| Protein: | MDR1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 950 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MDR1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..950] | [1..950] |
|
|
0.0 | [23..918] | [15..834] |
|
|
0.0 | [23..911] | [15..827] |
|
|
0.0 | [7..720] | [24..755] |
|
|
0.0 | [9..650] | [266..897] |
|
Region A: Residues: [1-164] |
1 11 21 31 41 51
| | | | | |
1 MSFFDSLRQK APFLDKLADS FTPTLTRDEK FRLKYKLPAN ENILEDTNAE VSFATSIKDG 60
61 KGHSDRVNNK GRKTAYVYSG RLFLTPHFLV FRDAFDHSSC VLILNISTIK RVERSPSESY 120
121 EFALLVTLYT GAKVLIQFIG IRYRSEQFCD KLKLNLKENI PNAK
|
| Detection Method: |  |
| Confidence: | 21.420216 |
| Match: | PF02893 |
| Description: | GRAM domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [165-369] |
1 11 21 31 41 51
| | | | | |
1 TLPAFLETSY SEFLIAKNIL GKKDITVPRA GLGQHFKYPG NPTMVKEKAK LRLWFDYFRE 60
61 NGRNLAVVQT PMFRKLIRIG VPNRMRGEIW ELCSGAMYMR YANSGEYERI LNENAGKTSQ 120
121 AIDEIEKDLK RSLPEYSAYQ TEEGIQRLRN VLTAYSWKNP DVGYCQAMNI VVAGFLIFMS 180
181 EEQAFWCLCN LCDIYVPGYY SKTMY
|
|
Region B: Residues: [423-453] |
1 11 21 31 41 51
| | | | | |
1 RIMDIFFMNG SITLFQVALA VLKINADDIL Q
|
| Detection Method: | |
| Confidence: | 43.154902 |
| Match: | 1fkmA_ |
| Description: | Ypt/Rab-GAP domain of gyp1p |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [370-422] |
1 11 21 31 41 51
| | | | | |
1 GTLLDQRVFE SFVEDRMPVL WEYILQHDIQ LSVVSLPWFL SLFFTSMPLE YAV
|
| Detection Method: | |
| Confidence: | 43.154902 |
| Match: | 1fkmA_ |
| Description: | Ypt/Rab-GAP domain of gyp1p |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.08545912858984 | bayes_pls_golite062009 |
| protein binding | 1.56086942180613 | bayes_pls_golite062009 |
| calcium ion binding | 1.33959449723205 | bayes_pls_golite062009 |
| cation binding | 1.09340191610586 | bayes_pls_golite062009 |
| metal ion binding | 1.09340191610586 | bayes_pls_golite062009 |
| ion binding | 1.08592956217627 | bayes_pls_golite062009 |
|
Region A: Residues: [454-522] |
1 11 21 31 41 51
| | | | | |
1 ADDDGMFIAI IKHYFQTLGQ SAHPDSSDIK YRQITKFQEL LVTAFKEFSV ISEEMAMHAR 60
61 HKYEKGIFQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [523-637] |
1 11 21 31 41 51
| | | | | |
1 NIETFMKRTQ LRHMPKTFNL SSDDLSNIYD MFYQSIETYK ISMGTGSSNM GFEVFIQFLS 60
61 KFCDSCRPCE KDKDPAFRKQ KRNFLQRLFD NWDSAHIGEL TLNDVVTGLD KLVTV
|
| Detection Method: | |
| Confidence: | 57.66807 |
| Match: | 1iku__ |
| Description: | Recoverin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [638-766] |
1 11 21 31 41 51
| | | | | |
1 DLLQAINYFF SLYDTDGDGE LHREEVLQLS EGLLLLTEPW KSGRYVDLLT KKRIEDDIAE 60
61 NIIKESGGEI ATMNQIELPT GVTIDEEKYK VEQAERYLKA ASNFLQRSFE YAKAVDLAEE 120
121 VNLIDLSDD
|
| Detection Method: | |
| Confidence: | 57.66807 |
| Match: | 1iku__ |
| Description: | Recoverin |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [767-950] |
1 11 21 31 41 51
| | | | | |
1 EGEEKRTVKQ KQLESIKANA ALDPTHPKVI DLPTFRMIIL ADETYELFFS NTLRSSVHVD 60
61 EHVNIDNKNK VLRSMFDGIL ADGKRVAEQV RRRVDSVATR SSIASVESTP TAAASSITTK 120
121 EEKYDDLDDF TSEHQPENEE LLQSSWFEID DANETSTKAI QERSFEPLSA NSSEEKSNLI 180
181 EFEA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
