| Protein: | PTP3 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 928 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTP3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..928] | [1..928] |
|
|
0.0 | [117..785] | [27..700] |
|
|
0.0 | [117..785] | [27..700] |
|
|
0.0 | [239..779] | [648..1152] |
|
|
0.0 | [291..792] | [20..501] |
|
|
0.0 | [291..792] | [20..501] |
|
|
0.0 | [291..792] | [20..504] |
|
Region A: Residues: [1-80] |
1 11 21 31 41 51
| | | | | |
1 MKDSVDCPSI LPTDRTSVLS ETSTLVGSSS HVYSRHAPMN SYHNSMNSNI YHSPKASSPL 60
61 VSYKTSSPVL LKRATAPVLP
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.760 | c.47.1 | Thioredoxin-like |
| View | Download | 0.526 | a.77.1 | DEATH domain |
| View | Download | 0.496 | b.48.1 | mu transposase, C-terminal domain |
| View | Download | 0.760 | c.47.1 | Thioredoxin-like |
| View | Download | 0.526 | a.77.1 | DEATH domain |
| View | Download | 0.496 | b.48.1 | mu transposase, C-terminal domain |
| View | Download | 0.459 | c.47.1 | Thioredoxin-like |
| View | Download | 0.451 | c.47.1 | Thioredoxin-like |
| View | Download | 0.413 | a.70.1 | N-terminal domain of the delta subunit of the F1F0-ATP synthase |
| View | Download | 0.406 | c.47.1 | Thioredoxin-like |
| View | Download | 0.390 | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.374 | d.26.3 | Chitinase insertion domain |
| View | Download | 0.360 | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.359 | d.169.1 | C-type lectin-like |
| View | Download | 0.351 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.349 | d.74.2 | C-terminal domain of arginine repressor |
| View | Download | 0.316 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.310 | b.34.1 | C-terminal domain of transcriptional repressors |
| View | Download | 0.304 | d.68.1 | Translation initiation factor IF3, C-terminal domain |
| View | Download | 0.300 | b.38.1 | Sm-like ribonucleoproteins |
| View | Download | 0.290 | d.39.1 | Dynein light chain 8 (DLC8) |
| View | Download | 0.286 | b.34.11 | GW domain |
| View | Download | 0.277 | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.264 | d.1.1 | Microbial ribonucleases |
| View | Download | 0.257 | a.77.1 | DEATH domain |
| View | Download | 0.250 | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.247 | d.198.2 | Arp2/3 complex subunits |
| View | Download | 0.246 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.243 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.240 | b.34.2 | SH3-domain |
| View | Download | 0.239 | b.55.1 | PH domain-like |
| View | Download | 0.238 | d.24.1 | Pili subunits |
| View | Download | 0.229 | a.4.1 | Homeodomain-like |
| View | Download | 0.225 | c.15.1 | BRCT domain |
| View | Download | 0.217 | b.101.1 | Ribonuclease domain of colicin E3 |
| View | Download | 0.216 | a.39.1 | EF-hand |
|
Region A: Residues: [81-248] |
1 11 21 31 41 51
| | | | | |
1 SFKPKEQRYN KPQGCSLITA VELGKIIETL PDEKVLLLDV RPFTEHAKSI ITNSIHVCLP 60
61 STLLRRKNFT FSKLLDNLTP SEQSVLKSKL AIDNLRIIIY DSTANQTESS VSLPCYGIAS 120
121 KLIEFDTNVK KTVSILMCGF PQFKILFPDH INTNTFNSDC ISSAEPKS
|
| Detection Method: | |
| Confidence: | 7.221849 |
| Match: | 1hzmA_ |
| Description: | Erk2 binding domain of Mapk phosphatase mkp-3 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphoprotein phosphatase activity | 4.79074052803751 | bayes_pls_golite062009 |
| phosphatase activity | 4.08369475076737 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 3.88616276399434 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 3.24681684836294 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activity | 2.84204105189999 | bayes_pls_golite062009 |
| hydrolase activity | 2.12055507229256 | bayes_pls_golite062009 |
| binding | 1.72957395505299 | bayes_pls_golite062009 |
| catalytic activity | 0.687308230067573 | bayes_pls_golite062009 |
| thiosulfate sulfurtransferase activity | 0.621422565731405 | bayes_pls_golite062009 |
| protein binding | 0.515609053278812 | bayes_pls_golite062009 |
| transferase activity | 0.302497611306574 | bayes_pls_golite062009 |
|
Region A: Residues: [249-491] |
1 11 21 31 41 51
| | | | | |
1 PKTNLMNSLH NTAPHMTATT PLSSPQMNLK LKVPDDSRSD HSNFSSSPSP RNVLSDSPMS 60
61 SSSPISALFK FQLPAPQTNI NQMFKFSQNE EIMGLETYLS AVNIKEEHER WYNNDSAKKS 120
121 LQNFQFPKNQ NSLEKDTNKD KLGFQIRYEN LSKNYEKEVI DSVIPEWFQH LMSIPKIELV 180
181 SQFQKLDFLE KRRLNHSVSF RKKENSFILE KPSSYPEQLT STSSSTIMPP KFPDVNKVQK 240
241 RSH
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [492-793] |
1 11 21 31 41 51
| | | | | |
1 SQPIFTQYSK YKSMLSLESD SDSESDDVII SSGVELGAKN RYKDIFPYEH SRVILKKGLQ 60
61 SSKGIKHSHS TSDGGILDNY INANYLSLPR FSVEQNSSFQ TTTTTTRRVR YIATQAPMPS 120
121 TVHDFYTCIL NNGVPLVLSL TNDFENGIEK CYRYWQEGNY NGIHVKLLEK KILKMPSTTS 180
181 MRKNTMGTQN SSLYSAGVQG NSSNYSTDND NDNDNNNNNN NNSNIPVTAA ACDDDDDDDD 240
241 DAILIRQILL TYHDQEKPYE LLQIQVKNWP DLGTLLNPIS ILQAINVKNH IIDTLFARNY 300
301 YQ
|
| Detection Method: | |
| Confidence: | 241.9691 |
| Match: | 1gwz__ |
| Description: | Tyrosine phosphatase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [794-928] |
1 11 21 31 41 51
| | | | | |
1 NDQLPTILVH CSAGCGRTGT LCTIDSILSN FEMFEMLQKE FVKLKYPAKL FDPISWTINI 60
61 FRKERISMVQ NINQFIFIYD CLLFYFRLRL DDITERTDGD GSNKDNISLS ALIEQIEKLE 120
121 ILQTFVDDKL KELPQ
|
| Detection Method: | |
| Confidence: | 14.89 |
| Match: | 1bzcA |
| Description: | Tyrosine phosphatase |
Matching Structure (courtesy of the PDB): |
|
