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View Structure Prediction Details

Protein: MON1
Organism: Saccharomyces cerevisiae
Length: 644 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MON1.

Description E-value Query
Range
Subject
Range
MON1 - Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a co...
0.0 [1..644] [1..644]
gi|55620341, gi|... - gi|55620341|ref|XP_516471.1| PREDICTED: MON1 homolog A isoform 5 [Pan troglodytes], gi|114586959|ref...
MON1A - MON1 homolog A (yeast)
0.0 [175..644] [149..555]
gi|13874543 - gi|13874543|dbj|BAB46888.1| hypothetical protein [Macaca fascicularis]
0.0 [175..644] [171..577]
MON1A_MOUSE - Vacuolar fusion protein MON1 homolog A - Mus musculus (Mouse)
0.0 [175..644] [150..556]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [174..644] [113..520]
gi|26451129, gi|... - gi|62319772|dbj|BAD93763.1| hypothetical protein [Arabidopsis thaliana], gi|51970450|dbj|BAD43917.1|...
0.0 [174..644] [173..605]
CG11926-PA - This gene is referred to in FlyBase by the symbol Dmel\CG11926 (CG11926, FBgn0031640). It is a prote...
0.0 [177..644] [112..528]
aut12 - autophagy associated protein Aut12
MON1_SCHPO - Vacuolar fusion protein mon1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mon1 PE=3 SV=...
0.0 [179..644] [111..513]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLNESYLDA EIPKGQLKHS KSGNFEGIPI VATTSEPTTS VNLDETFFKK APIAMPICDD  60
   61 HSVSKSTSVN SLNTTSLASR RSPLQTKKLQ AKNNLLSADL AKSNDDTTRA LNC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transporter activity 1.65703073817987 bayes_pls_golite062009
transmembrane transporter activity 1.47755255763729 bayes_pls_golite062009
active transmembrane transporter activity 0.815884494512385 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [114-320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKKDFGPYLD SENDIRSRLA ESIYSMETSI RGSELQRRPY VSNEIPNVFK FSKFNSNCKL  60
   61 NESQTLCDKN FFIFTSAGKP IYCMHGKDEQ IMSYTGLVNT VISYFQVNGP SELKTISTLT 120
  121 SGKRLTFLDK SPILLMAQSE RGESSNELLN QLDFLYSYIL SSLSERQLLR LFSKRENFDL 180
  181 RNYLESTDFE NLDEICSLIC NRMFPDL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.04
Match: 1gw5S
Description: Sigma2 adaptin (clathrin coat assembly protein AP17)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [321-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLNSLQCLPF NHSSRLKLQN VVLQQLEKRQ DIPRGTLLYG LIIAPQNKLC CVLRPRGHTL  60
   61 HTTDLHLLFC LISHQFQNLD ETQELWVPIC FP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [413-644]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFNSSGFLYC YIKFLPNDTH SNEKSALVLI SAQKDAFFSL KSFSDELIIK LEEEKLLKKI  60
   61 NTSKGFKLSD IPAPMVHHFI YKSKQNVQYV MPHFEVNSNI ALDSSQGLEY ELKLKTYYQQ 120
  121 LHGTVVRDNG NLLSRSMLNF VRWSSKDNED LAMDETQMDF SELDEYIIGN SSFKQESVNM 180
  181 VGMAWVTPTF ELYLIGNNGI VDKRVLFKSA RKVANWCQKH ESRLFISDGA VF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle