| Protein: | SHM2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 469 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SHM2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [3..468] | [12..479] |
|
|
0.0 | [1..469] | [1..469] |
|
|
0.0 | [3..468] | [12..479] |
|
|
0.0 | [1..469] | [1..470] |
|
|
0.0 | [3..469] | [4..470] |
|
|
0.0 | [3..468] | [12..478] |
|
|
0.0 | [3..468] | [12..479] |
|
Region A: Residues: [1-46] |
1 11 21 31 41 51
| | | | | |
1 MPYTLSDAHH KLITSHLVDT DPEVDSIIKD EIERQKHSID LIASEN
|
|
Region B: Residues: [320-469] |
1 11 21 31 41 51
| | | | | |
1 TQVLKNAKAL ESEFKNLGYR LVSNGTDSHM VLVSLREKGV DGARVEYICE KINIALNKNS 60
61 IPGDKSALVP GGVRIGAPAM TTRGMGEEDF HRIVQYINKA VEFAQQVQQS LPKDACRLKD 120
121 FKAKVDEGSD VLNTWKKEIY DWAGEYPLAV
|
| Detection Method: |  |
| Confidence: | 1689.0 |
| Match: | 1cj0A_ |
| Description: | Serine hydroxymethyltransferase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| L-aspartate:2-oxoglutarate aminotransferase activity | 3.359406422625 | bayes_pls_golite062009 |
| glycine dehydrogenase (decarboxylating) activity | 3.2128372762799 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor | 3.2128372762799 | bayes_pls_golite062009 |
| transferase activity | 2.59075614411581 | bayes_pls_golite062009 |
| 5-aminolevulinate synthase activity | 2.47911083054773 | bayes_pls_golite062009 |
| catalytic activity | 2.29878871754893 | bayes_pls_golite062009 |
| O-phospho-L-serine:2-oxoglutarate aminotransferase activity | 2.1692959843619 | bayes_pls_golite062009 |
| transcription regulator activity | 1.67701710033155 | bayes_pls_golite062009 |
| DNA binding | 1.4774443071095 | bayes_pls_golite062009 |
| nucleic acid binding | 1.39741122443159 | bayes_pls_golite062009 |
| transferase activity, transferring nitrogenous groups | 1.28316822767388 | bayes_pls_golite062009 |
| transaminase activity | 1.24990480711889 | bayes_pls_golite062009 |
| transferase activity, transferring acyl groups | 1.19150094103499 | bayes_pls_golite062009 |
| transcription factor activity | 1.15775909410582 | bayes_pls_golite062009 |
| N-succinyltransferase activity | 1.14675852378654 | bayes_pls_golite062009 |
| binding | 1.09053123792737 | bayes_pls_golite062009 |
| structural molecule activity | 0.754675308623467 | bayes_pls_golite062009 |
| methyltransferase activity | 0.681623261233707 | bayes_pls_golite062009 |
| vitamin binding | 0.66463470119531 | bayes_pls_golite062009 |
| protein binding | 0.613130945854863 | bayes_pls_golite062009 |
| transferase activity, transferring one-carbon groups | 0.60304280865376 | bayes_pls_golite062009 |
| L-allo-threonine aldolase activity | 0.500744432308415 | bayes_pls_golite062009 |
| glycine hydroxymethyltransferase activity | 0.271623203801431 | bayes_pls_golite062009 |
| pyridoxal phosphate binding | 0.16957228630576 | bayes_pls_golite062009 |
| vitamin B6 binding | 0.16957228630576 | bayes_pls_golite062009 |
|
Region A: Residues: [47-319] |
1 11 21 31 41 51
| | | | | |
1 FTSTSVFDAL GTPLSNKYSE GYPGARYYGG NEHIDRMEIL CQQRALKAFH VTPDKWGVNV 60
61 QTLSGSPANL QVYQAIMKPH ERLMGLYLPD GGHLSHGYAT ENRKISAVST YFESFPYRVN 120
121 PETGIIDYDT LEKNAILYRP KVLVAGTSAY CRLIDYKRMR EIADKCGAYL MVDMAHISGL 180
181 IAAGVIPSPF EYADIVTTTT HKSLRGPRGA MIFFRRGVRS INPKTGKEVL YDLENPINFS 240
241 VFPGHQGGPH NHTIAALATA LKQAATPEFK EYQ
|
| Detection Method: | |
| Confidence: | 1689.0 |
| Match: | 1cj0A_ |
| Description: | Serine hydroxymethyltransferase |
| Matching Structure (courtesy of the PDB): |
|
