| Protein: | EST1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 699 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EST1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..699] | [1..699] |
|
|
2.0E-99 | [10..343] | [8..342] |
|
|
0.007 | [121..279] | [88..226] |
|
Region A: Residues: [1-471] |
1 11 21 31 41 51
| | | | | |
1 MDNEEVNEEC MRLFFKNARA HLDKHLTSRL TCDENAYITF RCFLDGIHRK STRFLEELLL 60
61 KQENMYHNNN YERINDSVIP LVLKLLWLQI HEPTLQWFEH WFHDIMRLSN RRKFRVFRIF 120
121 QKKMIQFFKI THRYYYDIIE HLCAKYDMNS VISNALFAKL NLMQYTDGLS THEKIILNTS 180
181 NPLTFSIVIS LQRCVINLGS THFYKTLLNK PSNKPKSVEG FEKSIRYLNI ASLYLPAVGD 240
241 TYFQRAKIYL ITGKFSLYFF ELVRGALVRI PSKCALNNLK DFILTPDFPE RRRLMKKLAI 300
301 LVSKDLKGEK SFFEGQIVLQ FLSIVEHTLV PQSWNASRAS NCWLLKEHLQ MAALKYHSGN 360
361 INVILENLAA TMGSFDLMFT TRKSKEQKNK LKYADLSERQ VFFLDLSFDF IANIIDVVIK 420
421 PSWQKNMEDF RYLAIIRLLM CWIKSYRSIL QYTHRHRKFC TSFALLLNDL I
|
| Detection Method: |  |
| Confidence: | 10.41 |
| Match: | 1b89A |
| Description: | Clathrin heavy chain proximal leg segment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [472-699] |
1 11 21 31 41 51
| | | | | |
1 NSPLNCSGNI YSHRPKRSYL FREDIIFREF SCINFALTDF NDDYVYDSPD MINNIIGCPT 60
61 LTKVLSPKEE CVLRIRSIIF SGMKFLEKND TGVIWNASKY KFDLISPNIK IKRQIALSEI 120
121 SSKINVKTQQ ERVVSSRKVE AKRDEQQRKR AGKIAVTELE KQFANVRRTK KLSPLPEKDG 180
181 VSSELVKHAA SRGRKTITGP LSSDFLSYPD EAIDADEDIT VQVPDTPT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [286-618] |
1 11 21 31 41 51
| | | | | |
1 PDFPERRRLM KKLAILVSKD LKGEKSFFEG QIVLQFLSIV EHTLVPQSWN ASRASNCWLL 60
61 KEHLQMAALK YHSGNINVIL ENLAATMGSF DLMFTTRKSK EQKNKLKYAD LSERQVFFLD 120
121 LSFDFIANII DVVIKPSWQK NMEDFRYLAI IRLLMCWIKS YRSILQYTHR HRKFCTSFAL 180
181 LLNDLINSPL NCSGNIYSHR PKRSYLFRED IIFREFSCIN FALTDFNDDY VYDSPDMINN 240
241 IIGCPTLTKV LSPKEECVLR IRSIIFSGMK FLEKNDTGVI WNASKYKFDL ISPNIKIKRQ 300
301 IALSEISSKI NVKTQQERVV SSRKVEAKRD EQQ
|
| Detection Method: | |
| Confidence: | 2.32 |
| Match: | 1ya0A |
| Description: | Crystal structure of the N-terminal domain of human SMG7 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.45002000313605 | bayes_pls_golite062009 |
| protein binding | 1.41340296563325 | bayes_pls_golite062009 |
| nucleic acid binding | 1.03214696367403 | bayes_pls_golite062009 |
| transcription regulator activity | 1.0247488240855 | bayes_pls_golite062009 |
| DNA binding | 0.812129701902081 | bayes_pls_golite062009 |
| transcription factor activity | 0.142011117504773 | bayes_pls_golite062009 |
| RNA binding | 0.0778145706670981 | bayes_pls_golite062009 |
|
Region A: Residues: [619-699] |
1 11 21 31 41 51
| | | | | |
1 RKRAGKIAVT ELEKQFANVR RTKKLSPLPE KDGVSSELVK HAASRGRKTI TGPLSSDFLS 60
61 YPDEAIDADE DITVQVPDTP T
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
