| Protein: | GCD7 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 381 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCD7.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..381] | [1..381] |
|
|
1.0E-97 | [13..376] | [6..351] |
|
|
8.0E-96 | [13..376] | [6..351] |
|
|
2.0E-95 | [11..376] | [2..351] |
|
|
1.0E-93 | [13..376] | [6..351] |
|
|
1.0E-91 | [11..376] | [2..355] |
|
|
2.0E-90 | [14..376] | [6..355] |
|
|
4.0E-90 | [15..376] | [1..407] |
|
Region A: Residues: [1-137] |
1 11 21 31 41 51
| | | | | |
1 MSSQAFTSVH PNAATSDVNV TIDTFVAKLK RRQVQGSYAI ALETLQLLMR FISAARWNHV 60
61 NDLIEQIRDL GNSLEKAHPT AFSCGNVIRR ILAVLRDEVE EDTMSTTVTS TSVAEPLISS 120
121 MFNLLQKPEQ PHQNRKN
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.768 | 0.720 | translation initiation factor activity | a.118.1 | ARM repeat |
| View | Download | 0.804 | 0.036 | mitochondrion | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.940 | 0.010 | mitochondrion | a.118.8 | TPR-like |
| View | Download | 0.713 | 0.003 | translation initiation factor activity | a.74.1 | Cyclin-like |
| View | Download | 0.824 | 0.002 | translation initiation factor activity | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.657 | N/A | N/A | a.46.1 | Methionine synthase domain |
| View | Download | 0.629 | N/A | N/A | a.126.1 | Serum albumin-like |
| View | Download | 0.628 | N/A | N/A | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.621 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.610 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.604 | N/A | N/A | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.585 | N/A | N/A | c.78.2 | Aspartate/glutamate racemase |
| View | Download | 0.584 | N/A | N/A | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.584 | N/A | N/A | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.580 | N/A | N/A | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.569 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.544 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.543 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.520 | N/A | N/A | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.511 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.501 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.488 | N/A | N/A | a.142.1 | PTS-regulatory domain, PRD |
| View | Download | 0.482 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.471 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.470 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.448 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.447 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.442 | N/A | N/A | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.436 | N/A | N/A | a.29.2 | Bromodomain |
| View | Download | 0.432 | N/A | N/A | a.63.1 | Apolipophorin-III |
| View | Download | 0.428 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.421 | N/A | N/A | a.22.1 | Histone-fold |
| View | Download | 0.419 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.418 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.413 | N/A | N/A | d.122.1 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
| View | Download | 0.389 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.381 | N/A | N/A | a.39.2 | Insect pheromon/odorant-binding proteins |
| View | Download | 0.380 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.379 | N/A | N/A | d.58.26 | GHMP Kinase, C-terminal domain |
| View | Download | 0.376 | N/A | N/A | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.374 | N/A | N/A | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.372 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.371 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.369 | N/A | N/A | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.366 | N/A | N/A | d.173.1 | Methionine synthase activation domain-like |
| View | Download | 0.363 | N/A | N/A | a.69.1 | C-terminal domain of alpha and beta subunits of F1 ATP synthase |
| View | Download | 0.353 | N/A | N/A | c.55.3 | Ribonuclease H-like |
| View | Download | 0.351 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.346 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.337 | N/A | N/A | a.11.2 | Second domain of FERM |
| View | Download | 0.335 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.331 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.330 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.330 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.329 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.329 | N/A | N/A | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.325 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.321 | N/A | N/A | c.52.3 | Eukaryotic RPB5 N-terminal domain |
| View | Download | 0.312 | N/A | N/A | a.91.1 | Regulator of G-protein signalling, RGS |
| View | Download | 0.309 | N/A | N/A | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.308 | N/A | N/A | a.2.3 | Chaperone J-domain |
| View | Download | 0.307 | N/A | N/A | d.112.1 | Phoshotransferase/anion transport protein |
| View | Download | 0.304 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.303 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.300 | N/A | N/A | a.118.12 | Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain |
| View | Download | 0.299 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.297 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.297 | N/A | N/A | a.91.1 | Regulator of G-protein signalling, RGS |
| View | Download | 0.296 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.295 | N/A | N/A | a.4.3 | ARID-like |
| View | Download | 0.295 | N/A | N/A | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.292 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.291 | N/A | N/A | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.283 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.277 | N/A | N/A | a.160.1 | Poly(A) polymerase, middle domain |
| View | Download | 0.274 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.270 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.270 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.269 | N/A | N/A | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.263 | N/A | N/A | c.64.1 | Pyruvate-ferredoxin oxidoreductase, PFOR, domain III |
| View | Download | 0.261 | N/A | N/A | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.249 | N/A | N/A | d.65.1 | Hedgehog/DD-pepidase |
| View | Download | 0.248 | N/A | N/A | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.245 | N/A | N/A | a.5.4 | Elongation factor TFIIS domain 2 |
| View | Download | 0.243 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.242 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.235 | N/A | N/A | a.24.3 | Cytochromes |
| View | Download | 0.235 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.233 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.231 | N/A | N/A | a.89.1 | Methyl-coenzyme M reductase alpha and beta chain C-terminal domain |
| View | Download | 0.229 | N/A | N/A | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.229 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.228 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.226 | N/A | N/A | c.1.1 | Triosephosphate isomerase (TIM) |
| View | Download | 0.222 | N/A | N/A | d.163.1 | DNA breaking-rejoining enzymes |
| View | Download | 0.220 | N/A | N/A | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.219 | N/A | N/A | f.32.1 | a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.217 | N/A | N/A | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.216 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.215 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.215 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.214 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.214 | N/A | N/A | d.79.1 | YjgF-like |
| View | Download | 0.213 | N/A | N/A | e.37.1 | Bifunctional dehydrogenase/ferrochelatase Met8p, dimerisation and C-terminal domains |
| View | Download | 0.212 | N/A | N/A | a.19.1 | Fertilization protein |
| View | Download | 0.211 | N/A | N/A | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.211 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.205 | N/A | N/A | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.203 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.203 | N/A | N/A | a.62.1 | Hepatitis B viral capsid (hbcag) |
| View | Download | 0.202 | N/A | N/A | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.202 | N/A | N/A | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| Term | Confidence | Notes |
| translation initiation factor activity | 10.1099993541596 | bayes_pls_golite062009 |
| translation regulator activity | 5.74669335554405 | bayes_pls_golite062009 |
| nucleic acid binding | 2.17718456512191 | bayes_pls_golite062009 |
| transcription regulator activity | 1.9283980201455 | bayes_pls_golite062009 |
| DNA binding | 1.55389679363348 | bayes_pls_golite062009 |
| binding | 1.53908996868286 | bayes_pls_golite062009 |
| catalytic activity | 1.31732715713197 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 1.09424756417577 | bayes_pls_golite062009 |
| transcription factor activity | 0.995059566132783 | bayes_pls_golite062009 |
| CoA-transferase activity | 0.0320953696548698 | bayes_pls_golite062009 |
| protein binding | 0.0293610121675921 | bayes_pls_golite062009 |
|
Region A: Residues: [138-311] |
1 11 21 31 41 51
| | | | | |
1 SSGSSSMKTK TDYRQVAIQG IKDLIDEIKN IDEGIQQIAI DLIHDHEILL TPTPDSKTVL 60
61 KFLITARERS NRTFTVLVTE GFPNNTKNAH EFAKKLAQHN IETLVVPDSA VFALMSRVGK 120
121 VIIGTKAVFV NGGTISSNSG VSSVCECARE FRTPVFAVAG LYKLSPLYPF DVEK
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Region B: Residues: [376-381] |
1 11 21 31 41 51
| | | | | |
1 LDKNKA
|
| Detection Method: | |
| Confidence: | 10.68 |
| Match: | 1m0sA |
| Description: | D-ribose-5-phosphate isomerase (RpiA), catalytic domain; D-ribose-5-phosphate isomerase (RpiA), lid domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [312-375] |
1 11 21 31 41 51
| | | | | |
1 FVEFGGSQRI LPRMDPRKRL DTVNQITDYV PPENIDIYIT NVGGFNPSFI YRIAWDNYKQ 60
61 IDVH
|
| Detection Method: | |
| Confidence: | 10.68 |
| Match: | 1m0sA |
| Description: | D-ribose-5-phosphate isomerase (RpiA), catalytic domain; D-ribose-5-phosphate isomerase (RpiA), lid domain |
| Matching Structure (courtesy of the PDB): |
|
