
   61 REFYKKMLCV PFDNLEKMWN RYTQWEQEIN SLTARKFIGE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.69897
Match: 1hz4A_
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [227-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSAEYMKARS LYQEWLNVTN GLKRASPINL RTANKKNIPQ PGTSDSNIQQ LQIWLNWIKW  60
   61 ERENKLMLSE DMLSQRISYV YKQGIQYMIF SAEMWYDYSM YISENSDRQN ILYTALLANP 120
  121 DSPSLTFKLS ECYELDN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.39794
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [364-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSESVSNCFD KCTQTLLSQY KKIASDVNSG EDNNTEYEQE LLYKQREKLT FVFCVYMNTM  60
   61 KRISGLSAAR TVFGKCRKLK RILTHDVYVE NAYLEFQNQN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.39794
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [464-591]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYKTAFKVLE LGLKYFQNDG VYINKYLDFL IFLNKDSQIK TLFETSVEKV QDLTQLKEIY  60
   61 KKMISYESKF GNLNNVYSLE KRFFERFPQE NLIEVFTSRY QIQNSNLIKK LELTYMYNEE 120
  121 EDSYFSSG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.39794
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [592-677]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGDGHHGSYN MSSSDRKRLM EETGNNGNFS NKKFKRDSEL PTEVLDLLSV IPKRQYFNTN  60
   61 LLDAQKLVNF LNDQVEIPTV ESTKSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle