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View Structure Prediction Details

Protein: SEH1
Organism: Saccharomyces cerevisiae
Length: 349 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEH1.

Description E-value Query
Range
Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
5.0E-97 [4..345] [1153..1451]
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
1.0E-96 [4..347] [878..1178]

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Predicted Domain #1
Region A:
Residues: [1-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQPFDSGHDD LVHDVVYDFY GRHVATCSSD QHIKVFKLDK DTSNWELSDS WRAHDSSIVA  60
   61 IDWASPEYGR IIASASYDKT VKLWEEDPDQ EECSGRRWNK LCTLNDSKGS LYSVKFAPAH 120
  121 LGLKLACLGN DGILRLYDAL EPSDLRSWTL TSEMKVLSIP PANHLQSDFC LSWCPSRFSP 180
  181 EKLAVSALEQ AIIYQRGKDG KLHVAAKLPG HKSLIRSISW APSIGRWYQL IATGCKDGRI 240
  241 RIFKITEKLS PLASEESLTN SNMFDNSADV DMDAQGRSDS NTEEKAELQS NLQVELLSEH 300
  301 DDHNGEVWSV SWNLTGTILS SAGDDGKVRL WKATYSNEFK CMSVITAQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 95.612477
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.2778252170547 bayes_pls_golite062009
snoRNA binding 1.61553185503007 bayes_pls_golite062009
protein binding 1.24173112731149 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
protein transporter activity 0.964340340346761 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
nucleic acid binding 0.693814013902061 bayes_pls_golite062009
cytoskeletal protein binding 0.359536347486199 bayes_pls_golite062009
receptor activity 0.314900439093911 bayes_pls_golite062009
transcription regulator activity 0.190100099674138 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.168317261786777 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.132660456600365 bayes_pls_golite062009
kinase activity 0.127621956173205 bayes_pls_golite062009
0.0248988265652406 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle