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View Structure Prediction Details

Protein: CAC2
Organism: Saccharomyces cerevisiae
Length: 468 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAC2.

Description E-value Query
Range
Subject
Range
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
0.0 [5..463] [833..1268]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [3..467] [938..1380]

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Predicted Domain #1
Region A:
Residues: [1-48]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEASHLQIYW HDSQPVYSLT FQKNSANDKL FTAGGDNKVR IWKLNRDE

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 5.0
Match: PF00400
Description: WD domain, G-beta repeat

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 2.79445416141967 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
nucleic acid binding 2.30918780727915 bayes_pls_golite062009
transcription repressor activity 2.29049708962212 bayes_pls_golite062009
dynein binding 1.74989209255308 bayes_pls_golite062009
DNA binding 1.71685536470455 bayes_pls_golite062009
transcription corepressor activity 1.41752877005447 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
cytoskeletal protein binding 1.19593750149343 bayes_pls_golite062009
transcription factor activity 1.08768505897883 bayes_pls_golite062009
0.88172763425403 bayes_pls_golite062009
histone binding 0.685319917508843 bayes_pls_golite062009
DNA-dependent ATPase activity 0.625780732991652 bayes_pls_golite062009
actin binding 0.529861581509437 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
snoRNA binding 0.347797037104681 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
DNA helicase activity 0.220747580531792 bayes_pls_golite062009
structural molecule activity 0.0936365746095786 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [49-468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGQNGGVRKI ESLDFLGSLT HHEQAINVIR FNSKGDVLAS AGDDGQVLLW KQEDPNTQQE  60
   61 SVVRPFGMDA ETSEADENKE KWVVWKRLRG GSGATAAAEI YDLAWSPDNR NIVVACMDNS 120
  121 IRLFDVGAGM LVCGQSDHGH YVQGVAWDPL NQFILSQSAD RSLHVYGVIL SSAGVVTGLK 180
  181 LRSKIAKAEL PCPGDVLRTN YLFHNETLPS FFRRCSISPC GGLVVIPSGV YKVAGDEVAN 240
  241 CVYVYTRSGI LNSAGGVKNR PAIRIPSLKK PALMAAFSPV FYETCQKSVL KLPYKLVFAI 300
  301 ATTNEVLVYD TDVLEPLCVV GNIHYSPITD LAWSEDGSTL LISSTDGFCS YVSIDTETQF 360
  361 GSRIEPPAMH AEPLDTDESA VAAKNQREAG GIVNMLPVKK IPCNSSDSKK RRIHPTPVDL 420
  421 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.491979
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle