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View Structure Prediction Details

Protein: GTR2
Organism: Saccharomyces cerevisiae
Length: 341 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GTR2.

Description E-value Query
Range		 Subject
Range
RRAGC_MOUSE - Ras-related GTP-binding protein C OS=Mus musculus GN=Rragc PE=1 SV=1
 2.0E-93 [8..325] [59..366]
ENSCJAT00000004312 - null
gi|123981662, gi... - gi|123996471|gb|ABM85837.1| Ras-related GTP binding C [synthetic construct], gi|123981662|gb|ABM8266...
RRAGC - Ras-related GTP binding C
 3.0E-93 [8..325] [60..367]
GTR2 - Putative GTP binding protein that negatively regulates Ran/Tc4 GTPase cycle; activates transcription...
gi|190406821 - gi|190406821|gb|EDV10088.1| GTP-binding protein GTR2 [Saccharomyces cerevisiae RM11-1a]
gi|207345042 - gi|207345042|gb|EDZ71989.1| YGR163Wp-like protein [Saccharomyces cerevisiae AWRI1631]
GTR2_YEAST - GTP-binding protein GTR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GTR2 PE=1 SV=1
gi|151943440 - gi|151943440|gb|EDN61751.1| GTP binding protein resemblance [Saccharomyces cerevisiae YJM789]
 4.0E-90 [1..341] [1..341]
GTR2_SCHPO - GTP-binding protein gtr2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gtr2 PE=3 SV=1
gtr2 - Gtr1 /RagA G protein Gtr2
 2.0E-78 [11..326] [5..311]
ragc-1 - status:Confirmed UniProt:Q9TVH6 protein_id:CAB60328.1
 5.0E-74 [3..325] [20..329]
ENSPTRT00000019157 - null
tr|G3I5Q9|G3I5Q9... - Ras-related protein Rab-11B OS=Cricetulus griseus GN=I79_018814 PE=3 SV=1
RB11B_RAT - Ras-related protein Rab-11B OS=Rattus norvegicus GN=Rab11b PE=1 SV=4
gi|90085246 - gi|90085246|dbj|BAE91364.1| unnamed protein product [Macaca fascicularis]
gi|226529709, gi... - gi|226529709|ref|NP_001142168.1| hypothetical protein LOC100274335 [Zea mays], gi|194707448|gb|ACF87...
gi|61355645 - gi|61355645|gb|AAX41161.1| RAB11B member RAS oncogene family [synthetic construct]
RB11B_BOVIN - Ras-related protein Rab-11B OS=Bos taurus GN=RAB11B PE=2 SV=3
CCDS12201.1_1 - null
gi|109123235 - gi|109123235|ref|XP_001093925.1| PREDICTED: RAB11B, member RAS oncogene family [Macaca mulatta]
RAB11B - RAB11B, member RAS oncogene family
 1.0E-68 [3..233] [5..217]
RB11D_LOTJA - Ras-related protein Rab11D OS=Lotus japonicus GN=RAB11D PE=2 SV=1
 2.0E-68 [3..232] [7..217]

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Predicted Domain #1
Region A:
Residues: [1-220] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLEATDSKA MVLLMGVRRC GKSSICKVVF HNMQPLDTLY LESTSNPSLE HFSTLIDLAV  60
   61 MELPGQLNYF EPSYDSERLF KSVGALVYVI DSQDEYINAI TNLAMIIEYA YKVNPSINIE 120
  121 VLIHKVDGLS EDFKVDAQRD IMQRTGEELL ELGLDGVQVS FYLTSIFDHS IYEAFSRIVQ 180
  181 KLIPELSFLE NMLDNLIQHS KIEKAFLFDV NSKIYVSTDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.69897
Match: 1g17A_
Description: Rab-related protein Sec4
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [221-341] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPVDIQMYEV CSEFIDVTID LFDLYKAPVL RNSQKSSDKD NVINPRNELQ NVSQLANGVI  60
   61 IYLRQMIRGL ALVAIIRPNG TDMESCLTVA DYNIDIFKKG LEDIWANARA SQAKNSIEDD 120
  121 V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.256 0.129 microautophagy c.23.1 CheY-like
View Download 0.416 0.072 microautophagy d.110.1 Profilin (actin-binding protein)
View Download 0.309 0.018 microautophagy d.52.7 Ribosome-binding factor A, RbfA
View Download 0.393 0.015 microautophagy d.82.2 Frataxin-like
View Download 0.416 0.013 cytoplasm d.110.1 Profilin (actin-binding protein)
View Download 0.256 0.010 GTPase activity c.23.1 CheY-like
View Download 0.309 0.001 GTPase activity d.52.7 Ribosome-binding factor A, RbfA
View Download 0.393 0.001 cytoplasm d.82.2 Frataxin-like
View Download 0.381 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.381 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.250 N/A N/A d.204.1 Ribosome binding protein Y (YfiA homologue)
View Download 0.240 N/A N/A d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
View Download 0.238 N/A N/A d.134.1 Sulfite reductase hemoprotein (SiRHP), domains 2 and 4
View Download 0.231 N/A N/A c.65.1 Formyltransferase
View Download 0.230 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.223 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.213 N/A N/A c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.213 N/A N/A b.55.1 PH domain-like
View Download 0.209 N/A N/A d.110.4 SNARE-like
View Download 0.202 N/A N/A d.222.1 YbaB-like

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle