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Protein Overview: nup132

General Information:
Name(s) found: nup132 / SPAC1805.04 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • nucleoporin Nup132 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1162 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    Nup107-160 complex [IDALink to PubMed article]
    nuclear membrane [IDALink to PubMed articleLink to PubMed article]
    nuclear pore [IDALink to PubMed article][TASLink to PubMed article]
    Biological Process: cell division [IMPLink to PubMed article]
    mitotic cell cycle spindle assembly checkpoint [IMPLink to PubMed article]
    nucleocytoplasmic transport [TASLink to PubMed article]
    nuclear pore distribution [IMPLink to PubMed article]
    poly(A)+ mRNA export from nucleus [IMPLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSILGKRKN EEVVSFSPLK RISVEKSLLD STAYNNSLDW LRSKNFKVSC LLKHFNSKII  60
   61 NDHPLSGSCY TDIGYALINS RKACFILSYR QSLGTAEPPT ITFPLPEEDS NGFSGQNALT 120
  121 AFVPSDASDK EPGLLIVMPI SGRIAYWTSI GNALAQSYIC PQGMESLIKL LPKEKCEHLC 180
  181 CSNPMKFIIS TNFGRLFSVQ LRDPAGQPDV SVQLFASDIS TFSTILQKMK IFNYPSIHII 240
  241 ALKSPPLFSP YQHLLYVAEA SGLLEIYDLK LENKLVSGMN LSPIFKQVLR EGCPDASGLE 300
  301 VLDLTICPTN GNLVSFLVCW KNSINYRYMI ISLDFSDISS PSVMNIHPLY SFSSKSLESS 360
  361 KLHYSSSGNS LFVVLTDAVI IVHVQEDDKD IVSRTSWEEV IRMNTNVSGG IFMSTCYKYV 420
  421 LGKYSIPTES CFIATPYSGI AEIEVHSLEH PANNESLVKS KLEEAVFYSF LPGNPIDFSC 480
  481 NYLRSIKKPE LERIIVDLGM DILNSRSTHL PPLFASLMQH LSCRLNSLNN LVRYIRSMSL 540
  541 DVDRQVLYKL RVMGEKCNSV RYLWNTIDTE FSTVSHSLIF QRIIYRLTQS ASSDNALREW 600
  601 FLHNIESIDQ LIAQAHEFCI DSGSRVQELP LEVLDVIMEA NEVILAIQSS ALAYRRESQK 660
  661 IYKLSIDTFG EEVPWTSTPE TLVLLCRQFE LTRSALVQSH QGTSDVENTF KIKDKGVLRN 720
  721 VVSNLEVQLV ALTEVCFDAY SERIRWIEQR CGKDASEIQD VKEAFAVNRR FWVQTLSDIG 780
  781 KGSSAIRIAE KYSDYRSLVE LCYQLYEDNE LTDALNNYLD LFGIKFAFIL YDYFVENGMA 840
  841 LELLNSDRFN KSYLKQFFKS RDYNQISWMH DMRLGDYDAA SHRLLQLATK QEKLVDKKES 900
  901 ELSLSKLFLY AVPSNSGNIR DLVLVEQKLE QLHIQKMVSK SVMPVVERLR SQGKKYQLVE 960
  961 AVVDDLIGAK VAPVIARQVM QRVVKKFIAG QVVEATELLE YLSFSLYRRE DLVEGEVTDY1020
 1021 YLALRLLLTT RLTDDAKRFY ENTIWRRAVL HDNWIQVLDT QGKNDAIIET QFRMSALYRT1080
 1081 LEAVTINGLF HEGLIRPGSL SSCKFEGYDP QNLISIYPPA RFGDVTEVTK VLNRESVKLD1140
 1141 HYLTKTNLNT CYISMCLSCD TI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..455] PSI-BLAST 97.0 The crystal structure of the N-terminal domain of Nup133 reveals a beta-propeller fold common to several nucleoporins
    2 View Details [456..555] MSA 1.050992 View MSA. No confident structure predictions are available.
    3 View Details [556..622] deduced N/A No confident structure predictions are available.
    4 View Details [623..825] deduced N/A No confident structure predictions are available.
    5 View Details [826..1003] MSA 3.074977 View MSA. No confident structure predictions are available.
    6 View Details [1004..1162] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleocytoplasmic transporter activity
    		•  7.36869426424539 bayes_pls_golite062009
  • transporter activity
    		•  2.55928656852707 bayes_pls_golite062009
  • binding
    		•  2.00508289492248 bayes_pls_golite062009
  • protein binding
    		•  0.548945337973353 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle