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View Structure Prediction Details

Protein: SGD1
Organism: Saccharomyces cerevisiae
Length: 899 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SGD1.

Description E-value Query
Range
Subject
Range
SGD1_YEAST - Suppressor of glycerol defect protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
SGD1 - Essential nuclear protein, required for biogenesis of the small ribosomal subunit; has a possible ro...
0.0 [1..899] [1..899]
gi|19528255 - gi|19528255|gb|AAL90242.1| GH13383p [Drosophila melanogaster]
0.0 [9..810] [98..858]
gi|10047283 - gi|10047283|dbj|BAB13430.1| KIAA1604 protein [Homo sapiens]
0.0 [201..809] [44..630]
gi|6503305, gi|2... - gi|6503305|gb|AAF14681.1|AC011713_29 Contains similarity to gb|U19615 LET 858 gene from Caenorhabdit...
0.0 [2..805] [18..790]
gi|19113048 - gi|19113048|ref|NP_596256.1| hypothetical protein SPBC15D4.16 [Schizosaccharomyces pombe 972h-]
gi|3451474, gi|1... - gi|3451474|emb|CAA20491.1| SPBC13E7.01 [Schizosaccharomyces pombe], ref|NP_596256.1| conserved hypot...
0.0 [240..808] [17..555]
let-858 - status:Confirmed UniProt:Q17336 protein_id:CAB04256.1
0.0 [136..805] [1..626]

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Predicted Domain #1
Region A:
Residues: [1-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKTDGIRIP GVILDELKTL DYSQDERFSI SEGKKRRRGN GKHLSRKEKR KMERADKKRK  60
   61 IISTREINSS RLKSAPTSEK RSANAGVKNV GKQANGKNPI SSDESESNEN WDSDEVLTDE 120
  121 VAEESGEQAM SAEETMKKLE SLKRKAKGIQ GAENSGEIKG NSYEKKHIRN RDTNENFVSY 180
  181 PLAPSDRSAF ERDEMDMQYY AKKLGLKGER KAIHAKDEFD AIGGLLEGLE YFENYGKSDE 240
  241 EYGDFATETN SMRKDDEASE KAFSSDDDLS ASDFEDSDGL SESDNDSVAD SDDNYRREKE 300
  301 NPYVAPTQS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [310-442]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VESYVPPSLR KKLDDSENNS TLSEISKKVN SSLNKLSDSN ITIIITDLNR LYDSLPRQYV  60
   61 TESLTKGILN IISQNQKLLD GFIMNYAALA YTLSKLRGIE VGAFFIQKTV EAFLHHYEEE 120
  121 MENILKDQQS KIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.0
Match: 1hu3A_
Description: Eukaryotic initiation factor eIF4G
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.51289989021257 bayes_pls_golite062009
protein binding 1.48452343997858 bayes_pls_golite062009
nucleic acid binding 0.394131489393838 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [443-595]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKICINIATL LSYCYNFGFV SCRLIYDIIR IFVADPNEFT TELLLRIISI SGQLIRGDDP  60
   61 SALRDIRSEL LKNAKNLKEQ SPRLRFLMDT MSDLKNNRLK PSILATDHHP LKKNLQSILN 120
  121 SSSSWEPLQV SLEDIKNIDS KGKWWLVGAS WRG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.0
Match: 1hu3A_
Description: Eukaryotic initiation factor eIF4G
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [596-837]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMENAFEVSI NNENDASKSK KSKISIEDDL LDDIPDWNII ARQQRMNTDI RRAIFISIMS  60
   61 AQDYLDAFSK LEKLSLKNKQ VLEIPRIVLH CLLADSGSNG YNHYYALVAN KICERYSHLS 120
  121 KSFQFLFWDV IKKFEDKEFD SESDTDEEDD LDDKEKLLRI SNQGRFFGSL LANDILKLDV 180
  181 FKHVPFMGGL NTEGMLFMEI LLFQLFLTVA KKSEKKLKMD ESGNKRIIYS DDYLRDVLTK 240
  241 NV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.40695139302924 bayes_pls_golite062009
protein binding 1.35895139229414 bayes_pls_golite062009
nucleic acid binding 0.342838152542467 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [838-899]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSENMLFILK GLKWFINKKF RYHNFLAGKK GDKAFDRDER RLAWASKAAK SIIDKELENI  60
   61 DS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle