| Protein: | VAC14 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 880 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VAC14.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..880] | [1..880] |
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0.0 | [1..799] | [1..740] |
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|
0.0 | [1..797] | [9..665] |
|
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0.0 | [393..801] | [1..503] |
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0.0 | [144..800] | [25..666] |
|
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0.0 | [1..449] | [8..406] |
|
Region A: Residues: [1-199] |
1 11 21 31 41 51
| | | | | |
1 MEKSIAKGLS DKLYEKRKAA ALELEKLVKQ CVLEGDYDRI DKIIDELCRD YAYALHQPMA 60
61 RNAGLMGLAA TAIALGINDV GRYLRNILPP VLACFGDQND QVRFYACESL YNIAKIAKGE 120
121 ILVYFNEIFD VLCKISADTE NSVRGAAELL DRLIKDIVAE RASNYISIVN NGSHGLLPAI 180
181 KTDPISGDVY QEEYEQDNQ
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.835 | 0.070 | vacuole inheritance | a.118.1 | ARM repeat |
| View | Download | 0.571 | 0.070 | vacuole inheritance | a.87.1 | DBL homology domain (DH-domain) |
| View | Download | 0.881 | 0.070 | vacuole inheritance | a.118.8 | TPR-like |
| View | Download | 0.559 | 0.070 | vacuole inheritance | f.35.1 | Multidrug efflux transporter AcrB transmembrane domain |
| View | Download | 0.551 | 0.070 | vacuole inheritance | a.118.1 | ARM repeat |
| View | Download | 0.527 | 0.070 | vacuole inheritance | a.118.1 | ARM repeat |
| View | Download | 0.504 | 0.070 | vacuole inheritance | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.491 | 0.070 | vacuole inheritance | a.118.9 | ENTH/VHS domain |
| View | Download | 0.466 | 0.070 | vacuole inheritance | a.146.1 | Telomeric repeat binding factor (TRF) dimerisation domain |
| View | Download | 0.465 | 0.070 | vacuole inheritance | a.172.1 | Helical scaffold and wing domains of SecA |
| View | Download | 0.465 | 0.070 | vacuole inheritance | a.25.1 | Ferritin-like |
| View | Download | 0.446 | 0.070 | vacuole inheritance | a.95.1 | Influenza virus matrix protein M1 |
| View | Download | 0.444 | 0.070 | vacuole inheritance | a.24.1 | Apolipoprotein |
| View | Download | 0.418 | 0.070 | vacuole inheritance | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.400 | 0.070 | vacuole inheritance | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.395 | 0.070 | vacuole inheritance | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.383 | 0.070 | vacuole inheritance | a.118.8 | TPR-like |
| View | Download | 0.372 | 0.070 | vacuole inheritance | a.118.9 | ENTH/VHS domain |
| View | Download | 0.371 | 0.070 | vacuole inheritance | a.118.1 | ARM repeat |
| View | Download | 0.367 | 0.070 | vacuole inheritance | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.364 | 0.070 | vacuole inheritance | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.364 | 0.070 | vacuole inheritance | a.118.9 | ENTH/VHS domain |
| View | Download | 0.361 | 0.070 | vacuole inheritance | d.210.1 | Argininosuccinate synthetase, C-terminal domain |
| View | Download | 0.361 | 0.070 | vacuole inheritance | a.118.8 | TPR-like |
| View | Download | 0.358 | 0.070 | vacuole inheritance | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.357 | 0.070 | vacuole inheritance | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.349 | 0.070 | vacuole inheritance | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.344 | 0.070 | vacuole inheritance | a.118.9 | ENTH/VHS domain |
| View | Download | 0.337 | 0.070 | vacuole inheritance | a.1.1 | Globin-like |
| View | Download | 0.323 | 0.070 | vacuole inheritance | a.118.10 | Phosphoinositide-binding clathrin adaptor, N-terminal domain |
| View | Download | 0.305 | 0.070 | vacuole inheritance | a.146.1 | Telomeric repeat binding factor (TRF) dimerisation domain |
| View | Download | 0.304 | 0.070 | vacuole inheritance | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.302 | 0.070 | vacuole inheritance | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.289 | 0.070 | vacuole inheritance | a.87.1 | DBL homology domain (DH-domain) |
| View | Download | 0.289 | 0.070 | vacuole inheritance | a.118.8 | TPR-like |
| View | Download | 0.287 | 0.070 | vacuole inheritance | a.118.9 | ENTH/VHS domain |
| View | Download | 0.280 | 0.070 | vacuole inheritance | a.25.1 | Ferritin-like |
| View | Download | 0.269 | 0.070 | vacuole inheritance | d.90.1 | NADH oxidase/flavin reductase |
| View | Download | 0.267 | 0.070 | vacuole inheritance | a.118.1 | ARM repeat |
| View | Download | 0.266 | 0.070 | vacuole inheritance | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.262 | 0.070 | vacuole inheritance | a.118.8 | TPR-like |
| View | Download | 0.259 | 0.070 | vacuole inheritance | a.118.12 | Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain |
| View | Download | 0.257 | 0.070 | vacuole inheritance | e.6.1 | Acyl-CoA dehydrogenase NM domain-like |
| View | Download | 0.254 | 0.070 | vacuole inheritance | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.254 | 0.070 | vacuole inheritance | d.173.1 | Methionine synthase activation domain-like |
| View | Download | 0.251 | 0.070 | vacuole inheritance | c.6.1 | Cellulases |
| View | Download | 0.250 | 0.070 | vacuole inheritance | c.108.1 | HAD-like |
| View | Download | 0.242 | 0.070 | vacuole inheritance | a.146.1 | Telomeric repeat binding factor (TRF) dimerisation domain |
| View | Download | 0.242 | 0.070 | vacuole inheritance | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.242 | 0.070 | vacuole inheritance | f.1.1 | Colicin |
| View | Download | 0.240 | 0.070 | vacuole inheritance | a.118.8 | TPR-like |
| View | Download | 0.240 | 0.070 | vacuole inheritance | a.172.1 | Helical scaffold and wing domains of SecA |
| View | Download | 0.239 | 0.070 | vacuole inheritance | d.67.3 | Ribosome recycling factor, RRF |
| View | Download | 0.237 | 0.070 | vacuole inheritance | a.138.1 | Multiheme cytochromes |
| View | Download | 0.235 | 0.070 | vacuole inheritance | d.173.1 | Methionine synthase activation domain-like |
| View | Download | 0.232 | 0.070 | vacuole inheritance | d.67.3 | Ribosome recycling factor, RRF |
| View | Download | 0.230 | 0.070 | vacuole inheritance | a.146.1 | Telomeric repeat binding factor (TRF) dimerisation domain |
| View | Download | 0.225 | 0.070 | vacuole inheritance | a.102.5 | Family 10 polysaccharide lyase |
| View | Download | 0.223 | 0.070 | vacuole inheritance | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.223 | 0.070 | vacuole inheritance | a.63.1 | Apolipophorin-III |
| View | Download | 0.221 | 0.070 | vacuole inheritance | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.220 | 0.070 | vacuole inheritance | a.26.1 | 4-helical cytokines |
| View | Download | 0.217 | 0.070 | vacuole inheritance | d.110.2 | GAF domain-like |
| View | Download | 0.215 | 0.070 | vacuole inheritance | a.24.1 | Apolipoprotein |
| View | Download | 0.211 | 0.070 | vacuole inheritance | c.101.1 | Undecaprenyl diphosphate synthase |
| View | Download | 0.208 | 0.070 | vacuole inheritance | c.80.1 | SIS domain |
| View | Download | 0.207 | 0.070 | vacuole inheritance | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.207 | 0.070 | vacuole inheritance | d.153.1 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) |
| View | Download | 0.207 | 0.070 | vacuole inheritance | a.118.8 | TPR-like |
| View | Download | 0.206 | 0.070 | vacuole inheritance | a.118.9 | ENTH/VHS domain |
| View | Download | 0.206 | 0.070 | vacuole inheritance | a.118.8 | TPR-like |
| View | Download | 0.203 | 0.070 | vacuole inheritance | c.108.1 | HAD-like |
| View | Download | 0.203 | 0.070 | vacuole inheritance | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.200 | 0.070 | vacuole inheritance | f.25.1 | Cytochrome c oxidase subunit III-like |
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Region A: Residues: [200-653] |
1 11 21 31 41 51
| | | | | |
1 LAFSLPKFIP LLTERIYAIN PDTRVFLVDW LKVLLNTPGL ELISYLPSFL GGLFTFLGDS 60
61 HKDVRTVTHT LMDSLLHEVD RISKLQTEIK MKRLERLKML EDKYNNSSTP TKKADGALIA 120
121 EKKKTLMTAL GGLSKPLSME TDDTKLSNTN ETDDERHLTS QEQLLDSEAT SQEPLRDGEE 180
181 YIPGQDINLN FPEVITVLVN NLASSEAEIQ LIALHWIQVI LSISPNVFIP FLSKILSVLL 240
241 KLLSDSDPHI TEIAQLVNGQ LLSLCSSYVG KETDGKIAYG PIVNSLTLQF FDSRIDAKIA 300
301 CLDWLILIYH KAPNQILKHN DSMFLTLLKS LSNRDSVLIE KALSLLQSLC SDSNDNYLRQ 360
361 FLQDLLTLFK RDTKLVKTRA NFIMRQISSR LSPERVYKVI SSILDNYNDT TFVKMMIQIL 420
421 STNLITSPEM SSLRNKLRTC EDGMFFNSLF KSWC
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| Detection Method: | |
| Confidence: | 11.67 |
| Match: | 1b89A |
| Description: | Clathrin heavy chain proximal leg segment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [654-880] |
1 11 21 31 41 51
| | | | | |
1 PNPVSVISLC FVAENYELAY TVLQTYANYE LKLNDLVQLD ILIQLFESPV FTRMRLQLLE 60
61 QQKHPFLHKC LFGILMIIPQ SKAFETLNRR LNSLNIWTSQ SYVMNNYIRQ RENSNFCDSN 120
121 SDISQRSVSQ SKLHFQELIN HFKAVSEEDE YSSDMIRLDH GANNKSLLLG SFLDGIDEDK 180
181 QEIVTPISPM NEAINEEMES PNDNSSVILK DSGSLPFNRN VSDKLKK
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 2.53151481871847 | bayes_pls_golite062009 |
| nucleic acid binding | 1.70854853801477 | bayes_pls_golite062009 |
| protein binding | 1.61131270705552 | bayes_pls_golite062009 |
| transcription regulator activity | 1.1879835276438 | bayes_pls_golite062009 |
| DNA binding | 1.03880684185645 | bayes_pls_golite062009 |
| signal transducer activity | 0.862740830365635 | bayes_pls_golite062009 |
| molecular transducer activity | 0.862740830365635 | bayes_pls_golite062009 |
| structural molecule activity | 0.851103372489505 | bayes_pls_golite062009 |
| translation regulator activity | 0.642878560112121 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.620348955429476 | bayes_pls_golite062009 |
| transcription factor activity | 0.389120912139882 | bayes_pls_golite062009 |
| translation initiation factor activity | 0.286790642914928 | bayes_pls_golite062009 |
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Region A: Residues: [787-880] |
1 11 21 31 41 51
| | | | | |
1 HFQELINHFK AVSEEDEYSS DMIRLDHGAN NKSLLLGSFL DGIDEDKQEI VTPISPMNEA 60
61 INEEMESPND NSSVILKDSG SLPFNRNVSD KLKK
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
