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View Structure Prediction Details

Protein: YGR283C
Organism: Saccharomyces cerevisiae
Length: 341 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGR283C.

Description E-value Query
Range
Subject
Range
YG5X_YEAST - Putative methyltransferase YGR283C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YGR28...
YGR283C - Protein of unknown function; may interact with ribosomes, based on co-purification experiments; pred...
0.0 [1..341] [1..341]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [2..337] [62..378]
CG12128-PA - This gene is referred to in FlyBase by the symbol Dmel\CG12128 (CG12128, FBgn0033473). It is a prote...
2.0E-82 [1..327] [33..361]
YGWG_SCHPO - Putative methyltransferase SPBC8D2.16c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pi0...
SPBC8D2.16c - DUF171 family protein
5.0E-57 [33..264] [11..253]
gi|18314060, gi|... - gi|18314060|ref|NP_560727.1| hypothetical protein PAE3431 [Pyrobaculum aerophilum str. IM2], gi|1816...
3.0E-52 [40..336] [2..257]
gi|5457775, gi|7... - pir||B75148 hypothetical protein PAB2119 - Pyrococcus abyssi (strain Orsay), gi|5457775|emb|CAB49265...
gi|5457775, gi|1... - gi|5457775|emb|CAB49265.1| Hypothetical protein [Pyrococcus abyssi GE5], gi|14520559|ref|NP_126034.1...
4.0E-50 [42..336] [5..252]
gi|7429565 - pir||B71188 hypothetical protein PH1779 - Pyrococcus horikoshii
gi|14591536, gi|... - gi|3258214|dbj|BAA30897.1| 258aa long hypothetical protein [Pyrococcus horikoshii OT3], gi|14591536|...
3.0E-49 [42..336] [5..252]
gi|18978198, gi|... - gi|18978198|ref|NP_579555.1| hypothetical protein PF1826 [Pyrococcus furiosus DSM 3638], gi|18894007...
7.0E-49 [42..336] [5..252]

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Predicted Domain #1
Region A:
Residues: [1-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVKHKSESL KHEEGAAKKA KTGLLKLKKI MDIESNVVKY SICIPTTVID NCNNLEQVTF  60
   61 TAYQIARTAV LFNVQEIIVL DQSKDKKHEK KSRSKETISD CLLLATLLQY 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [218-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGYHVRMAST LNEVSEGYTK IVWVNSGDFH YDEELSKYHK VETKLPYIAK LKKSSTSEKP  60
   61 CNILLIFGKW GHLKRCFRRS DLESSSLHHY FSGQLQFPAS VPQGNIPIQD SLPIALTMFQ 120
  121 RWAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.39794
Match: 1k3rA_
Description: Hypothetical protein MTH1 (MT0001), insert domain; Hypothetical protein MTH1 (MT0001), dimerisation domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of ribosome 6.10995066483033 bayes_pls_golite062009
structural molecule activity 5.55926301079047 bayes_pls_golite062009
RNA methyltransferase activity 3.05692269334609 bayes_pls_golite062009
methyltransferase activity 1.82347727012845 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 1.75463745431819 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 1.28709139538479 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.27646201386283 bayes_pls_golite062009
RNA binding 1.26793351043713 bayes_pls_golite062009
exoribonuclease activity 1.22883489365565 bayes_pls_golite062009
DNA binding 1.03854786806734 bayes_pls_golite062009
binding 1.0385094021694 bayes_pls_golite062009
3'-5' exonuclease activity 1.03810655279652 bayes_pls_golite062009
ribonuclease activity 1.02104056959293 bayes_pls_golite062009
rRNA methyltransferase activity 0.991198550579488 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.98640864840845 bayes_pls_golite062009
structure-specific DNA binding 0.707861773634749 bayes_pls_golite062009
0.596347353533061 bayes_pls_golite062009
single-stranded DNA binding 0.567929700499153 bayes_pls_golite062009
transferase activity 0.269890329731988 bayes_pls_golite062009
catalytic activity 0.254696427664799 bayes_pls_golite062009
protein binding 0.0494791880947549 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [111-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVTPPNLLDT TFKKKNKLYL KCASTFPPLN QLPFMNASAE QHYKEGLSIA RDSSKGKSDD  60
   61 ALTNLVYIGK NQIITLSNQN IPNTARVTVD TERKEVVSPI DAYKGKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.39794
Match: 1k3rA_
Description: Hypothetical protein MTH1 (MT0001), insert domain; Hypothetical protein MTH1 (MT0001), dimerisation domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle