| Protein: | YRF1-4 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1382 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YRF1-4.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [159..1382] | [1..1224] |
|
|
0.0 | [15..1382] | [315..1681] |
|
Region A: Residues: [1-93] |
1 11 21 31 41 51
| | | | | |
1 MWKTLGRVEQ LLPYASLILR NREVLFREPK RGIDEYLEND SFFQMIPVKY REIVLPKLRR 60
61 DTNKMTAALK NKVAVAIDEL TVPLMWMIHF AVG
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.591 | 0.117 | DNA helicase activity | a.39.1 | EF-hand |
| View | Download | 0.684 | 0.001 | DNA helicase activity | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.639 | 0.001 | DNA helicase activity | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.563 | 0.001 | DNA helicase activity | a.60.13 | Putative methyltransferase TM0872, insert domain |
| View | Download | 0.753 | N/A | N/A | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.528 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.526 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.486 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.466 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.457 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.430 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.428 | N/A | N/A | a.91.1 | Regulator of G-protein signalling, RGS |
| View | Download | 0.425 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.405 | N/A | N/A | a.49.1 | C-terminal domain of B transposition protein |
| View | Download | 0.402 | N/A | N/A | a.28.2 | Colicin E immunity proteins |
| View | Download | 0.396 | N/A | N/A | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.394 | N/A | N/A | a.24.15 | FAD-dependent thiol oxidase |
| View | Download | 0.389 | N/A | N/A | a.28.1 | ACP-like |
| View | Download | 0.360 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.352 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.347 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.342 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.340 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.335 | N/A | N/A | a.3.1 | Cytochrome c |
| View | Download | 0.330 | N/A | N/A | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.324 | N/A | N/A | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.323 | N/A | N/A | a.2.3 | Chaperone J-domain |
| View | Download | 0.320 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.319 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.315 | N/A | N/A | a.101.1 | Uteroglobin-like |
| View | Download | 0.304 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.296 | N/A | N/A | b.34.1 | C-terminal domain of transcriptional repressors |
| View | Download | 0.293 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.293 | N/A | N/A | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.292 | N/A | N/A | a.39.4 | Hypothetical protein MTH865 |
| View | Download | 0.288 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.283 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.282 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.277 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.277 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.267 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.266 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.257 | N/A | N/A | a.65.1 | Annexin |
| View | Download | 0.251 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.250 | N/A | N/A | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.243 | N/A | N/A | a.60.1 | SAM/Pointed domain |
| View | Download | 0.236 | N/A | N/A | d.6.1 | Prion-like |
| View | Download | 0.236 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.230 | N/A | N/A | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.229 | N/A | N/A | d.26.1 | FKBP-like |
| View | Download | 0.226 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.223 | N/A | N/A | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.220 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.219 | N/A | N/A | a.79.1 | Antitermination factor NusB |
| View | Download | 0.216 | N/A | N/A | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.212 | N/A | N/A | d.55.1 | Ribosomal protein L22 |
| View | Download | 0.207 | N/A | N/A | a.17.1 | p8-MTCP1 |
| View | Download | 0.203 | N/A | N/A | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.202 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.202 | N/A | N/A | a.96.1 | DNA-glycosylase |
|
Region A: Residues: [94-173] |
1 11 21 31 41 51
| | | | | |
1 YPYRYPELQL LAFAGPQRNV YVDDTTRRIQ LYTDYNKNGS SEPRLKTLDG LTSDYVFYFV 60
61 TVLRQMQICA LGNSYDAFNH
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.502 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.459 | d.95.2 | Homing endonucleases |
| View | Download | 0.586 | d.34.1 | DNA-binding domain of Mlu1-box binding protein MBP1 |
| View | Download | 0.548 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.487 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.456 | a.77.1 | DEATH domain |
| View | Download | 0.453 | d.222.1 | YbaB-like |
| View | Download | 0.437 | d.58.17 | Metal-binding domain |
| View | Download | 0.417 | a.21.1 | HMG-box |
| View | Download | 0.417 | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.416 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.414 | a.150.1 | Anti-sigma factor AsiA |
| View | Download | 0.411 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.400 | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.395 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.393 | b.114.1 | N-utilization substance G protein NusG, insert domain |
| View | Download | 0.391 | a.126.1 | Serum albumin-like |
| View | Download | 0.382 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.381 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.373 | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.356 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.335 | a.77.1 | DEATH domain |
| View | Download | 0.312 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.306 | d.93.1 | SH2 domain |
| View | Download | 0.304 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.299 | a.77.1 | DEATH domain |
| View | Download | 0.291 | b.84.2 | Rudiment single hybrid motif |
| View | Download | 0.290 | d.93.1 | SH2 domain |
| View | Download | 0.288 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.277 | a.118.14 | FliG |
| View | Download | 0.277 | b.40.2 | Bacterial enterotoxins |
| View | Download | 0.275 | d.13.1 | HIT-like |
| View | Download | 0.273 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.273 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.269 | d.15.7 | Immunoglobulin-binding domains |
| View | Download | 0.263 | d.93.1 | SH2 domain |
| View | Download | 0.263 | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.257 | d.13.1 | HIT-like |
| View | Download | 0.256 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.249 | d.233.1 | Inhibitor of vertebrate lysozyme, Ivy |
| View | Download | 0.249 | a.46.1 | Methionine synthase domain |
| View | Download | 0.248 | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.247 | a.74.1 | Cyclin-like |
| View | Download | 0.230 | d.9.2 | Description not found. |
| View | Download | 0.227 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.226 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.226 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.222 | c.55.4 | Translational machinery components |
| View | Download | 0.220 | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.211 | a.118.8 | TPR-like |
| View | Download | 0.201 | d.16.1 | FAD-linked reductases, C-terminal domain |
| Term | Confidence | Notes |
| binding | 0.36550713198424 | bayes_pls_golite062009 |
| catalytic activity | 0.234613562021476 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.166100211611062 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.159702441149605 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.149170905385965 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.147838751017739 | bayes_pls_golite062009 |
| hydrolase activity | 0.0436758932827116 | bayes_pls_golite062009 |
|
Region A: Residues: [174-314] |
1 11 21 31 41 51
| | | | | |
1 DPWMDVVGFE DPDQVTNRDI SRIVLYSYMF LNTAKGCLVE YATFRQYMRE LPKNAPQKLN 60
61 FREMRQGLIA LGRHCVGSRF ETDLYESATS ELMANHSVQT GRNIYGVDSF SLTSVSGTTA 120
121 TLLQERASER WIQWLGLESD Y
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.406 | 0.057 | DNA helicase activity | a.26.1 | 4-helical cytokines |
| View | Download | 0.427 | 0.035 | DNA helicase activity | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.699 | 0.023 | DNA helicase activity | a.74.1 | Cyclin-like |
| View | Download | 0.442 | 0.006 | DNA helicase activity | d.136.1 | Phospholipase D/nuclease |
| View | Download | 0.402 | N/A | N/A | a.126.1 | Serum albumin-like |
| View | Download | 0.348 | N/A | N/A | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.263 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.263 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.261 | N/A | N/A | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.251 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.248 | N/A | N/A | a.91.1 | Regulator of G-protein signalling, RGS |
| View | Download | 0.225 | N/A | N/A | a.40.1 | Calponin-homology domain, CH-domain |
| View | Download | 0.225 | N/A | N/A | a.69.1 | C-terminal domain of alpha and beta subunits of F1 ATP synthase |
| View | Download | 0.224 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.212 | N/A | N/A | a.74.1 | Cyclin-like |
|
Region A: Residues: [315-778] |
1 11 21 31 41 51
| | | | | |
1 HCSFSSTRNA EDVVAGEAAS SDHHQKISRV TRKRPREPKS TNDILVAGRK LFGSSFEFRD 60
61 LHQLRLCHEI YMADTPSVAV QAPPGYGKTE LFHLPLIALA SKGDVKYVSF LFVPYTVLLA 120
121 NCMIRLSRCG CLNVAPVRNF IEEGCDGVTD LYVGIYDDLA STNFTDRIAA WENIVECTFR 180
181 TNNVKLGYLI VDEFHNFETE VYRQSQFGGI TNLDFDAFEK AIFLSGTAPE AVADAALQRI 240
241 GLTGLAKKSM DINELKRSED LSRGLSSYPT RMFNLIKEKS EVPLGHVHKI WKKVESQPEE 300
301 ALKLLLALFE IEPESKAIVV ASTTNEVEEL ACSWRKYFRV VWIHGKLGAA EKVSRTKEFV 360
361 TDGSMRVLIG TKLVTEGIDI KQLMMVIMLD NRLNIIELIQ GVGRLRDGGL CYLLSRKNSW 420
421 AARNRKGELP PIKEGCITEQ VREFYGLESK KGKKGQHVGC CGSR
|
| Detection Method: | |
| Confidence: | 168.0 |
| Match: | 1fuuA_ |
| Description: | Initiation factor 4a |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [779-1007] |
1 11 21 31 41 51
| | | | | |
1 TDLSADTVEL IERMDRLAEK QATASMSIIA LPSSFQESNS SDRCRKYCSS DEDSDTCIHG 60
61 SANASTNATT NSSTNATTTA STNVRTSATT TASINVRTSA ITTESTNSST NATTTASTNV 120
121 RTSATTTASI NVRTSATTTE STNSNTSATT TESTDSNTSA TTTESTDSNT SATTTASTNS 180
181 STNATTTAST NSSTNATTTE STNASAKEDA NKDGNAEDNR FHPVTDINK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1008-1382] |
1 11 21 31 41 51
| | | | | |
1 ESYKRKGSQM VLLERKKLKA QFPNTSENMN VLQFLGFRSD EIKHLFLYGI DVYFCPEGVF 60
61 TQYGLCKGCQ KMFELCVCWA GQKVSYRRMA WEALAVERML RNDEEYKEYL EDIEPYHGDP 120
121 VGYLKYFSVK RGEIYSQIQR NYAWYLAITR RRETISVLDS TRGKQGSQVF RMSGRQIKEL 180
181 YYKVWSNLRE SKTEVLQYFL NWDEKKCREE WEAKDDTVFV EALEKVGVFQ RLRSMTSAGL 240
241 QGPQYVKLQF SRHHRQLRSR YELSLGMHLR DQLALGVTPS KVPHWTAFLS MLIGLFYNKT 300
301 FRQKLEYLLE QISEVWLLPH WLDLANVEVL AADNTRVPLY MLMVAVHKEL DSDDVPDGRF 360
361 DIILLCRDSS REVGE
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
