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Protein Overview: Nup133-PA

General Information:
Name(s) found: Nup133-PA / FBpp0083695 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\Nup133 (CG6958, FBgn0039004). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18516250..18520494. It has the cytological map location 94C1. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1200 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERNLQKQLY GISRESSPGA RRYSMPAASA DSTRKSIFGG SASCAQMSGS LKRTALTNSR  60
   61 LSLSVRSTQS IAGIRSDYNS VESFGCPLPV VVNEALTFAG PGAGTVTAKV TQNGWAWVVQ 120
  121 GRRLLIWQYK DTAKSGSPPR VGKLARRGGG LAQCRELTLP YSDLGHKSDL ISVFQTEGQQ 180
  181 MASCIAVSAT GEVRYWSSIA HDGNSVDLSI LTGQEFVQLL SLPTQQGYLA VTTTCNLVFL 240
  241 RVGLTNGRYT LHHKTIKPAT SFLGGFGKKF ASILIGMNTG ADKDQTLVGM CCESNLESGE 300
  301 TIVAVLSDRA IQRWSLSNNG NTENLLYEDA DMLRRIREEF ITNFWKFRLP ADSLEIDLHL 360
  361 LDFHVVKNKA YILAGAVNAA HAPQMCYALV TGTAQAERML LESFTPLNMN KFFSAKTEED 420
  421 CLSVRFVVGS SHIYLYTSKV VYPLHLTNSV PTAELEAEKI EFHQHDDRIL SAVICSQLPL 480
  481 FFSRTHGLVS ITPGDFDGTE MMNMSSCNTP DLYAPNSCNA SFAVADHSAL TNSTNNLHLF 540
  541 ELDPDEMYNE LSDEVGQLKA AFLYHMKRNS NMVKTIVDEL LRNVTAADPS GAPMDAYKLD 600
  601 RIVITIAEDL AEDIPIADPR WEEALADQEM NRHAIGSSRS MQIINQLRDK IIAFQHFITF 660
  661 LHSSLVWDKL NVIPCGSHSL KPTGCILADI SEKIVAAMAL RSIQTKLPKL IEEAIDATVA 720
  721 LWHEEPQGSL TYQDIFYVKL SRFQNVFEAL ADIADDRIAA QNQTTISVAH FVNEINSIVL 780
  781 DVLGQVFKYR KQHASSFRLS HEKLPSYENL PWTAMAGSAG VRDTLTRLID ISVRYGSHCV 840
  841 SETELKQQLY QQIFELIDLV LDGRKTYLKS VRDTEKFNVL QQQFEAQRRE LISVLIKDRQ 900
  901 YEYAAKIAEK YLDFQSLVLI CDETQDKERL EDYTRKYEEY DFSQFAINWH LRQNRHGEVF 960
  961 ERFKGNQTAL AQFMRDHPSL GWIQLIFNGD FERAAKVLYE LAQCETEFVA RKKSMLSLAK1020
 1021 LAAFAAAESD LTAQVEKINA DLTLVEYQSQ LGHDVLESFG FDPAEQKVLK AEEIISLYIA1080
 1081 EENETASETE FRKALELLSY VEQPYDMRHK IWCAAIKRDN WTDYDPNNAV HYMQKLLFYK1140
 1141 IIEISQLMGN DSENVLPPME DFLESVELGD LPQQKPFQYL LKLTYEYVAD MFKQPDDMEL1200
 1201

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..536] PSI-BLAST 121.0 The crystal structure of the N-terminal domain of Nup133 reveals a beta-propeller fold common to several nucleoporins
    2 View Details [537..671] MSA 2.068995 View MSA. No confident structure predictions are available.
    3 View Details [672..862] MSA 1.07699 View MSA. No confident structure predictions are available.
    4 View Details [863..938] deduced N/A No confident structure predictions are available.
    5 View Details [939..1101] MSA 2.080982 View MSA. No confident structure predictions are available.
    6 View Details [1102..1200] MSA 1.076985 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleocytoplasmic transporter activity
    		•  7.36869426424539 bayes_pls_golite062009
  • transporter activity
    		•  2.55928656852707 bayes_pls_golite062009
  • binding
    		•  1.5683135853172 bayes_pls_golite062009
  • protein binding
    		•  0.571876690720183 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle