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View Structure Prediction Details

Protein: MSL5
Organism: Saccharomyces cerevisiae
Length: 476 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSL5.

Description E-value Query
Range
Subject
Range
SF1-PA - The gene Splicing factor 1 is referred to in FlyBase by the symbol Dmel\SF1 (CG5836, FBgn0025571). I...
372.0 [0..8] [391..257]
gi|54637619, gi|... - gi|54637619|gb|EAL27021.1| GA19167-PA [Drosophila pseudoobscura], gi|125773253|ref|XP_001357885.1| G...
344.0 [0..8] [391..266]
BBP_SCHPO - Branchpoint-bridging protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=bpb1 PE=1 SV=...
bpb1 - zinc finger protein Bpb1
326.0 [0..50] [475..89]
gi|46110397, gi|... - gi|46110397|ref|XP_382256.1| hypothetical protein FG02080.1 [Gibberella zeae PH-1], gi|42546868|gb|E...
326.0 [0..8] [375..1175]
gi|76657842 - gi|76657842|ref|XP_885933.1| PREDICTED: similar to Splicing factor 1 (Zinc finger protein 162) (Tran...
314.0 [0..26] [388..129]
gi|2463198 - gi|2463198|emb|CAA03883.1| splicing factor SF1 [Homo sapiens]
313.0 [0..26] [313..13]
gi|119115501, gi... - gi|119115501|ref|XP_311109.3| ENSANGP00000017356 [Anopheles gambiae str. PEST], gi|116130867|gb|EAA0...
312.0 [0..27] [343..250]
gi|114638375 - gi|114638375|ref|XP_001166276.1| PREDICTED: splicing factor 1 isoform 1 [Pan troglodytes]
310.0 [0..26] [388..140]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFRRINSRY FENRKGSSME EKKAKVPPNV NLSLWRKNTV ESDVHRFNSL PSKISGALTR  60
   61 EQIYSYQVMF RIQEITIKLR TNDFVPPSRK NRSPS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [96-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPVYDAQGK RTNTREQRYR KKLEDERIKL VEIALKTIPY FVPPDDYKRP TKFQDKYYIP  60
   61 VDQYPDVNFV GLLLGPRGRT LRKLQEDSNC KIAIRGRGSV KEGKNASDLP PGAMNFEDPL 120
  121 HCLIIADSED KIQKGIKVCQ NIVIKAVTSP EGQNDLKRGQ LRELAELNGT LREDNRPC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 335.10721
Match: 1k1gA
Description: RNA splicing factor 1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [274-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PICGLKDHKR YDCPNRKIPN IQGIVCKICG QTGHFSRDCN SSSQRMSRFD RNATVNNSAP  60
   61 IQSNDVHYNS NTHPIQAPKR SRYDNNSTEP PLKFPASSRY APSPSPPASH ISRQAQNVTP 120
  121 TPPPGLTSSS FSSGVPGIAP PPLQSPPESE QPKFSLPPPP GMTTVQSSIA PPPGLSGPPG 180
  181 FSNNMGNDIN KPTPPGLQGP PGL

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 14.07
Match:
Description: No description for 1i3qA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle