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View Structure Prediction Details

Protein: ARO8
Organism: Saccharomyces cerevisiae
Length: 500 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARO8.

Description E-value Query
Range
Subject
Range
gi|7576444 - gi|7576444|dbj|BAA94600.1| 1-aminocyclopropane-1-carboxylate synthase [Populus euramericana]
gi|7576444 - dbj|BAA94600.1| 1-aminocyclopropane-1-carboxylate synthase [Populus euramericana]
0.0 [39..499] [14..436]
gi|3955254 - gi|3955254|gb|AAC83147.1| 1-aminocyclopropane-1-carboxylate synthase [Nicotiana glutinosa]
0.0 [39..497] [20..440]
gi|3668146, gi|1... - gi|6688886|emb|CAB65314.1| 1-aminocyclopropane-1-carboxylate synthase [Nicotiana tabacum], gi|366814...
0.0 [39..497] [20..440]
gi|4090535 - gi|4090535|gb|AAC98809.1| ACC synthase [Carica papaya]
0.0 [39..497] [17..438]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [39..497] [20..440]
gi|9719043 - gi|9719043|gb|AAF97615.1|U18057_1 1-amino-cyclopropane-1-carboxylate synthase [Lycopersicon esculent...
0.0 [39..497] [20..440]
1A1C_SOYBN - 1-aminocyclopropane-1-carboxylate synthase OS=Glycine max GN=ACS1 PE=2 SV=1
0.0 [37..498] [16..441]
gi|7209853 - gi|7209853|dbj|BAA92351.1| 1-aminocyclopropane-1-carboxylate synthase [Malus x domestica]
0.0 [41..497] [20..438]
gi|8570043 - gi|8570043|dbj|BAA96743.1| 1-aminocyclopropane-1-carboxylate synthase [Prunus persica]
0.0 [39..497] [19..438]

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Predicted Domain #1
Region A:
Residues: [1-22]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLPESKDFS YLFSDETNAR KP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [44-369]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPLKDYFPWD NLSVDSPKPP FPQGIGAPID EQNCIKYTVN KDYADKSANP SNDIPLSRAL  60
   61 QYGFSAGQPE LLNFIRDHTK IIHDLKYKDW DVLATAGNTN AWESTLRVFC NRGDVILVEA 120
  121 HSFSSSLASA EAQGVITFPV PIDADGIIPE KLAKVMENWT PGAPKPKLLY TIPTGQNPTG 180
  181 TSIADHRKEA IYKIAQKYDF LIVEDEPYYF LQMNPYIKDL KEREKAQSSP KQDHDEFLKS 240
  241 LANTFLSLDT EGRVIRMDSF SKVLAPGTRL GWITGSSKIL KPYLSLHEMT IQAPAGFTQV 300
  301 LVNATLSRWG QKGYLDWLLG LRHEYT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 140.29073
Match: 1bkgA_
Description: Aspartate aminotransferase, AAT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
4-aminobutyrate transaminase activity 2.50008459801306 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
transcription regulator activity 1.67701710033155 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 1.63055151623667 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 1.63055151623667 bayes_pls_golite062009
DNA binding 1.4774443071095 bayes_pls_golite062009
transferase activity 1.44093490824786 bayes_pls_golite062009
nucleic acid binding 1.39741122443159 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
kynureninase activity 1.27354164393136 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
transcription factor activity 1.15775909410582 bayes_pls_golite062009
binding 1.09053123792737 bayes_pls_golite062009
hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances 0.942545094747784 bayes_pls_golite062009
hydrolase activity, acting on acid carbon-carbon bonds 0.845816961387768 bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity 0.619695949258279 bayes_pls_golite062009
5-aminolevulinate synthase activity 0.54326874956263 bayes_pls_golite062009
structural molecule activity 0.347975812448725 bayes_pls_golite062009
pyridoxal phosphate binding 0.16957228630576 bayes_pls_golite062009
vitamin B6 binding 0.16957228630576 bayes_pls_golite062009
aromatic-amino-acid:2-oxoglutarate aminotransferase activity 0.0916183433120769 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [23-43]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPLKTCIHLF QDPNIIFLGG G

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [370-500]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKRDCAIDAL YKYLPQSDAF VINPPIAGMF FTVNIDASVH PEFKTKYNSD PYQLEQSLYH  60
   61 KVVERGVLVV PGSWFKSEGE TEPPQPAESK EVSNPNIIFF RGTYAAVSPE KLTEGLKRLG 120
  121 DTLYEEFGIS K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 140.29073
Match: 1bkgA_
Description: Aspartate aminotransferase, AAT
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle