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View Structure Prediction Details

Protein: MON1
Organism: Saccharomyces cerevisiae
Length: 644 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MON1.

Description E-value Query
Range
Subject
Range
MON1 - Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a co...
0.0 [1..644] [1..644]
gi|55620341, gi|... - gi|55620341|ref|XP_516471.1| PREDICTED: MON1 homolog A isoform 5 [Pan troglodytes], gi|114586959|ref...
MON1A - MON1 homolog A (yeast)
0.0 [175..644] [149..555]
gi|13874543 - gi|13874543|dbj|BAB46888.1| hypothetical protein [Macaca fascicularis]
0.0 [175..644] [171..577]
MON1A_MOUSE - Vacuolar fusion protein MON1 homolog A - Mus musculus (Mouse)
0.0 [175..644] [150..556]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [174..644] [113..520]
gi|26451129, gi|... - gi|62319772|dbj|BAD93763.1| hypothetical protein [Arabidopsis thaliana], gi|51970450|dbj|BAD43917.1|...
0.0 [174..644] [173..605]
CG11926-PA - This gene is referred to in FlyBase by the symbol Dmel\CG11926 (CG11926, FBgn0031640). It is a prote...
0.0 [177..644] [112..528]
aut12 - autophagy associated protein Aut12
MON1_SCHPO - Vacuolar fusion protein mon1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mon1 PE=3 SV=...
0.0 [179..644] [111..513]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLNESYLDA EIPKGQLKHS KSGNFEGIPI VATTSEPTTS VNLDETFFKK APIAMPICDD  60
   61 HSVSKSTSVN SLNTTSLASR RSPLQTKKLQ AKNNLLSADL AKSNDDTTRA LNC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transporter activity 1.65703073817987 bayes_pls_golite062009
transmembrane transporter activity 1.47755255763729 bayes_pls_golite062009
active transmembrane transporter activity 0.815884494512385 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [114-320]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKKDFGPYLD SENDIRSRLA ESIYSMETSI RGSELQRRPY VSNEIPNVFK FSKFNSNCKL  60
   61 NESQTLCDKN FFIFTSAGKP IYCMHGKDEQ IMSYTGLVNT VISYFQVNGP SELKTISTLT 120
  121 SGKRLTFLDK SPILLMAQSE RGESSNELLN QLDFLYSYIL SSLSERQLLR LFSKRENFDL 180
  181 RNYLESTDFE NLDEICSLIC NRMFPDL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.04
Match: 1gw5S
Description: Sigma2 adaptin (clathrin coat assembly protein AP17)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [321-412]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLNSLQCLPF NHSSRLKLQN VVLQQLEKRQ DIPRGTLLYG LIIAPQNKLC CVLRPRGHTL  60
   61 HTTDLHLLFC LISHQFQNLD ETQELWVPIC FP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.547 a.3.1 Cytochrome c
View Download 0.540 d.129.1 TATA-box binding protein-like
View Download 0.608 d.130.1 S-adenosylmethionine synthetase
View Download 0.613 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.558 d.58.27 Translational regulator protein regA
View Download 0.532 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.486 b.1.2 Fibronectin type III
View Download 0.476 a.74.1 Cyclin-like
View Download 0.475 a.74.1 Cyclin-like
View Download 0.472 a.74.1 Cyclin-like
View Download 0.471 d.58.49 YajQ-like
View Download 0.470 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.467 d.57.1 DNA damage-inducible protein DinI
View Download 0.464 d.58.49 YajQ-like
View Download 0.460 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.458 d.58.49 YajQ-like
View Download 0.454 a.74.1 Cyclin-like
View Download 0.453 a.74.1 Cyclin-like
View Download 0.448 d.237.1 Hypothetical protein YjiA, C-terminal domain
View Download 0.440 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.434 d.93.1 SH2 domain
View Download 0.429 d.58.17 Metal-binding domain
View Download 0.426 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.421 d.58.12 eEF-1beta-like
View Download 0.421 d.88.1 SRF-like
View Download 0.414 a.74.1 Cyclin-like
View Download 0.409 a.142.1 PTS-regulatory domain, PRD
View Download 0.391 d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
View Download 0.390 b.1.13 Superoxide reductase-like
View Download 0.388 d.80.1 Tautomerase/MIF
View Download 0.384 d.58.7 RNA-binding domain, RBD
View Download 0.372 d.130.1 S-adenosylmethionine synthetase
View Download 0.370 a.74.1 Cyclin-like
View Download 0.370 d.58.4 Dimeric alpha+beta barrel
View Download 0.369 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.367 d.17.1 Cystatin/monellin
View Download 0.364 d.58.7 RNA-binding domain, RBD
View Download 0.356 a.74.1 Cyclin-like
View Download 0.344 d.52.4 YhbC-like, N-terminal domain
View Download 0.340 d.58.7 RNA-binding domain, RBD
View Download 0.338 d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.335 a.24.3 Cytochromes
View Download 0.335 a.59.1 PAH2 domain
View Download 0.333 d.58.27 Translational regulator protein regA
View Download 0.328 d.21.1 Diaminopimelate epimerase-like
View Download 0.328 c.30.1 PreATP-grasp domain
View Download 0.327 d.52.4 YhbC-like, N-terminal domain
View Download 0.325 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.322 d.53.1 Ribosomal protein S3 C-terminal domain
View Download 0.319 d.141.1 Ribosomal protein L6
View Download 0.317 d.130.1 S-adenosylmethionine synthetase
View Download 0.313 d.58.7 RNA-binding domain, RBD
View Download 0.313 d.57.1 DNA damage-inducible protein DinI
View Download 0.312 a.64.1 Saposin
View Download 0.306 d.67.2 Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
View Download 0.305 d.58.42 N-utilization substance G protein NusG, N-terminal domain
View Download 0.302 d.110.2 GAF domain-like
View Download 0.301 d.57.1 DNA damage-inducible protein DinI
View Download 0.300 a.60.1 SAM/Pointed domain
View Download 0.300 d.109.1 Actin depolymerizing proteins
View Download 0.299 d.58.4 Dimeric alpha+beta barrel
View Download 0.299 a.60.13 Putative methyltransferase TM0872, insert domain
View Download 0.295 d.130.1 S-adenosylmethionine synthetase
View Download 0.293 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.287 d.130.1 S-adenosylmethionine synthetase
View Download 0.284 d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.281 c.78.2 Aspartate/glutamate racemase
View Download 0.281 d.57.1 DNA damage-inducible protein DinI
View Download 0.276 f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.270 a.118.8 TPR-like
View Download 0.262 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.260 d.15.6 Superantigen toxins, C-terminal domain
View Download 0.260 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.260 d.204.1 Ribosome binding protein Y (YfiA homologue)
View Download 0.259 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.257 d.15.6 Superantigen toxins, C-terminal domain
View Download 0.255 d.197.1 Protein-L-isoaspartyl O-methyltransferase, C-terminal domain
View Download 0.253 d.57.1 DNA damage-inducible protein DinI
View Download 0.252 a.26.1 4-helical cytokines
View Download 0.252 a.7.5 Tubulin chaperone cofactor A
View Download 0.250 b.40.4 Nucleic acid-binding proteins
View Download 0.244 c.47.1 Thioredoxin-like
View Download 0.241 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.241 b.61.3 D-aminopeptidase, middle and C-terminal domains
View Download 0.239 d.15.6 Superantigen toxins, C-terminal domain
View Download 0.239 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.238 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.236 d.58.7 RNA-binding domain, RBD
View Download 0.228 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.224 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.222 a.2.3 Chaperone J-domain
View Download 0.221 d.57.1 DNA damage-inducible protein DinI
View Download 0.221 a.109.1 Class II MHC-associated invariant chain ectoplasmic trimerization domain
View Download 0.220 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.219 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.217 a.71.2 Helical domain of Sec23/24
View Download 0.210 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.210 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.208 d.80.1 Tautomerase/MIF
View Download 0.206 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.202 a.74.1 Cyclin-like
View Download 0.200 d.15.6 Superantigen toxins, C-terminal domain

Predicted Domain #4
Region A:
Residues: [413-644]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFNSSGFLYC YIKFLPNDTH SNEKSALVLI SAQKDAFFSL KSFSDELIIK LEEEKLLKKI  60
   61 NTSKGFKLSD IPAPMVHHFI YKSKQNVQYV MPHFEVNSNI ALDSSQGLEY ELKLKTYYQQ 120
  121 LHGTVVRDNG NLLSRSMLNF VRWSSKDNED LAMDETQMDF SELDEYIIGN SSFKQESVNM 180
  181 VGMAWVTPTF ELYLIGNNGI VDKRVLFKSA RKVANWCQKH ESRLFISDGA VF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle