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Protein Overview: AXIN1_RAT

General Information:
Name(s) found: AXIN1_RAT [Swiss-Prot]
Description(s) found:
Found 5 descriptions.
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  • Axin-1 OS=Rattus norvegicus GN=Axin1 PE=1 SV=3 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 827 amino acids

    Gene Ontology:
    Cellular Component: beta-catenin destruction complex [UNKNOWN]
    nucleus [UNKNOWN]
    lateral plasma membrane [UNKNOWN]
    cytoplasm [UNKNOWN][IEA]
    cytosol [UNKNOWN]
    cytoplasmic vesicle [IDA]
    cytoplasmic membrane-bounded vesicle [UNKNOWN]
    synapse [IDA]
    intracellular [IEA]
    Biological Process: sensory perception of sound [UNKNOWN]
    multicellular organismal development [IEA]
    protein catabolic process [UNKNOWN]
    positive regulation of JNK cascade [ISS]
    positive regulation of protein ubiquitination [UNKNOWN]
    Wnt receptor signaling pathway [UNKNOWN][IPI]
    Wnt receptor signaling pathway through beta-catenin [TAS]
    positive regulation of peptidyl-threonine phosphorylation [UNKNOWN]
    negative regulation of Wnt receptor signaling pathway [UNKNOWN][TAS]
    positive regulation of peptidyl-serine phosphorylation [UNKNOWN]
    Molecular Function: identical protein binding [IPI]
    protein binding [UNKNOWN][IPI]
    protein homodimerization activity [ISS]
    SMAD binding [UNKNOWN]
    armadillo repeat domain binding [IDA]
    beta-catenin binding [UNKNOWN][IDA][IPI]
    I-SMAD binding [UNKNOWN]
    signal transducer activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVQEQGFPL DLGASFTEDA PRPPVPGEEG ELVSTDSRPV NHSFCSGKGT SIKSETSTAT  60
   61 PRRSDLDLGY EPEGSASPTP PYLRWAESLH SLLDDQDGIS LFRTFLKQEG CADLLDFWFA 120
  121 CSGFRKLEPC DSNEEKRLKL ARAIYRKYIL DSNGIVSRQT KPATKSFIKD CVMKQQIDPA 180
  181 MFDQAQTEIQ STMEENTYPS FLKSDIYLEY TRTGSESPKV CSDQSSGSGT GKGMSGYLPT 240
  241 LNEDEEWKCD QDADEDDGRD SVPPSRLTQK LLLETAAPRA PSSRRYNEGR ELRYGSWREP 300
  301 VNPYYVNSGY ALAPATSAND SEQQSLSSDA DTLSLTDSSV DGIPPYRIRK QHRREMQESV 360
  361 QVNGRVPLPH IPRTYRMPKE IRVEPQKFAE ELIHRLEAVQ RTREAEEKLE ERLKRVRMEE 420
  421 EGEDGEMPSG PMASHKLPSV PAWHHFPPRY VDMGCSGLRD AHEENPESIL DEHVQRVMRT 480
  481 PGCQSPGPGH RSPDSGHVAK TAVLGGTASG HGKHAPKLGL KLDSAGLHHH RHVHHHVHHN 540
  541 SARPKEQMEA EAARRVQSSF SWGPETHGHA KPRSYSESTG TNPSAGDLAF GGKASAPSKR 600
  601 NTKKAESGKN ASAEVPSTTE DAEKNQKIMQ WIIEGEKEIS RHRKAGHGSS GMRKQQAHES 660
  661 SRPLSIERPG AVHPWVSAQL RNSVQPSHLF IQDPTMPPNP APNPLTQLEE ARRRLEEEEK 720
  721 RANKLPSKQR TKSQRKAGGG SAPPCDSIVV AYYFCGEPIP YRTLVRGRAV TLGQFKELLT 780
  781 KKGSYRYYFK KVSDEFDCGV VFEEVREDEA ILPVFEEKII GKVEKVD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle