| Protein: | TFC4 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1025 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TFC4.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..1025] | [1..1025] |
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0.0 | [28..1025] | [6..1028] |
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0.0 | [9..1023] | [16..1004] |
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2.0E-98 | [313..1024] | [88..814] |
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9.0E-88 | [230..1014] | [42..787] |
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1.0E-83 | [89..571] | [22..498] |
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1.0E-83 | [87..571] | [10..488] |
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2.0E-83 | [87..571] | [10..488] |
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4.0E-81 | [86..571] | [43..527] |
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9.0E-81 | [94..569] | [131..600] |
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Region A: Residues: [1-67] |
1 11 21 31 41 51
| | | | | |
1 MAAGKLKKEQ QNQSAERESA DTGKVNDEDE EHLYGNIDDY KHLIQDEEYD DEDVPHDLQL 60
61 SEDEYNS
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| Detection Method: |  |
| Confidence: | 34.0 |
| Match: | 1fchA_ |
| Description: | Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor) |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [68-403] |
1 11 21 31 41 51
| | | | | |
1 ERDSSLLAEF SDYGEISEDD EEDFMNAIRE ASNFKVKKKK KNDKGKSYGR QRKERVLDPE 60
61 VAQLLSQANE AFVRNDLQVA ERLFNEVIKK DARNFAAYET LGDIYQLQGR LNDCCNSWFL 120
121 AAHLNASDWE FWKIVAILSA DLDHVRQAIY CFSRVISLNP MEWESIYRRS MLYKKTGQLA 180
181 RALDGFQRLY MYNPYDANIL RELAILYVDY DRIEDSIELY MKVFNANVER REAILAALEN 240
241 ALDSSDEESA AEGEDADEKE PLEQDEDRQM FPDINWKKID AKYKCIPFDW SSLNILAELF 300
301 LKLAVSEVDG IKTIKKCARW IQRRESQTFW DHVPDD
|
| Detection Method: | |
| Confidence: | 4.69897 |
| Match: | 1b89A_ |
| Description: | Clathrin heavy chain proximal leg segment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [404-541] |
1 11 21 31 41 51
| | | | | |
1 SEFDNRRFKN STFDSLLAAE KEKSYNIPID IRVRLGLLRL NTDNLVEALN HFQCLYDETF 60
61 SDVADLYFEA ATALTRAEKY KEAIDFFTPL LSLEEWRTTD VFKPLARCYK EIESYETAKE 120
121 FYELAIKSEP DDLDIRVS
|
| Detection Method: | |
| Confidence: | 2.09691 |
| Match: | 1qqeA_ |
| Description: | Vesicular transport protein sec17 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 3.17166650775207 | bayes_pls_golite062009 |
| transcription regulator activity | 2.36976362065221 | bayes_pls_golite062009 |
| DNA binding | 1.72247907299633 | bayes_pls_golite062009 |
| protein binding | 1.72061787550863 | bayes_pls_golite062009 |
| nucleic acid binding | 1.63537681687141 | bayes_pls_golite062009 |
| transcription factor activity | 1.0205750374806 | bayes_pls_golite062009 |
| transcription factor binding | 0.447234745044969 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.201108481303385 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.0645101607447045 | bayes_pls_golite062009 |
| transcription activator activity | 0.0514451541233234 | bayes_pls_golite062009 |
|
Region A: Residues: [542-644] |
1 11 21 31 41 51
| | | | | |
1 LAEVYYRLND PETFKHMLVD VVEMRKHQVD ETLHRISNEK SSNDTSDISS KPLLEDSKFR 60
61 TFRKKKRTPY DAERERIERE RRITAKVVDK YEKMKKFELN SGL
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.527 | 0.108 | RNA polymerase III transcription factor activity | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.521 | 0.053 | RNA polymerase III transcription factor activity | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.679 | 0.040 | RNA polymerase III transcription factor activity | a.2.7 | tRNA-binding arm |
| View | Download | 0.644 | 0.019 | RNA polymerase III transcription factor activity | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.550 | 0.008 | RNA polymerase III transcription factor activity | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.492 | N/A | N/A | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
| View | Download | 0.440 | N/A | N/A | a.2.7 | tRNA-binding arm |
| View | Download | 0.427 | N/A | N/A | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.419 | N/A | N/A | a.2.5 | Prefoldin |
| View | Download | 0.411 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.378 | N/A | N/A | a.2.1 | GreA transcript cleavage protein, N-terminal domain |
| View | Download | 0.378 | N/A | N/A | d.80.1 | Tautomerase/MIF |
| View | Download | 0.376 | N/A | N/A | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.365 | N/A | N/A | f.17.2 | Cytochrome c oxidase subunit II-like, transmembrane region |
| View | Download | 0.332 | N/A | N/A | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.314 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.302 | N/A | N/A | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.300 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.299 | N/A | N/A | a.21.1 | HMG-box |
| View | Download | 0.288 | N/A | N/A | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.280 | N/A | N/A | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.274 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.274 | N/A | N/A | f.17.2 | Cytochrome c oxidase subunit II-like, transmembrane region |
| View | Download | 0.270 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.269 | N/A | N/A | d.110.4 | SNARE-like |
| View | Download | 0.256 | N/A | N/A | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.251 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.251 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.246 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.245 | N/A | N/A | d.58.16 | Poly(A) polymerase, C-terminal domain |
| View | Download | 0.245 | N/A | N/A | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.242 | N/A | N/A | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.241 | N/A | N/A | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.239 | N/A | N/A | d.58.21 | Molybdenum cofactor biosynthesis protein C, MoaC |
| View | Download | 0.232 | N/A | N/A | a.2.5 | Prefoldin |
| View | Download | 0.231 | N/A | N/A | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.227 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.221 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.213 | N/A | N/A | a.91.1 | Regulator of G-protein signalling, RGS |
| View | Download | 0.212 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.208 | N/A | N/A | g.44.1 | RING/U-box |
| View | Download | 0.204 | N/A | N/A | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.204 | N/A | N/A | a.156.1 | S13-like H2TH domain |
| View | Download | 0.201 | N/A | N/A | a.47.2 | t-snare proteins |
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Region A: Residues: [645-729] |
1 11 21 31 41 51
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1 NEAKQASIWI NTVSELVDIF SSVKNFFMKS RSRKFVGILR RTKKFNTELD FQIERLSKLA 60
61 EGDSVFEGPL MEERVTLTSA TELRG
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
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Region A: Residues: [730-824] |
1 11 21 31 41 51
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1 LSYEQWFELF MELSLVIAKY QSVEDGLSVV ETAQEVNVFF QDPERVKMMK FVKLAIVLQM 60
61 DDEEELAENL RGLLNQFQFN RKVLQVFMYS LCRGP
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| Detection Method: | |
| Confidence: | 13.05 |
| Match: | 1fchA |
| Description: | Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor) |
| Matching Structure (courtesy of the PDB): |
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Region A: Residues: [825-925] |
1 11 21 31 41 51
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1 SSLNILSSTI QQKFFLRQLK AFDSCRYNTE VNGQASITNK EVYNPNKKSS PYLYYIYAVL 60
61 LYSSRGFLSA LQYLTRLEED IPDDPMVNLL MGLSHIHRAM Q
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| Detection Method: | |
| Confidence: | 13.05 |
| Match: | 1fchA |
| Description: | Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor) |
| Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [926-1025] |
1 11 21 31 41 51
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1 RLTAQRHFQI FHGLRYLYRY HKIRKSLYTD LEKQEADYNL GRAFHLIGLV SIAIEYYNRV 60
61 LENYDDGKLK KHAAYNSIII YQQSGNVELA DHLMEKYLSI
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| Detection Method: | |
| Confidence: | 13.05 |
| Match: | 1fchA |
| Description: | Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor) |
| Matching Structure (courtesy of the PDB): |
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