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View Structure Prediction Details

Protein: YJU2
Organism: Saccharomyces cerevisiae
Length: 278 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJU2.

Description E-value Query
Range
Subject
Range
gi|190409737 - gi|190409737|gb|EDV13002.1| 32.3 kDa protein in CWP1-MBR1 intergenic region [Saccharomyces cerevisia...
YJU2 - Essential protein required for pre-mRNA splicing; associates transiently with the spliceosomal NTC (...
gi|207343551 - gi|207343551|gb|EDZ70985.1| YKL095Wp-like protein [Saccharomyces cerevisiae AWRI1631]
CWC16_YEAST - Protein CWC16 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YJU2 PE=1 SV=1
1.0E-97 [1..278] [1..278]
CC130_MOUSE - Coiled-coil domain-containing protein 130 OS=Mus musculus GN=Ccdc130 PE=2 SV=1
5.0E-74 [1..213] [1..213]
CCDC130 - coiled-coil domain containing 130
1.0E-73 [1..214] [1..214]
CE01697 - YJU2 protein status:Partially_confirmed UniProt:Q09651 protein_id:CAA87435.1
1.0E-63 [1..208] [1..207]
gi|15222627, gi|... - gi|62320731|dbj|BAD95398.1| hypothetical protein [Arabidopsis thaliana], gi|44681478|gb|AAS47679.1| ...
1.0E-61 [1..208] [4..209]

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Predicted Domain #1
Region A:
Residues: [1-212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSERKAINKY YPPDYNPLEA EKLSRKMAKK LKTMNKSHAS IRLMTPFSMR CLECNEYIPK  60
   61 SRKFNGKKEL LKEKYLDSIK IYRLTISCPR CANSIAFRTD PGNSDYVMEV GGVRNYVPQK 120
  121 PNDDLNAKTA VESIDETLQR LVREKEMEQN EKMGIKEQAD DKMDLLEKRL AKIQQEQEDD 180
  181 EELENLRKKN LEMSQRAEMI NRSKHAQQEK AV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.74510263950241 bayes_pls_golite062009
DNA binding 2.44566855074341 bayes_pls_golite062009
binding 2.27558039325716 bayes_pls_golite062009
nucleic acid binding 2.24669580094588 bayes_pls_golite062009
transcription factor activity 1.9022303099625 bayes_pls_golite062009
sequence-specific DNA binding 0.911347670379084 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.839985608194026 bayes_pls_golite062009
transcription activator activity 0.685318320359585 bayes_pls_golite062009
protein binding 0.606784236996154 bayes_pls_golite062009
transcription factor binding 0.50605454225389 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 0.296219659608347 bayes_pls_golite062009
catalytic activity 0.133319360419662 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [213-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTDDLDNLVD QVFDNHRQRT NKPGNNNDEK RTPLFNPTST KGKIQKKSSV RTNPLGIVIK  60
   61 RGKSLK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle