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View Structure Prediction Details

Protein: MSL5
Organism: Saccharomyces cerevisiae
Length: 476 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSL5.

Description E-value Query
Range
Subject
Range
SF1-PA - The gene Splicing factor 1 is referred to in FlyBase by the symbol Dmel\SF1 (CG5836, FBgn0025571). I...
372.0 [0..8] [391..257]
gi|54637619, gi|... - gi|54637619|gb|EAL27021.1| GA19167-PA [Drosophila pseudoobscura], gi|125773253|ref|XP_001357885.1| G...
344.0 [0..8] [391..266]
BBP_SCHPO - Branchpoint-bridging protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=bpb1 PE=1 SV=...
bpb1 - zinc finger protein Bpb1
326.0 [0..50] [475..89]
gi|46110397, gi|... - gi|46110397|ref|XP_382256.1| hypothetical protein FG02080.1 [Gibberella zeae PH-1], gi|42546868|gb|E...
326.0 [0..8] [375..1175]
gi|76657842 - gi|76657842|ref|XP_885933.1| PREDICTED: similar to Splicing factor 1 (Zinc finger protein 162) (Tran...
314.0 [0..26] [388..129]
gi|2463198 - gi|2463198|emb|CAA03883.1| splicing factor SF1 [Homo sapiens]
313.0 [0..26] [313..13]
gi|119115501, gi... - gi|119115501|ref|XP_311109.3| ENSANGP00000017356 [Anopheles gambiae str. PEST], gi|116130867|gb|EAA0...
312.0 [0..27] [343..250]
gi|114638375 - gi|114638375|ref|XP_001166276.1| PREDICTED: splicing factor 1 isoform 1 [Pan troglodytes]
310.0 [0..26] [388..140]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFRRINSRY FENRKGSSME EKKAKVPPNV NLSLWRKNTV ESDVHRFNSL PSKISGALTR  60
   61 EQIYSYQVMF RIQEITIKLR TNDFVPPSRK NRSPS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.562 N/A N/A d.64.2 Description not found.
View Download 0.412 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.412 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.340 N/A N/A a.159.3 Description not found.
View Download 0.298 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.298 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.242 N/A N/A a.159.3 Description not found.
View Download 0.214 N/A N/A a.144.1 PABC (PABP) domain

Predicted Domain #2
Region A:
Residues: [96-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPVYDAQGK RTNTREQRYR KKLEDERIKL VEIALKTIPY FVPPDDYKRP TKFQDKYYIP  60
   61 VDQYPDVNFV GLLLGPRGRT LRKLQEDSNC KIAIRGRGSV KEGKNASDLP PGAMNFEDPL 120
  121 HCLIIADSED KIQKGIKVCQ NIVIKAVTSP EGQNDLKRGQ LRELAELNGT LREDNRPC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 335.10721
Match: 1k1gA
Description: RNA splicing factor 1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [274-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PICGLKDHKR YDCPNRKIPN IQGIVCKICG QTGHFSRDCN SSSQRMSRFD RNATVNNSAP  60
   61 IQSNDVHYNS NTHPIQAPKR SRYDNNSTEP PLKFPASSRY APSPSPPASH ISRQAQNVTP 120
  121 TPPPGLTSSS FSSGVPGIAP PPLQSPPESE QPKFSLPPPP GMTTVQSSIA PPPGLSGPPG 180
  181 FSNNMGNDIN KPTPPGLQGP PGL

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 14.07
Match:
Description: No description for 1i3qA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle