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View Structure Prediction Details

Protein: PET309
Organism: Saccharomyces cerevisiae
Length: 965 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PET309.

Description E-value Query
Range
Subject
Range
gi|15221621 - gi|15221621|ref|NP_176479.1| pentatricopeptide (PPR) repeat-containing protein [Arabidopsis thaliana...
0.0 [56..956] [53..927]

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Predicted Domain #1
Region A:
Residues: [1-692]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRCAPAVLR NYNYKKGIWS TGVPDHIRKL LRDKSTSPLC SQDERNLVSY FMARGSVPLK  60
   61 SVGSGLTKKA TTSITSNSAT TTFERQYLIK YLYRHQAYGN VIKIAQKFLY TTIGSQRLLK 120
  121 QDASLPELKK FLLSLLILQR GIQLDQAISD IIQRFLLTQK TMVIDLINSI FSRMVIMNMH 180
  181 EEAVYKWVKW MKLVNGHCEF TNYMENKIVL RNFLSFMRQS NVRPDYLSYL KAIQLTQGPA 240
  241 IASQFATTLL FLLTYIRKFS SAEAVWNYKC EHNLPIVSSD LTCILKTYCH MQKFNLVSST 300
  301 YWKYPDAQHD QNQFDYLLVA HSRLHNWDAL QQQFNALFGI GKLPSIQHYG ILMYTMARIG 360
  361 ELDSVNKLYT QLLRRGMIPT YAVLQSLLYA HYKVGDFAAC FSHFELFKKY DITPSTATHT 420
  421 IMLKVYRGLN DLDGAFRILK RLSEDPSVEI TEGHFALLIQ MCCKTTNHLI AQELFNLMTE 480
  481 HYNIQHTGKS ISALMDVYIE SNRPTEAIAL FEKHSKNLSW RDGLISVYNK AIKAYIGLRN 540
  541 ANKCEELFDK ITTSKLAVNS EFYKMMIKFL VTLNEDCETA LSIIDQLIKH SVIKVDATHF 600
  601 EIIMEAYDKE GYRDGIINLY KTMSQNKVPA NSKILYYILK AVAKKSLQNN EEIKETINMV 660
  661 EDIMENAANG TLDVTYNKLH PSVMAWPMRM IV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [693-824]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KHDSPQRALE LYNRYNELFF KKHDWISNNN KFVMMRSLLV LLAQIEQWKD FETLFAKYMD  60
   61 RIENIENLPS STTPNIKLRS IFSGLFPYKV SQLIAMNKID ELPLLWKKLR EKGFILDNIS 120
  121 WNSAVEALFK DP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.874 0.055 aerobic respiration a.118.8 TPR-like

Predicted Domain #3
Region A:
Residues: [825-965]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTLSYGMKIV DDTLIHGYNL IHKFRLLTKL SEDKTQSSDK SWPTLKMKEK EPNKFQPRLY  60
   61 LKSDTYNSIM RQLDTYLDGI DDLKTLEDQV RDFISNYKYF MKDYLLMPRS KINKWEQIEM 120
  121 RHLSYFKELR KSKRVLPVSK F

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [274-626]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPIVSSDLTC ILKTYCHMQK FNLVSSTYWK YPDAQHDQNQ FDYLLVAHSR LHNWDALQQQ  60
   61 FNALFGIGKL PSIQHYGILM YTMARIGELD SVNKLYTQLL RRGMIPTYAV LQSLLYAHYK 120
  121 VGDFAACFSH FELFKKYDIT PSTATHTIML KVYRGLNDLD GAFRILKRLS EDPSVEITEG 180
  181 HFALLIQMCC KTTNHLIAQE LFNLMTEHYN IQHTGKSISA LMDVYIESNR PTEAIALFEK 240
  241 HSKNLSWRDG LISVYNKAIK AYIGLRNANK CEELFDKITT SKLAVNSEFY KMMIKFLVTL 300
  301 NEDCETALSI IDQLIKHSVI KVDATHFEII MEAYDKEGYR DGIINLYKTM SQN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.154902
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.67835748923436 bayes_pls_golite062009
binding 2.29041171814244 bayes_pls_golite062009
transcription regulator activity 1.36301889945421 bayes_pls_golite062009
nucleic acid binding 1.04482640570705 bayes_pls_golite062009
DNA binding 1.03582297487751 bayes_pls_golite062009
oxidoreductase activity 0.967526235944614 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.853542267130676 bayes_pls_golite062009
signal transducer activity 0.730941324269551 bayes_pls_golite062009
molecular transducer activity 0.730941324269551 bayes_pls_golite062009
transcription activator activity 0.628603889499786 bayes_pls_golite062009
receptor activity 0.393899879588134 bayes_pls_golite062009
transcription factor activity 0.39224150319016 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [627-807]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVPANSKILY YILKAVAKKS LQNNEEIKET INMVEDIMEN AANGTLDVTY NKLHPSVMAW  60
   61 PMRMIVKHDS PQRALELYNR YNELFFKKHD WISNNNKFVM MRSLLVLLAQ IEQWKDFETL 120
  121 FAKYMDRIEN IENLPSSTTP NIKLRSIFSG LFPYKVSQLI AMNKIDELPL LWKKLREKGF 180
  181 I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.874 a.118.8 TPR-like

Predicted Domain #6
Region A:
Residues: [808-965]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDNISWNSAV EALFKDPRTL SYGMKIVDDT LIHGYNLIHK FRLLTKLSED KTQSSDKSWP  60
   61 TLKMKEKEPN KFQPRLYLKS DTYNSIMRQL DTYLDGIDDL KTLEDQVRDF ISNYKYFMKD 120
  121 YLLMPRSKIN KWEQIEMRHL SYFKELRKSK RVLPVSKF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle