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View Structure Prediction Details

Protein: SWI4
Organism: Saccharomyces cerevisiae
Length: 1093 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SWI4.

Description E-value Query
Range
Subject
Range
SWI4 - DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert ...
SWI4_YEAST - Regulatory protein SWI4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SWI4 PE=1 SV=2
0.0 [1..1093] [1..1093]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [1..1093] [1..1093]
gi|1845265 - gi|1845265|gb|AAB47805.1| ankyrin [Homo sapiens]
0.0 [291..857] [70..655]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [291..857] [103..688]

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Predicted Domain #1
Region A:
Residues: [1-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPFDVLISNQ KDNTNHQNIT PISKSVLLAP HSNHPVIEIA TYSETDVYEC YIRGFETKIV  60
   61 MRRTKDDWIN ITQVFKIAQF SKTKRTKILE KESNDMQHEK VQGGYGRFQG TWIPLDSAKF 120
  121 LVNKYEIIDP VVNSILTFQF DPNNPPPKRS KNSILRKTSP GTKIT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 259.38764
Match: 1mb1__
Description: DNA-binding domain of Mlu1-box binding protein MBP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.36949648004482 bayes_pls_golite062009
DNA binding 4.06494205639151 bayes_pls_golite062009
nucleic acid binding 3.98559547948274 bayes_pls_golite062009
transcription factor activity 3.87642218322379 bayes_pls_golite062009
sequence-specific DNA binding 3.19892138828988 bayes_pls_golite062009
binding 2.79149251200147 bayes_pls_golite062009
protein binding 1.55473080522232 bayes_pls_golite062009
transcription repressor activity 0.838109968340069 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [166-420]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPSSYNKTPR KKNSSSSTSA TTTAANKKGK KNASINQPNP SPLQNLVFQT PQQFQVNSSM  60
   61 NIMNNNDNHT TMNFNNDTRH NLINNISNNS NQSTIIQQQK SIHENSFNNN YSATQKPLQF 120
  121 FPIPTNLQNK NVALNNPNNN DSNSYSHNID NVINSSNNNN NGNNNNLIIV PDGPMQSQQQ 180
  181 QQHHHEYLTN NFNHSMMDSI TNGNSKKRRK KLNQSNEQQF YNQQEKIQRH FKLMKQPLLW 240
  241 QSFQNPNDHH NEYCD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [421-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNGSNNNNNT VASNGSSIEV FSSNENDNSM NMSSRSMTPF SAGNTSSQNK LENKMTDQEY  60
   61 KQTILTILSS ERSSDVDQAL LATLYPAPKN 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.154902
Match: 1awcB_
Description: GA bindinig protein (GABP) beta 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.69918165732603 bayes_pls_golite062009
binding 2.60916417202222 bayes_pls_golite062009
transcription regulator activity 2.37103377984038 bayes_pls_golite062009
nucleic acid binding 1.8957142857582 bayes_pls_golite062009
DNA binding 1.78305438715057 bayes_pls_golite062009
transcription activator activity 1.6418915400902 bayes_pls_golite062009
transcription factor activity 1.2667825651547 bayes_pls_golite062009
transcription factor binding 1.06366405671195 bayes_pls_golite062009
sequence-specific DNA binding 0.949906091645366 bayes_pls_golite062009
structural molecule activity 0.648591660171134 bayes_pls_golite062009
cytoskeletal protein binding 0.63796241781934 bayes_pls_golite062009
structural constituent of cytoskeleton 0.32425530306039 bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity 0.0462605323512499 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [511-690]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FNINFEIDDQ GHTPLHWATA MANIPLIKML ITLNANALQC NKLGFNCITK SIFYNNCYKE  60
   61 NAFDEIISIL KICLITPDVN GRLPFHYLIE LSVNKSKNPM IIKSYMDSII LSLGQQDYNL 120
  121 LKICLNYQDN IGNTPLHLSA LNLNFEVYNR LVYLGASTDI LNLDNESPAS IMNKFNTPAG 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 127.457575
Match: 1sw6A_
Description: Swi6 ankyrin-repeat fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [691-1093]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSNSRNNNTK ADRKLARNLP QKNYYQQQQQ QQQPQNNVKI PKIIKTQHPD KEDSTADVNI  60
   61 AKTDSEVNES QYLHSNQPNS TNMNTIMEDL SNINSFVTSS VIKDIKSTPS KILENSPILY 120
  121 RRRSQSISDE KEKAKDNENQ VEKKKDPLNS VKTAMPSLES PSSLLPIQMS PLGKYSKPLS 180
  181 QQINKLNTKV SSLQRIMGEE IKNLDNEVVE TESSISNNKK RLITIAHQIE DAFDSVSNKT 240
  241 PINSISDLQS RIKETSSKLN SEKQNFIQSL EKSQALKLAT IVQDEESKVD MNTNSSSHPE 300
  301 KQEDEEPIPK STSETSSPKN TKADAKFSNT VQESYDVNET LRLATELTIL QFKRRMTTLK 360
  361 ISEAKSKINS SVKLDKYRNL IGITIENIDS KLDDIEKDLR ANA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle