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View Structure Prediction Details

Protein: TMA19
Organism: Saccharomyces cerevisiae
Length: 167 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TMA19.

Description E-value Query
Range		 Subject
Range
TPT1 - tumor protein, translationally-controlled 1
gi|73989031, gi|... - gi|73989037|ref|XP_856566.1| PREDICTED: similar to Translationally controlled tumor protein (TCTP) (...
gi|146741438 - gi|146741438|dbj|BAF62375.1| tumor protein, translationally-controlled 1 [Pan troglodytes verus]
TCTP_PANTR - Translationally-controlled tumor protein OS=Pan troglodytes GN=TPT1 PE=2 SV=1
gi|90075140 - gi|90075140|dbj|BAE87250.1| unnamed protein product [Macaca fascicularis]
ENSMMUT000000323... - null, null
tr|M3VXX1|M3VXX1... - Tumor protein, translationally-controlled 1 OS=Felis catus GN=TPT1 PE=3 SV=1
TCTP_PIG - Translationally-controlled tumor protein OS=Sus scrofa GN=TPT1 PE=2 SV=1
 6.0E-72 [1..166] [1..171]
TCTP_RABIT - Translationally-controlled tumor protein OS=Oryctolagus cuniculus GN=TPT1 PE=2 SV=2
 8.0E-71 [1..166] [1..171]
gi|51859243 - gb|AAH82190.1| MGC98697 protein [Xenopus laevis]
TCTP_RAT - Translationally-controlled tumor protein OS=Rattus norvegicus GN=Tpt1 PE=1 SV=1
TCTP_MOUSE - Translationally-controlled tumor protein OS=Mus musculus GN=Tpt1 PE=1 SV=1
 9.0E-70 [1..166] [1..171]
TCTP_CHICK - Translationally-controlled tumor protein homolog OS=Gallus gallus GN=TPT1 PE=2 SV=1
 1.0E-69 [1..166] [1..171]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 2.0E-68 [1..166] [1..171]
TCTP_DANRE - Translationally-controlled tumor protein homolog OS=Danio rerio GN=tpt1 PE=2 SV=1
 2.0E-64 [1..166] [1..170]
TCTP_LABRO - Translationally-controlled tumor protein homolog OS=Labeo rohita GN=tpt1 PE=2 SV=1
 2.0E-62 [1..166] [1..170]
TCTP_HEVBR - Translationally-controlled tumor protein homolog OS=Hevea brasiliensis GN=TCTP PE=2 SV=1
 3.0E-61 [1..166] [1..167]

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Predicted Domain #1
Region A:
Residues: [1-167] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIIYKDIFSN DELLSDAYDA KLVDDVIYEA DCAMVNVGGD NIDIGANPSA EGGDDDVEEG  60
   61 AEMVNNVVHS FRLQQTAFDK KSFLTYIKGY MKAVKAKLQE TNPEEVPKFE KGAQTYVKKV 120
  121 IGSFKDWEFF TGESMDPDAM VVMLNYREDG TTPFVAIWKH GIVEEKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 598.39794
Match: 1h7yA_
Description: Translationally controlled tumor-associated protein tctp, p23fyp
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on sulfur group of donors 3.4377744251418 bayes_pls_golite062009
protein-methionine-R-oxide reductase activity 3.14392283789517 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor 2.6167603393936 bayes_pls_golite062009
binding 2.26574571365153 bayes_pls_golite062009
transition metal ion binding 1.89566171684057 bayes_pls_golite062009
cation binding 1.8695053562775 bayes_pls_golite062009
metal ion binding 1.8695053562775 bayes_pls_golite062009
ion binding 1.86234474080078 bayes_pls_golite062009
nucleic acid binding 1.14994807703391 bayes_pls_golite062009
transcription regulator activity 1.009242671721 bayes_pls_golite062009
DNA binding 0.841663070276259 bayes_pls_golite062009
catalytic activity 0.566791077255496 bayes_pls_golite062009
protein binding 0.327945052023132 bayes_pls_golite062009
transcription factor activity 0.202907039530709 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle