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View Structure Prediction Details

Protein: GSY2
Organism: Saccharomyces cerevisiae
Length: 705 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GSY2.

Description E-value Query
Range
Subject
Range
gi|151941092 - gi|151941092|gb|EDN59472.1| UDP-glucose-starch glucosyltransferase [Saccharomyces cerevisiae YJM789]
gi|171619 - gi|171619|gb|AAA88716.1| glycogen synthase [Saccharomyces cerevisiae]
0.0 [1..691] [1..691]
GYS1 - glycogen synthase 1 (muscle)
0.0 [4..671] [23..661]
GYS1_RABIT - Glycogen [starch] synthase, muscle OS=Oryctolagus cuniculus GN=GYS1 PE=1 SV=4
0.0 [4..671] [23..661]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [4..671] [23..661]
GYS1_MOUSE - Glycogen [starch] synthase, muscle OS=Mus musculus GN=Gys1 PE=1 SV=2
0.0 [4..671] [23..661]
GYS_NEUCR - Glycogen [starch] synthase OS=Neurospora crassa GN=7F4.080 PE=2 SV=2
GYS_NEUCR - Glycogen [starch] synthase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1...
0.0 [3..686] [9..666]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRDLQNHLL FETATEVANR VGGIYSVLKS KAPITVAQYK DHYHLIGPLN KATYQNEVDI  60
   61 LDWKKPEAFS DEMRPVQHAL QTMESRG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
glycogen phosphorylase activity 4.85572378579745 bayes_pls_golite062009
phosphorylase activity 3.90117606315103 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 3.13569872928774 bayes_pls_golite062009
catalytic activity 2.42803950895063 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.09333759861004 bayes_pls_golite062009
glucosyltransferase activity 1.90464350723601 bayes_pls_golite062009
transferase activity 1.88974698466478 bayes_pls_golite062009
UDP-glycosyltransferase activity 1.65897712372683 bayes_pls_golite062009
UDP-glucosyltransferase activity 1.65637638312265 bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity 0.988654552791302 bayes_pls_golite062009
oxidoreductase activity 0.983614980754643 bayes_pls_golite062009
carbohydrate phosphatase activity 0.459821108931138 bayes_pls_golite062009
binding 0.45826376378159 bayes_pls_golite062009
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity 0.290421196423307 bayes_pls_golite062009
protein binding 0.228850008528478 bayes_pls_golite062009
sugar binding 0.0223079311271377 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [88-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VHFVYGRWLI EGAPKVILFD LDSVRGYSNE WKGDLWSLVG IPSPENDFET NDAILLGYTV  60
   61 AWFLGEVAHL DSQHAIVAHF HEWLAGVALP LCRKRRIDVV TIFTTHATLL GRYLCASGSF 120
  121 DFYNCLESVD VDHEAGRFGI YHRYCIERAA AHSADVFTTV SQITAFEAEH LLKRKPDGIL 180
  181 PNGLNVIKFQ AFHEFQNLHA LKKEKINDFV RGHFHGCFDF DLDNTLYFFI AGRYEYKNKG 240
  241 ADMFIEALAR LNYRLKVSGS KKTVVAFIVM PAK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
glycogen phosphorylase activity 5.43556332287206 bayes_pls_golite062009
phosphorylase activity 4.4363209226962 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 3.70184884300914 bayes_pls_golite062009
catalytic activity 2.65148466065976 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.62403914335522 bayes_pls_golite062009
glucosyltransferase activity 2.48423599937201 bayes_pls_golite062009
UDP-glucosyltransferase activity 2.22592863643386 bayes_pls_golite062009
transferase activity 2.18054407163329 bayes_pls_golite062009
UDP-glycosyltransferase activity 2.13085705769565 bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity 1.55280519670033 bayes_pls_golite062009
oxidoreductase activity 0.974556371594238 bayes_pls_golite062009
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity 0.849686864309466 bayes_pls_golite062009
carbohydrate phosphatase activity 0.78952375993773 bayes_pls_golite062009
binding 0.399722153246393 bayes_pls_golite062009
mannosyltransferase activity 0.253888301381021 bayes_pls_golite062009
protein binding 0.198267161626932 bayes_pls_golite062009
sugar binding 0.14686473522482 bayes_pls_golite062009
drug binding 0.102804615007901 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [361-450]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNSFTVEALK GQAEVRALEN TVHEVTTSIG KRIFDHAIRY PHNGLTTELP TDLGELLKSS  60
   61 DKVMLKRRIL ALRRPEGQLP PIVTHNMVDD 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [451-653]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANDLILNKIR QVQLFNSPSD RVKMIFHPEF LNANNPILGL DYDEFVRGCH LGVFPSYYEP  60
   61 WGYTPAECTV MGVPSITTNV SGFGAYMEDL IETNQAKDYG IYIVDRRFKA PDESVEQLVD 120
  121 YMEEFVKKTR RQRINQRNRT ERLSDLLDWK RMGLEYVKAR QLALRRGYPD QFRELVGEEL 180
  181 NDSNMDALAG GKKLKVARPL SVP

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.04
Match: 1f6dA
Description: UDP-N-acetylglucosamine 2-epimerase
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [654-705]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSPRDLRSNS TVYMTPGDLG TLQEVNNADD YFSLGVNPAA DDDDDGPYAD DS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle