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View Structure Prediction Details

Protein: SWI3
Organism: Saccharomyces cerevisiae
Length: 825 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SWI3.

Description E-value Query
Range
Subject
Range
SWI3 - Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chr...
SWI3_YEAST - SWI/SNF complex subunit SWI3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SWI3 PE=1 S...
0.0 [1..825] [1..825]
ssr2 - SWI /SNF and RSC complex subunit Ssr2
SSR2_SCHPO - SWI/SNF and RSC complexes subunit ssr2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ssr...
0.0 [299..739] [12..455]
SWI3C_ARATH - SWI/SNF complex subunit SWI3C OS=Arabidopsis thaliana GN=SWI3C PE=1 SV=1
4.0E-95 [149..726] [2..652]
gi|6678027, gi|1... - pir||T30967 transcription activator SRG3 - mouse, gi|6678027|ref|NP_033237.1| SWI/SNF related, matr...
4.0E-92 [83..714] [245..809]
gi|32880191, gi|... - gi|32880191|gb|AAP88926.1| SWI/SNF related, matrix associated, actin dependent regulator of chromati...
gi|60654775 - gi|60654775|gb|AAX31952.1| SWI/SNF related matrix associated actin-dependent regulator of chromatin ...
4.0E-90 [83..668] [220..762]
psa-1 - SWI\/SNF protein status:Confirmed UniProt:Q9U2W6 protein_id:CAB54337.2
4.0E-88 [228..742] [3..535]
gi|4220848 - gi|4220848|gb|AAD12718.1| moira [Drosophila melanogaster]
4.0E-77 [89..660] [214..757]

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Predicted Domain #1
Region A:
Residues: [1-6]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENTLG

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [229-308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSSVANTPSE IPDAHKAEQE DIIEKTESVD KKVDSGEERN EQEREIMNDH SKSANPKKTT  60
   61 ITRVEPETFE IPQAHEIVIP 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.29
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #2
Region A:
Residues: [7-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGSTVNASVD VDQHGNDNNS DSNANAAVAG VANTDTAGEE SQQQDESLKD EATVPNTRDA  60
   61 ESEAITVTAK QQP

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.29
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #3
Region A:
Residues: [80-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TMQANKLDSQ ETPSTEESRA QNVFGQDNED SDNLFGETES SVSNNEANTP SIPTNPVDNE  60
   61 NNKPAIKEDS TIQDSNGDV

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.29
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #4
Region A:
Residues: [159-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNMEDVKIQK EEEPENNTVI EGVKEESQPD ENTKEMDEVE EDDEDDDQPM ISPDNSIFGD  60
   61 TKSESKQLGN 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.29
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #5
Region A:
Residues: [309-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYSKWFNLEK IHSIEVQSLP EFFTNRIPSK TPEVYMRYRN FMVNSYRLNP NEYFSVTTAR  60
   61 RNVSGDAAAL FRLHKFLTKW GLINYQVDSK LLPKNIEPPL T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.642 a.118.9 ENTH/VHS domain
View Download 0.567 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.522 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.478 a.4.5 "Winged helix" DNA-binding domain
View Download 0.440 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.382 c.1.8 (Trans)glycosidases
View Download 0.359 a.142.1 PTS-regulatory domain, PRD
View Download 0.341 c.55.4 Translational machinery components
View Download 0.336 a.11.2 Second domain of FERM
View Download 0.334 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.328 d.54.1 Enolase N-terminal domain-like
View Download 0.322 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.313 a.85.1 Hemocyanin, N-terminal domain
View Download 0.309 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.306 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.304 c.46.1 Rhodanese/Cell cycle control phosphatase
View Download 0.290 c.55.1 Actin-like ATPase domain
View Download 0.285 d.56.1 GroEL-intermediate domain like
View Download 0.279 c.55.4 Translational machinery components
View Download 0.277 d.68.4 YhbY-like
View Download 0.276 d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.274 c.3.1 FAD/NAD(P)-binding domain
View Download 0.269 a.28.2 Colicin E immunity proteins
View Download 0.265 d.58.49 YajQ-like
View Download 0.262 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.249 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.247 a.118.1 ARM repeat
View Download 0.246 c.50.1 Macro domain-like
View Download 0.239 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.236 a.4.5 "Winged helix" DNA-binding domain
View Download 0.235 a.4.5 "Winged helix" DNA-binding domain
View Download 0.234 a.74.1 Cyclin-like
View Download 0.233 c.78.2 Aspartate/glutamate racemase
View Download 0.231 a.118.1 ARM repeat
View Download 0.222 a.70.1 N-terminal domain of the delta subunit of the F1F0-ATP synthase
View Download 0.220 a.4.5 "Winged helix" DNA-binding domain
View Download 0.217 d.164.1 SMAD MH1 domain
View Download 0.212 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.209 c.10.1 RNI-like
View Download 0.207 a.118.1 ARM repeat

Predicted Domain #6
Region A:
Residues: [410-485]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQYSTRHDAP RGLFPFESYK PSVQLPDMAK LKKMMNTSDS ESTLYKYLKE SKRKYDEITH  60
   61 PPSTTDDENG DKNDNG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.154902
Match: 1h8qA_
Description: No description for 1h8qA_ was found.

Predicted Domain #7
Region A:
Residues: [486-596]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKMNNEVSTS TSMTGDANLL EEGETSRPLK KVKILEQIDE NWSKEDLQKL LKGIQEFGAD  60
   61 WYKVAKNVGN KSPEQCILRF LQLPIEDKFL YGDGNGKGDN DNGLGPLKYA P

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.36
Match: 1h88C
Description: c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [597-825]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HLPFSKSENP VLSTIAFLVG LVNPKTVQSM TQRAIQSAES IKSQKEEISD QKPIEHIKEG  60
   61 SEIAISSLGY RSHIFATNEE RQMNFLTNEL IRLQMEKLDA KLNHLKKLEK FMELERKTLE 120
  121 RQQENLLIQR LNFNQNSSKI VNVLSKCLNL ISDSNINNSS VAEKEEIRSQ IDHFKSMLSK 180
  181 PETLSIGKNP FNKPNIETGE NHNGQSISNE NDVKPISIEA PQFYRYWSA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle