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View Structure Prediction Details

Protein: YLR253W
Organism: Saccharomyces cerevisiae
Length: 569 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR253W.

Description E-value Query
Range		 Subject
Range
gi|151941088 - gi|151941088|gb|EDN59468.1| conserved protein [Saccharomyces cerevisiae YJM789]
MCP2_YEAST - ABC1 family protein MCP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MCP2 PE=1 SV=1
YLR253W - Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi...
 0.0 [1..569] [1..569]
gi|25534796 - pir||AH2425 hypothetical protein all4960 [imported] - Nostoc sp. (strain PCC 7120)
gi|17134098, gi|... - gi|17232452|ref|NP_489000.1| hypothetical protein all4960 [Nostoc sp. PCC 7120], gi|17134098|dbj|BAB...
 0.0 [22..551] [31..526]
YJ19_SYNY3, Y191... - (P73121) Hypothetical protein slr1919, Uncharacterized protein slr1919 OS=Synechocystis sp. (strain ...
gi|7450861 - pir||S75233 ABC transporter slr1919 - Synechocystis sp. (strain PCC 6803)
Y1919_SYNY3 - Uncharacterized protein slr1919 OS=Synechocystis sp. (strain PCC 6803 / Kazusa) GN=slr1919 PE=3 SV=1
 4.0E-97 [56..552] [19..490]
YG62_SCHPO - ABC1 family protein C15C4.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC15C4.02 P...
SPBC15C4.02 - ABC1 kinase family protein
 5.0E-97 [29..550] [71..588]
UBIB_PASMU - Probable ubiquinone biosynthesis protein ubiB OS=Pasteurella multocida GN=ubiB PE=3 SV=1
UBIB_PASMU - Probable protein kinase UbiB OS=Pasteurella multocida (strain Pm70) GN=ubiB PE=3 SV=1
 5.0E-93 [69..563] [9..504]
Y2090_ARATH - Putative ABC1 protein At2g40090 OS=Arabidopsis thaliana GN=At2g40090 PE=2 SV=2
 6.0E-92 [31..557] [8..528]
gi|117616972 - gi|117616972|gb|ABK42504.1| ADCK1 [synthetic construct]
ADCK1_MOUSE - Uncharacterized aarF domain-containing protein kinase 1 OS=Mus musculus GN=Adck1 PE=1 SV=1
 8.0E-92 [39..531] [14..484]

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Predicted Domain #1
Region A:
Residues: [1-153] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMTKAFFNKL PFEVFRRYVR TGKSIPQRSP RTRKSLLVGG TIASAVVLYN FNDTFHDSVK  60
   61 HTALTTKRIA VVTQATTRCF YHYKRALNKS YENKKEREVA LNKCHKMCAL ITLHALRSNG 120
  121 GIYIKLGQHI GAMTYLLPKE WTDTMIPLQD HCP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [154-300] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESTYEEIDEL FKEDLGTSIE DMFLEFNKTP IGVASLAQVH VAKLKNSDGK GSSVAVKCQH  60
   61 PSLKEFIPLD VMLTRTVFEL LDVFFPDYPL TWLGDELQSS IYVELNFTKE AENAEKTRHY 120
  121 FSKFKKQTAL KIPKVIESHK RILIMEY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.522879
Match: 1f3mC_
Description: pak1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein kinase activity 2.78878187773119 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 2.65696220652782 bayes_pls_golite062009
protein serine/threonine kinase activity 2.52043782881479 bayes_pls_golite062009
kinase activity 2.45757516485965 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.08265655536291 bayes_pls_golite062009
binding 1.72646207655432 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
transferase activity 1.09650209608069 bayes_pls_golite062009
ATP binding 0.57612786382221 bayes_pls_golite062009
adenyl ribonucleotide binding 0.533622009869642 bayes_pls_golite062009
protein binding 0.529222066176906 bayes_pls_golite062009
adenyl nucleotide binding 0.516315256680509 bayes_pls_golite062009
purine ribonucleotide binding 0.366733507123411 bayes_pls_golite062009
ribonucleotide binding 0.366674148714169 bayes_pls_golite062009
purine nucleotide binding 0.355425813353478 bayes_pls_golite062009
nucleotide binding 0.350202706382045 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [301-494] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGGKRLDDLE YIDSHGISRS EVSSCLSHIF NNMIFTPNVG IHCDPHGGNL AIRSVKPAKD  60
   61 NGYHNFEIVL FDHGLYRYPS TRTRRLYAKF WLSLLFDKDQ TKMKKYAKGF ANITDEQFPL 120
  121 LAAAITGRSI DAALNYDIST SRTQEEMDVM ANGILEGTLL SDLMSILSRI PRVVLLILKT 180
  181 NDLTRHLDEC LQNP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.522879
Match: 1f3mC_
Description: pak1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [495-569] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGPERTFLIM TQYCAKTVYD EKVERINSEY ARWSIKWMWE NLTNWIVYER RINQLYFYDF  60
   61 VLWWKKFIPK TWLSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle