| Protein: | SST2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 698 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SST2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..698] | [1..698] |
|
|
0.0 | [11..562] | [11..505] |
|
|
5.0E-67 | [335..625] | [637..913] |
|
|
1.0E-61 | [377..632] | [111..361] |
|
|
2.0E-61 | [377..632] | [174..424] |
|
Region A: Residues: [1-217] |
1 11 21 31 41 51
| | | | | |
1 MVDKNRTLHE LSSKNFSRTP NGLIFTNDLK TVYSIFLICL DLKEKKHSSD TKSFLLTAFT 60
61 KHFHFTFTYQ EAIKAMGQLE LKVDMNTTCI NVSYNIKPSL ARHLLTLFMS SKLLHTPQDR 120
121 TRGEPKEKVL FQPTPKGVAV LQKYVRDIGL KTMPDILLSS FNSMKLFTFE RSSVTDSIIH 180
181 SDYLIHILFI KMMGAKPNVW SPTNADDPLP CLSSLLE
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [218-277] |
1 11 21 31 41 51
| | | | | |
1 YTNNDDTFTF EKSKPEQGWQ AQIGNIDIND LERVSPLAHR FFTNPDSESH TQYYVSNAGI 60
61
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.369 | 0.800 | GTPase activator activity | d.211.1 | Ankyrin repeat |
| View | Download | 0.278 | 0.800 | GTPase activator activity | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.201 | 0.800 | GTPase activator activity | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| Term | Confidence | Notes |
| DNA binding | 3.26215136954128 | bayes_pls_golite062009 |
| nucleic acid binding | 3.20757869683617 | bayes_pls_golite062009 |
| binding | 2.73671056234733 | bayes_pls_golite062009 |
| transcription factor activity | 2.55529689278984 | bayes_pls_golite062009 |
| transcription regulator activity | 2.05637852290839 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.01485346767161 | bayes_pls_golite062009 |
| signal transducer activity | 0.992792292243706 | bayes_pls_golite062009 |
| molecular transducer activity | 0.992792292243706 | bayes_pls_golite062009 |
| transcription activator activity | 0.897659561486815 | bayes_pls_golite062009 |
| transcription repressor activity | 0.803693565413327 | bayes_pls_golite062009 |
| protein binding | 0.726445167461826 | bayes_pls_golite062009 |
| receptor binding | 0.108282618387842 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.0824467927265171 | bayes_pls_golite062009 |
|
Region A: Residues: [278-356] |
1 11 21 31 41 51
| | | | | |
1 RLFENKTFGT SKKIVIKYTF TTKAIWQWIM DCTDIMHVKE AVSLAALFLK TGLIVPVLLQ 60
61 PSRTDKKKFQ ISRSSFFTL
|
| Detection Method: | |
| Confidence: | 15.920819 |
| Match: | PF00610 |
| Description: | Domain found in Dishevelled, Egl-10, and Pleckstrin |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| GTPase regulator activity | 1.83884232402739 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.81253255528145 | bayes_pls_golite062009 |
| GTPase activator activity | 1.79347668842628 | bayes_pls_golite062009 |
| binding | 1.71250041369331 | bayes_pls_golite062009 |
| enzyme activator activity | 1.54570017870363 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.39953365194488 | bayes_pls_golite062009 |
| protein binding | 1.34804002381061 | bayes_pls_golite062009 |
| signal transducer activity | 1.14361809679544 | bayes_pls_golite062009 |
| molecular transducer activity | 1.14361809679544 | bayes_pls_golite062009 |
| beta-catenin binding | 0.41692824983039 | bayes_pls_golite062009 |
| I-SMAD binding | 0.255267853221551 | bayes_pls_golite062009 |
|
Region A: Residues: [357-610] |
1 11 21 31 41 51
| | | | | |
1 SKRGWDLVSW TGCKSNNIRA PNGSTIDLDF TLRGHMTVRD EKKTLDDSEG FSQDMLISSS 60
61 NLNKLDYVLT DPGMRYLFRR HLEKELCVEN LDVFIEIKRF LKKMTILKKL IDSKHCDKKS 120
121 NTSTSKNNIV KTIDSALMKQ ANECLEMAYH IYSSYIMIGS PYQLNIHHNL RQNISDIMLH 180
181 PHSPLSEHFP TNLYDPSPAS AESAASSISS TEADTLGEPP EVSLKPSKNL SNENCSFKKQ 240
241 GFKHQLKEYK PAPL
|
| Detection Method: | |
| Confidence: | 48.69897 |
| Match: | 1agrE_ |
| Description: | Regulator of G-protein signalling 4, RGS4 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [611-698] |
1 11 21 31 41 51
| | | | | |
1 TLAETHSPNA SVENSHTIVR YGMDNTQNDT KSVESFPATL KVLRKLYPLF EIVSNEMYRL 60
61 MNNDSFQKFT QSDVYKDASA LIEIQEKC
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.609 | a.7.8 | GAT domain |
| View | Download | 0.572 | a.24.2 | Aspartate receptor, ligand-binding domain |
| View | Download | 0.558 | a.22.1 | Histone-fold |
| View | Download | 0.557 | a.24.3 | Cytochromes |
| View | Download | 0.567 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.503 | a.29.2 | Bromodomain |
| View | Download | 0.483 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.474 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.432 | d.188.1 | Prokaryotic ribosomal protein L17 |
| View | Download | 0.387 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.381 | a.22.1 | Histone-fold |
| View | Download | 0.344 | a.2.3 | Chaperone J-domain |
| View | Download | 0.342 | a.46.1 | Methionine synthase domain |
| View | Download | 0.322 | a.47.2 | t-snare proteins |
| View | Download | 0.320 | a.2.7 | tRNA-binding arm |
| View | Download | 0.318 | a.19.1 | Fertilization protein |
| View | Download | 0.286 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.277 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.276 | a.7.7 | BAG domain |
| View | Download | 0.273 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.268 | d.58.1 | 4Fe-4S ferredoxins |
| View | Download | 0.252 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.243 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.240 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.234 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.229 | g.52.1 | Inhibitor of apoptosis (IAP) repeat |
| View | Download | 0.227 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.226 | a.118.8 | TPR-like |
| View | Download | 0.223 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.220 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.214 | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.212 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.211 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.209 | a.26.1 | 4-helical cytokines |
| View | Download | 0.201 | a.26.1 | 4-helical cytokines |
| View | Download | 0.201 | a.130.1 | Chorismate mutase II |
