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View Structure Prediction Details

Protein: NUP133
Organism: Saccharomyces cerevisiae
Length: 1157 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP133.

Description E-value Query
Range
Subject
Range
nup132 - nucleoporin Nup132
NU132_SCHPO - Nucleoporin nup132 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nup132 PE=1 SV=1
1217.0 [0..32] [1047..12]
gi|49525766 - gi|49525766|emb|CAG59385.1| unnamed protein product [Candida glabrata]
gi|50288059, gi|... - gi|50288059|ref|XP_446458.1| unnamed protein product [Candida glabrata], gi|49525766|emb|CAG59385.1|...
637.0 [0..56] [1157..43]
gi|45188089, gi|... - gi|45188089|ref|NP_984312.1| ADR216Wp [Ashbya gossypii ATCC 10895], gi|44982906|gb|AAS52136.1| ADR21...
gi|44982906 - gi|44982906|gb|AAS52136.1| ADR216Wp [Ashbya gossypii ATCC 10895]
503.0 [0..8] [1156..6]
gi|50302831, gi|... - gi|50302831|ref|XP_451352.1| unnamed protein product [Kluyveromyces lactis], gi|49640483|emb|CAH0294...
gi|49640483 - gi|49640483|emb|CAH02940.1| KLLA0A07909p [Kluyveromyces lactis]
496.0 [0..8] [1156..5]
Nup133-PA - This gene is referred to in FlyBase by the symbol Dmel\Nup133 (CG6958, FBgn0039004). It is a protein...
472.0 [0..639] [1083..733]
NUP133 - nucleoporin 133kDa
gi|157928803, gi... - gi|157928803|gb|ABW03687.1| nucleoporin 133kDa [synthetic construct], gi|123995185|gb|ABM85194.1| nu...
382.0 [0..664] [1076..723]

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Predicted Domain #1
Region A:
Residues: [1-607]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKKVHLRL RKELSVPIAV VENESLAQLS YEEESQASLM DISMEQQQLR LHSHFDNSKV  60
   61 FTENNRYIVK TLQTDYSSGF SNDDELNGYI DMQIGYGLVN DHKKVYIWNI HSTQKDTPYI 120
  121 TVPFRSDDND EIAVAPRCIL TFPATMDESP LALNPNDQDE TGGLIIIKGS KAIYYEDINS 180
  181 INNLNFKLSE KFSHELELPI NSSGGEKCDL MLNCEPAGIV LSTNMGRIFF ITIRNSMGKP 240
  241 QLKLGKLLNK PFKLGIWSKI FNTNSSVVSL RNGPILGKGT RLVYITTNKG IFQTWQLSAT 300
  301 NSHPTKLIDV NIYEAILESL QDLYPFAHGT LKIWDSHPLQ DESSQLFLSS IYDSSCNETY 360
  361 YILSTIIFDS SSNSFTIFST YRLNTFMESI TDTKFKPKIF IPQMENANDT NEVTSILVMF 420
  421 PNAVVITQVN SKLDSSYSMR RKWEDIVSLR NDIDIIGSGY DSKSLYVLTK QMGVLQFFVK 480
  481 ENEETNSKPE VGFVKSHVDQ AVYFSKINAN PIDFNLPPEI SLDQESIEHD LKLTSEEIFH 540
  541 SNGKYIPPML NTLGQHLSVR KEFFQNFLTF VAKNFNYKIS PELKLDLIEK FEILNCCIKF 600
  601 NSIIRQS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 6.44
Match: 1xksA
Description: The crystal structure of the N-terminal domain of Nup133 reveals a beta-propeller fold common to several nucleoporins
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [608-769]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVLNDIWEKT LSNYNLTQNE HLTTKTVVIN SPDVFPVIFK QFLNHVVFVL FPSQNQNFKL  60
   61 NVTNLINLCF YDGILEEGEK TIRYELLELD PMEVDTSKLP WFINFDYLNC INQCFFDFTF 120
  121 ACEEEGSLDS YKEGLLKIVK ILYYQFNQFK IWINTQPVKS VN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [770-924]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANDNFININN LYDDNHLDWN HVLCKVNLKE QCIQIAEFYK DLSGLVQTLQ TLDQNDSTTV  60
   61 SLYETFFNEF PKEFSFTLFE YLIKHKKLND LIFRFPQQHD VLIQFFQESA PKYGHVAWIQ 120
  121 QILDGSYADA MNTLKNITVD DSKKGESLSE CELHL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [925-1074]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVAKLSSLLV EKDNLDINTL RKIQYNLDTI DAEKNISNKL KKGEVQICKR FKNGSIREVF  60
   61 NILVEELKST TVVNLSDLVE LYSMLDDEES LFIPLRLLSV DGNLLNFEVK KFLNALVWRR 120
  121 IVLLNASNEG DKLLQHIVKR VFDEELPKNN 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1075-1157]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFPLPSVDLL CDKSLLTPEY ISETYGRFPI DQNAIREEIY EEISQVETLN SDNSLEIKLH  60
   61 STIGSVAKEK NYTINYETNT VEY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle