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View Structure Prediction Details

Protein: PEP3
Organism: Saccharomyces cerevisiae
Length: 918 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEP3.

Description E-value Query
Range
Subject
Range
PEP3_YEAST - Vacuolar membrane protein PEP3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEP3 PE=1...
gi|190406177 - gi|190406177|gb|EDV09444.1| vacuolar membrane protein [Saccharomyces cerevisiae RM11-1a]
gi|207343032 - gi|207343032|gb|EDZ70617.1| YLR148Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|151941310 - gi|151941310|gb|EDN59688.1| carboxypeptidase Y-deficient [Saccharomyces cerevisiae YJM789]
PEP3 - Component of CORVET tethering complex; vacuolar peripheral membrane protein that promotes vesicular ...
0.0 [1..918] [1..918]
gi|12641617 - gi|12641617|emb|CAC27452.1| DigA protein [Emericella nidulans]
gi|40744683, gi|... - gi|67523621|ref|XP_659870.1| hypothetical protein AN2266.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
0.0 [4..916] [24..961]
gi|7959211 - gi|7959211|dbj|BAA95999.1| KIAA1475 protein [Homo sapiens]
0.0 [20..916] [70..985]
gi|15221363 - gi|15221363|ref|NP_172709.1| Pep3/Vps18/deep orange family protein [Arabidopsis thaliana]
0.0 [20..913] [24..971]
dor-PA - The gene deep orange is referred to in FlyBase by the symbol Dmel\dor (CG3093, FBgn0000482). It is a...
0.0 [4..913] [45..997]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [4..913] [45..997]

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Predicted Domain #1
Region A:
Residues: [1-304]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKTRIEEVQ LQFLTGNTEL THLKVSNDQL IVTTQRTIYR INLQDPAIVN HFDCPLSKEL  60
   61 ETIMNVHVSP MGSVILIRTN FGRYMLLKDG EFTQLNKIKN LDLSSLHWIN ETTFLMGIKK 120
  121 TPKLYRVELT GKDITTKLWY ENKKLSGGID GIAYWEGSLL LTIKDNILYW RDVTNMKFPL 180
  181 VLPDESEQFE RLKHHAIKKF DSYNGLFAWV TSNGIVFGDL KEKQMEKDPA SNNFGKFLSS 240
  241 SKVLLNFELP DYQNDKDHLI KDIVLTAFHI LLLRKNTVTM VSQLNNDVVF HETIPRHQLT 300
  301 GSNT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [305-823]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSNEKFLGLV RDSVKETFWC FSNINVFEII IENEPNSVWN LLVRDNKFDK ALSLKGLTVR  60
   61 EIESVKLSKA MYLFHTAKDF HSAAQTLGSM KDLSHFGEIA LNFLQIKDYN DLNVILIKQL 120
  121 DNVPWKSTQV VLSSWIIWNF MKQLNDIELK INTTKPASTD EDNLLNWNLN LKEKSNELTK 180
  181 FLESHLEKLD NETVYQIMSK QNRQNELLIF ASLINDMKFL LSFWIDQGNW YESLKILLTI 240
  241 NNHDLVYKYS LILLLNSPEA TVSTWMKIKD LDPNKLIPTI LKFFTNWQNN SKLITNISEY 300
  301 PENYSLTYLK WCVREVPKMC NPIVYNSILY MMITDPRNDM ILENDIIKFM KSNENKYDLN 360
  361 FQLRLSLKFK KTKTSIFLLT RLNLFEDAID LALKNNLIDD CKVIVNDEIL IEDYKLRKRL 420
  421 WLKIAKHLLL SMKDIDIKQL IRTILNDSNE ILTIKDLLPF FNEYTTIANL KEELIKFLEN 480
  481 HNMKMNEISE DIINSKNLKV EINTEISKFN EIYRILEPG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.30103
Match: 1b89A_
Description: Clathrin heavy chain proximal leg segment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [824-918]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSCDECGKFL QIKKFIVFPC GHCFHWNCII RVILNSNDYN LRQKTENFLK AKSKHNLNDL  60
   61 ENIIVEKCGL CSDININKID QPISIDETEL AKWNE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [816-918]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IYRILEPGKS CDECGKFLQI KKFIVFPCGH CFHWNCIIRV ILNSNDYNLR QKTENFLKAK  60
   61 SKHNLNDLEN IIVEKCGLCS DININKIDQP ISIDETELAK WNE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.57
Match: 2ecnA
Description: No description for 2ecnA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle