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View Structure Prediction Details

Protein: MAL13
Organism: Saccharomyces cerevisiae
Length: 473 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAL13.

Description E-value Query
Range
Subject
Range
gi|3881 - gi|3881|emb|CAA33319.1| unnamed protein product [Saccharomyces cerevisiae]
gi|151946690 - gi|151946690|gb|EDN64911.1| MAL-activator protein [Saccharomyces cerevisiae YJM789]
0.0 [9..473] [4..470]
gi|171885|gb|AAA... - maltose activator protein (MAL63)
gi|171885 - gi|171885|gb|AAA34755.1| maltose activator protein (MAL63)
ID=asmbl_4865|m.3169 - ID=asmbl_4865|g.3169 ORF ID=asmbl_4865|g.3169 ID=asmbl_4865|m.3169 type:complete len:471 (+) ID=asm...
0.0 [9..473] [4..470]

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Predicted Domain #1
Region A:
Residues: [1-73]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLTKQTCAK QACDCCRIRR VKCDGKRPCS SCLQNSLDCT YLQPSRKRGP KSIRLRSLKR  60
   61 IAEVQRESGP NTI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.09691
Match: 1zmeC_
Description: PUT3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.56444258780502 bayes_pls_golite062009
DNA binding 4.26146437716972 bayes_pls_golite062009
nucleic acid binding 4.17369933547911 bayes_pls_golite062009
transcription factor activity 3.049435548132 bayes_pls_golite062009
binding 2.91929847152301 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.03201524223606 bayes_pls_golite062009
sequence-specific DNA binding 1.87955444697212 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.86200506906385 bayes_pls_golite062009
transcription activator activity 0.915626626047549 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [74-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATAPVIYKRV PKKLIDQCLR LYHDNLYVIW PLLSYDDLHK LLEEKYNDNY VYWFLTALSA  60
   61 ATLSDLQTEI KSEEEVTFTG KQLSNLCISS CQQFDDLDNS NIFNIMTYYC LHRSFAQISN 120
  121 ARTSYRLCCE AVGLITVAGL HREETYGSLT FEEQQLRRKL YYLLLMTERY YAIYLHCATS 180
  181 LDATIAPPQL ELVTDPQLSM DSFLEMIRVF TVPGKCFFDA LAADSTDASC TEESLKKIWN 240
  241 ELHTTSSEIE PWSNGYIDIS FSRHWIRILA WKLAYQMRG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [353-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNFSLNANNG QIPIEIARDM LIDTYLTPEN LYDVHGPGVP VKTLEIATAL VDIVGQYDHN  60
   61 MKLEAWNVLH DVCKFAFSLN HYNNDMLKRF STKCQNALIT LPISKPLQLD GYPKDNEDID 120
  121 P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.731 a.74.1 Cyclin-like
View Download 0.715 a.118.8 TPR-like
View Download 0.606 a.66.1 Transducin (alpha subunit), insertion domain
View Download 0.735 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.735 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.731 a.74.1 Cyclin-like
View Download 0.715 a.118.8 TPR-like
View Download 0.695 a.74.1 Cyclin-like
View Download 0.606 a.66.1 Transducin (alpha subunit), insertion domain
View Download 0.602 e.20.1 Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment
View Download 0.476 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.426 a.85.1 Hemocyanin, N-terminal domain
View Download 0.387 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.380 c.30.1 PreATP-grasp domain
View Download 0.380 a.24.4 Hemerythrin
View Download 0.378 f.1.3 delta-Endotoxin (insectocide), N-terminal domain
View Download 0.377 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.362 a.92.1 Carbamoyl phosphate synthetase, large subunit connection domain
View Download 0.361 a.118.8 TPR-like
View Download 0.359 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.353 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.343 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.342 a.29.4 RecG, N-terminal domain
View Download 0.341 a.1.1 Globin-like
View Download 0.339 a.24.17 Group V grass pollen allergen
View Download 0.334 d.58.26 GHMP Kinase, C-terminal domain
View Download 0.333 a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View Download 0.331 d.95.2 Homing endonucleases
View Download 0.317 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.311 a.4.1 Homeodomain-like
View Download 0.310 d.189.1 PX domain
View Download 0.303 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.285 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.265 c.30.1 PreATP-grasp domain
View Download 0.260 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.259 d.95.2 Homing endonucleases
View Download 0.254 d.17.4 NTF2-like
View Download 0.248 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.243 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.243 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.242 a.74.1 Cyclin-like
View Download 0.240 c.78.2 Aspartate/glutamate racemase
View Download 0.239 a.7.6 Ribosomal protein S20
View Download 0.239 a.72.1 Functional domain of the splicing factor Prp18
View Download 0.238 c.10.1 RNI-like
View Download 0.237 a.74.1 Cyclin-like
View Download 0.237 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.231 a.29.2 Bromodomain
View Download 0.229 a.24.3 Cytochromes
View Download 0.228 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.223 d.89.1 Origin of replication-binding domain, RBD-like
View Download 0.213 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.208 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.206 a.118.15 Aconitase B, N-terminal domain
View Download 0.206 a.47.2 t-snare proteins
View Download 0.204 a.72.1 Functional domain of the splicing factor Prp18
View Download 0.200 d.150.1 4'-phosphopantetheinyl transferase


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