| Protein: | PTP3 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 928 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTP3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..928] | [1..928] |
|
|
0.0 | [117..785] | [27..700] |
|
|
0.0 | [117..785] | [27..700] |
|
|
0.0 | [239..779] | [648..1152] |
|
|
0.0 | [291..792] | [20..501] |
|
|
0.0 | [291..792] | [20..501] |
|
|
0.0 | [291..792] | [20..504] |
|
Region A: Residues: [1-80] |
1 11 21 31 41 51
| | | | | |
1 MKDSVDCPSI LPTDRTSVLS ETSTLVGSSS HVYSRHAPMN SYHNSMNSNI YHSPKASSPL 60
61 VSYKTSSPVL LKRATAPVLP
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [81-248] |
1 11 21 31 41 51
| | | | | |
1 SFKPKEQRYN KPQGCSLITA VELGKIIETL PDEKVLLLDV RPFTEHAKSI ITNSIHVCLP 60
61 STLLRRKNFT FSKLLDNLTP SEQSVLKSKL AIDNLRIIIY DSTANQTESS VSLPCYGIAS 120
121 KLIEFDTNVK KTVSILMCGF PQFKILFPDH INTNTFNSDC ISSAEPKS
|
| Detection Method: | |
| Confidence: | 7.221849 |
| Match: | 1hzmA_ |
| Description: | Erk2 binding domain of Mapk phosphatase mkp-3 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphoprotein phosphatase activity | 4.79074052803751 | bayes_pls_golite062009 |
| phosphatase activity | 4.08369475076737 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 3.88616276399434 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 3.24681684836294 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activity | 2.84204105189999 | bayes_pls_golite062009 |
| hydrolase activity | 2.12055507229256 | bayes_pls_golite062009 |
| binding | 1.72957395505299 | bayes_pls_golite062009 |
| catalytic activity | 0.687308230067573 | bayes_pls_golite062009 |
| thiosulfate sulfurtransferase activity | 0.621422565731405 | bayes_pls_golite062009 |
| protein binding | 0.515609053278812 | bayes_pls_golite062009 |
| transferase activity | 0.302497611306574 | bayes_pls_golite062009 |
|
Region A: Residues: [249-491] |
1 11 21 31 41 51
| | | | | |
1 PKTNLMNSLH NTAPHMTATT PLSSPQMNLK LKVPDDSRSD HSNFSSSPSP RNVLSDSPMS 60
61 SSSPISALFK FQLPAPQTNI NQMFKFSQNE EIMGLETYLS AVNIKEEHER WYNNDSAKKS 120
121 LQNFQFPKNQ NSLEKDTNKD KLGFQIRYEN LSKNYEKEVI DSVIPEWFQH LMSIPKIELV 180
181 SQFQKLDFLE KRRLNHSVSF RKKENSFILE KPSSYPEQLT STSSSTIMPP KFPDVNKVQK 240
241 RSH
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [492-793] |
1 11 21 31 41 51
| | | | | |
1 SQPIFTQYSK YKSMLSLESD SDSESDDVII SSGVELGAKN RYKDIFPYEH SRVILKKGLQ 60
61 SSKGIKHSHS TSDGGILDNY INANYLSLPR FSVEQNSSFQ TTTTTTRRVR YIATQAPMPS 120
121 TVHDFYTCIL NNGVPLVLSL TNDFENGIEK CYRYWQEGNY NGIHVKLLEK KILKMPSTTS 180
181 MRKNTMGTQN SSLYSAGVQG NSSNYSTDND NDNDNNNNNN NNSNIPVTAA ACDDDDDDDD 240
241 DAILIRQILL TYHDQEKPYE LLQIQVKNWP DLGTLLNPIS ILQAINVKNH IIDTLFARNY 300
301 YQ
|
| Detection Method: | |
| Confidence: | 241.9691 |
| Match: | 1gwz__ |
| Description: | Tyrosine phosphatase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [794-928] |
1 11 21 31 41 51
| | | | | |
1 NDQLPTILVH CSAGCGRTGT LCTIDSILSN FEMFEMLQKE FVKLKYPAKL FDPISWTINI 60
61 FRKERISMVQ NINQFIFIYD CLLFYFRLRL DDITERTDGD GSNKDNISLS ALIEQIEKLE 120
121 ILQTFVDDKL KELPQ
|
| Detection Method: | |
| Confidence: | 14.89 |
| Match: | 1bzcA |
| Description: | Tyrosine phosphatase |
Matching Structure (courtesy of the PDB): |
|
