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View Structure Prediction Details

Protein: YIL172C, FSP2
Organism: Saccharomyces cerevisiae
Length: 589 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIL172C, FSP2.

Description E-value Query
Range
Subject
Range
YGR287C - Isomaltase (alpha-D-glucosidase); may interact with ribosomes, based on co-purification experiments;...
MALX3_YEAST - Oligo-1,6-glucosidase IMA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IMA1 PE=1 SV=...
0.0 [1..589] [1..589]
O16G_GEOTM - Oligo-1,6-glucosidase OS=Geobacillus thermoglucosidasius GN=malL PE=1 SV=1
0.0 [14..588] [5..559]
O16G_BACCE - Oligo-1,6-glucosidase OS=Bacillus cereus GN=malL PE=1 SV=1
0.0 [11..589] [2..558]
gi|8096681 - gi|8096681|gb|AAF71997.1|AF216220_1 alpha-glucosidase [Bacillus sp. DG0303]
0.0 [12..588] [3..559]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..588] [5..583]
gi|580824 - gi|580824|emb|CAA54266.1| alpha-glucosidase [Bacillus sp.]
0.0 [1..588] [5..583]

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Predicted Domain #1
Region A:
Residues: [1-302]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTISSAHPET EPKWWKEATI YQIYPASFKD SNNDGWGDMK GIASKLEYIK ELGTDAIWIS  60
   61 PFYDSPQDDM GYDIANYEKV WPTYGTNEDC FALIEKTHKL GMKFITDLVI NHCSSEHEWF 120
  121 KESRSSKTNP KRDWFFWRPP KGYDAEGKPI PPNNWRSYFG GSAWTFDEKT QEFYLRLFCS 180
  181 TQPDLNWENE DCRKAIYESA VGYWLDHGVD GFRIDVGSLY SKVAGLPDAP VIDENSKWQL 240
  241 SDPFTMNGPR IHEFHQEMNK FIRNRVKDGR EIMTVGEMRH ATDETKRLYT SASRHELSEL 300
  301 FN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2160.0
Match: 1uok__
Description: Oligo-1,6-glucosidase; Oligo-1,6, glucosidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, hydrolyzing O-glycosyl compounds 5.72449317118946 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 5.38610972475995 bayes_pls_golite062009
hydrolase activity 4.42755848458375 bayes_pls_golite062009
hexosaminidase activity 2.6383220379017 bayes_pls_golite062009
chitinase activity 2.45357334610104 bayes_pls_golite062009
structural molecule activity 2.28030619331997 bayes_pls_golite062009
beta-N-acetylhexosaminidase activity 2.12259271877403 bayes_pls_golite062009
trehalase activity 2.11042620996316 bayes_pls_golite062009
alpha-amylase activity 2.09193270404736 bayes_pls_golite062009
amylase activity 2.03484942782894 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
glucosidase activity 1.63850753281742 bayes_pls_golite062009
transporter activity 1.28975867300692 bayes_pls_golite062009
organic acid transmembrane transporter activity 1.09355005521552 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 1.08320932161637 bayes_pls_golite062009
transmembrane transporter activity 1.06875155491269 bayes_pls_golite062009
substrate-specific transporter activity 0.798668027833638 bayes_pls_golite062009
amine transmembrane transporter activity 0.726290283967376 bayes_pls_golite062009
galactosidase activity 0.67508380605029 bayes_pls_golite062009
binding 0.63693798355947 bayes_pls_golite062009
alpha-glucosidase activity 0.54694531123812 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.543615761700598 bayes_pls_golite062009
carbohydrate binding 0.4998423581103 bayes_pls_golite062009
maltase activity 0.442635030512661 bayes_pls_golite062009
sugar binding 0.36459095255871 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.266938437560648 bayes_pls_golite062009
active transmembrane transporter activity 0.247544462005515 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [303-589]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSHTDVGTSP KFRQNLIPYE LKDWKVALAE LFRYVNGTDC WSTIYLENHD QPRSITRFGD  60
   61 DSPKNRVISG KLLSVLLVSL SGTLYVYQGQ ELGEINFKNW PIEKYEDVEV RNNYDAIKEE 120
  121 HGENSKEMKR FLEAIALISR DHARTPMQWS REEPNAGFSG PNAKPWFYLN ESFREGINAE 180
  181 DESKDPNSVL NFWKEALRFR KAHKDITVYG YDFEFIDLDN KKLFSFTKKY DNKTLFAALN 240
  241 FSSDSIDFTI PNNSSSFKLE FGNYPRSEVD ASSRTLKPWE GRIYISE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2160.0
Match: 1uok__
Description: Oligo-1,6-glucosidase; Oligo-1,6, glucosidase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle