| Protein: | BIR1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 954 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BIR1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..954] | [1..954] |
|
|
1.0E-97 | [187..876] | [4498..5191] |
|
|
1.0E-61 | [215..929] | [3899..4666] |
|
|
1.0E-47 | [146..703] | [46..621] |
|
|
2.0E-38 | [244..743] | [669..1113] |
|
|
1.0E-31 | [133..649] | [1369..1860] |
|
|
1.0E-30 | [217..522] | [343..658] |
|
|
1.0E-29 | [130..647] | [710..1210] |
|
Region A: Residues: [1-128] |
1 11 21 31 41 51
| | | | | |
1 MDGQIDKMEK RYSMTKLENR LRTFQDGVAL EKKKLKWSFK VIPYQAMAKL GFYFDPVIDP 60
61 KTSKLKKDSV RCCYCHRQTY NVRDCRSKRK DVLETLSNIM RQHLTVTDNK QVCLLIYLRN 120
121 KLLTDYSF
|
| Detection Method: |  |
| Confidence: | 15.259637 |
| Match: | PF00653 |
| Description: | Inhibitor of Apoptosis domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| tubulin binding | 4.57400254300037 | bayes_pls_golite062009 |
| microtubule binding | 4.57357620081095 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.48621854589316 | bayes_pls_golite062009 |
| binding | 2.74298177825814 | bayes_pls_golite062009 |
| protein binding | 1.64791933694023 | bayes_pls_golite062009 |
| caspase inhibitor activity | 1.09294960695843 | bayes_pls_golite062009 |
| caspase regulator activity | 0.942292562752374 | bayes_pls_golite062009 |
| cysteine-type endopeptidase inhibitor activity | 0.583383774635169 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 0.395686831458354 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 0.317066727620117 | bayes_pls_golite062009 |
|
Region A: Residues: [129-280] |
1 11 21 31 41 51
| | | | | |
1 HMGVSDWKND KYFSNPDDEN VINLRKFTFQ DNWPHSGSQN EHPLGIEKMV NAGLMRYDSS 60
61 IEGLGDPSMD KTLMNDTCYC IYCKQLLQGW SINDDPMSRH YKVSQNGNCY FFQTRNRFER 120
121 IKNDNDSITK NCEVSPTLGE NGKREVINTK TA
|
| Detection Method: | |
| Confidence: | 14.83 |
| Match: | 1e31A |
| Description: | Anti-apoptotic protein survivin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [281-635] |
1 11 21 31 41 51
| | | | | |
1 SQRQCPLFES PPSSTGPQLD DYNEKTDISV IQHNISVLDG AQGENVKRNS VEEKEQINME 60
61 NGSTTLEEGN INRDVLADKK EVISTPTAKE IKRPNVQLTQ SSSPIKKKRK FKRISPRKIF 120
121 DEEDSEHSLN NNSANGDNKD KDLVIDFTSH IIKNRDVGRK NAILDDSTDE FSFSNQGHNT 180
181 FDIPIPTSSH LLKGIDSDND NVIREDDTGI NTDTKGASSK HEKFSVNSEE DLNFSEVKLT 240
241 GRDSSTNILI RTQIVDQNLG DIDRDKVPNG GSPEVPKTHE LIRDNSEKRE AQNGEFRHQK 300
301 DSTVRQSPDI LHSNKSGDNS SNITAIPKEE QRRGNSKTSS IPADIHPKPR KNLQE
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [636-737] |
1 11 21 31 41 51
| | | | | |
1 PRSLSISGKV VPTERKLDNI NIDLNFSASD FSPSSQSEQS SKSSSVISTP VASPKINLTR 60
61 SLHAVKELSG LKKETDDGKY FTNKQETIKI LEDVSVKNET PN
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [738-954] |
1 11 21 31 41 51
| | | | | |
1 NEMLLFETGT PIASQENKSR KLFDEEFSGK ELDIPIDSST VEIKKVIKPE FEPVPSVARN 60
61 LVSGTSSYPR NSRLEEQRKE TSTSLADNSK KGSSFNEGNN EKEPNAAEWF KIDENRHLVK 120
121 NYFHDLLKYI NNNDATLAND KDGDLAFLIK QMPAEELDMT FNNWVNLKVQ SIKREFIDDC 180
181 DKKLDILRRD YYTATNFIET LEDDNQLIDI AKKMGIL
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
