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View Structure Prediction Details

Protein: DAL80
Organism: Saccharomyces cerevisiae
Length: 269 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DAL80.

Description E-value Query
Range
Subject
Range
gi|190409853 - gi|190409853|gb|EDV13118.1| GATA family transcriptional repressor [Saccharomyces cerevisiae RM11-1a]
gi|207343384 - gi|207343384|gb|EDZ70855.1| YKR034Wp-like protein [Saccharomyces cerevisiae AWRI1631]
DAL80_YEAST - Nitrogen regulatory protein DAL80 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DAL80 ...
DAL80 - Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by ni...
5.0E-67 [1..269] [1..269]
GAT5B_XENLA - GATA-binding factor 5-B OS=Xenopus laevis GN=gata5-b PE=2 SV=1
3.0E-43 [1..216] [154..384]
gi|5882288 - gi|5882288|gb|AAD55267.1|AF179425_1 transcription factor GATA-6 [Mus musculus]
3.0E-41 [9..216] [216..439]
GATA6_RAT, GAT6_RAT - Transcription factor GATA-6 - Rattus norvegicus (Rat), (P46153) Transcription factor GATA-6 (GATA bi...
5.0E-40 [3..216] [210..437]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLSDSLKLP SPTLSAAAGV DDCDGEDHPT CQNCFTVKTP LWRRDEHGTV LCNACGLFLK  60
   61 LHGEPRPISL KTDTIKSRNR KKLNNNNVNT NANTH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 176.08661
Match: 4gatA_
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.00967542385368 bayes_pls_golite062009
binding 3.53535874483763 bayes_pls_golite062009
DNA binding 3.36252792779457 bayes_pls_golite062009
nucleic acid binding 3.05528938535257 bayes_pls_golite062009
transcription factor activity 2.70303114587416 bayes_pls_golite062009
transcription activator activity 1.62405765585032 bayes_pls_golite062009
sequence-specific DNA binding 1.5397618957429 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.50210964370113 bayes_pls_golite062009
transcription factor binding 1.38523780690867 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.37025623768659 bayes_pls_golite062009
protein binding 1.29473277650963 bayes_pls_golite062009
transcription cofactor activity 0.58115018700114 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.57492522309817 bayes_pls_golite062009
transcription repressor activity 0.256420113528322 bayes_pls_golite062009
catalytic activity 0.101795606736461 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [96-269]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNDPNKIFKR KKRLLTTGGG SLPTNNPKVS ILEKFMVSGS IKPLLKPKET VPNTKECSTQ  60
   61 RGKFSLDPCE PSGKNYLYQI NGSDIYTSNI ELTRLPNLST LLEPSPFSDS AVPEIELTWK 120
  121 LHNEEEVIKL KTKISELELV TDLYKKHIFQ LNEKCKQLEV ELHSRASVQS HPQH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle