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View Structure Prediction Details

Protein: YRB2
Organism: Saccharomyces cerevisiae
Length: 327 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YRB2.

Description E-value Query
Range
Subject
Range
RGPD6, RGPD5, RGPD8 - RANBP2-like and GRIP domain containing 8, RANBP2-like and GRIP domain containing 6, RANBP2-like and ...
2.0E-74 [2..325] [1134..1464]
RBP2_MOUSE - E3 SUMO-protein ligase RanBP2 OS=Mus musculus GN=Ranbp2 PE=1 SV=1
5.0E-74 [2..325] [1947..2277]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
1.0E-72 [2..325] [2110..2440]
RBP2_BOVIN - E3 SUMO-protein ligase RanBP2 (Fragment) OS=Bos taurus GN=RANBP2 PE=2 SV=2
6.0E-65 [17..325] [1..305]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-60 [2..297] [963..1265]
YRB2 - Protein of unknown function involved in nuclear processes of the Ran-GTPase cycle; involved in nucle...
YRB2_YEAST - Ran-specific GTPase-activating protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...
5.0E-48 [1..327] [1..327]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSETNGGNAA RENSEVKQTA VENPIDKLDG TPKRPREKDQ DEQAEETSDK SEAPNKNDEE  60
   61 KKEEGKKDQE PSHKKIKVDD GKTVESGIVE DDKKEDKFVF GAASKFGTGF GVA

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.87
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #2
Region A:
Residues: [114-189]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKDTKDGDAT TSTESLPASD SKTKKPFAFG SGLSFGSGFN ILKNKTENNS ESEKKATDVD  60
   61 KDKVHSGSEQ LANASE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.87
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted functions:

Term Confidence Notes
binding 3.29080729281876 bayes_pls_golite062009
protein binding 2.12168271674167 bayes_pls_golite062009
transcription regulator activity 2.10584700564436 bayes_pls_golite062009
nucleic acid binding 1.85794418941003 bayes_pls_golite062009
DNA binding 1.77960272183811 bayes_pls_golite062009
transporter activity 1.28986800087234 bayes_pls_golite062009
molecular transducer activity 1.15625292719687 bayes_pls_golite062009
signal transducer activity 1.15625292719687 bayes_pls_golite062009
Ran GTPase binding 1.07023555877478 bayes_pls_golite062009
substrate-specific transporter activity 0.79883446648737 bayes_pls_golite062009
cytoskeletal protein binding 0.74133713912741 bayes_pls_golite062009
actin binding 0.57235223545021 bayes_pls_golite062009
receptor activity 0.369903612832044 bayes_pls_golite062009
histone binding 0.359498460253937 bayes_pls_golite062009
protein domain specific binding 0.18356841109571 bayes_pls_golite062009
transmembrane receptor activity 0.159652062741581 bayes_pls_golite062009
pyrophosphatase activity 0.0611639610381174 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0524559849408587 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0498422520006935 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [190-327]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTKDKPKPLK LQKQEVKSGE ESEECIYQVN AKLYQLSNIK EGWKERGVGI IKINKSKDDV  60
   61 EKTRIVMRSR GILKVILNIQ LVKGFTVQKG FTGSLQSEKF IRLLAVDDNG DPAQYAIKTG 120
  121 KKETTDELYN IIVKSVPK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 105.39794
Match: 1rrpB_
Description: Nuclear pore complex protein Nup358
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle