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View Structure Prediction Details

Protein: GDA1
Organism: Saccharomyces cerevisiae
Length: 518 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GDA1.

Description E-value Query
Range
Subject
Range
gi|190405523 - gi|190405523|gb|EDV08790.1| guanosine diphosphatase of Golgi membrane [Saccharomyces cerevisiae RM11...
GDA1_YEAST - Guanosine-diphosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GDA1 PE=1 SV=1
gi|207346101 - gi|207346101|gb|EDZ72701.1| YEL042Wp-like protein [Saccharomyces cerevisiae AWRI1631]
GDA1 - Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golg...
gi|151944669 - gi|151944669|gb|EDN62928.1| guanosine diphosphatase [Saccharomyces cerevisiae YJM789]
0.0 [1..518] [1..518]
GDA1_KLULA - Guanosine-diphosphatase OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267...
GDA1_KLULA - Guanosine-diphosphatase OS=Kluyveromyces lactis GN=GDA1 PE=3 SV=1
0.0 [4..515] [6..518]
GDA1_CANAL - Guanosine-diphosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GDA1 PE=3 SV=1
GDA1_CANAL - Guanosine-diphosphatase OS=Candida albicans GN=GDA1 PE=3 SV=1
gi|238881009 - gi|238881009|gb|EEQ44647.1| guanosine-diphosphatase [Candida albicans WO-1]
0.0 [58..515] [130..595]
gi|28923035, gi|... - gi|32404804|ref|XP_323015.1| hypothetical protein ( (AL513467) probable guanosine-diphosphatase [Neu...
gi|85103299 - gi|85103299|ref|XP_961489.1| guanosine-diphosphatase [Neurospora crassa OR74A]
0.0 [60..516] [89..553]
GDA1_ASPFU - (Q8TGG8) Probable guanosine-diphosphatase (EC 3.6.1.42) (GDPase)
0.0 [71..516] [90..555]
GDA1_SCHPO - Guanosine-diphosphatase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gdp1 PE=3 SV=1
gda1 - guanosine-diphosphatase Gda1
0.0 [60..516] [103..553]
gi|55664712, gi|... - gi|55958874|emb|CAI16771.1| ectonucleoside triphosphate diphosphohydrolase 1 [Homo sapiens], gi|5566...
0.0 [78..505] [41..465]
ENTP1_RAT - Ectonucleoside triphosphate diphosphohydrolase 1 OS=Rattus norvegicus GN=Entpd1 PE=1 SV=1
0.0 [78..505] [34..459]
gi|13905252 - gi|13905252|gb|AAH06924.1| Entpd4 protein [Mus musculus]
0.0 [52..503] [46..520]

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Predicted Domain #1
Region A:
Residues: [1-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPIFRNYRF AIGAFAVIML ILLIKTSSIG PPSIARTVTP NASIPKTPED ISILPVNDEP  60
   61 GYLQDSKTEQ NYPELADAVK SQTSQTCSEE HKYVIMIDAG STGSRVHIYK FDVCTSPPTL 120
  121 LDEKFDMLEP GLSSFDTDSV GAANSLDPLL KVAMNYVPIK ARSCTPVAVK ATAGLRLLGD 180
  181 AKSSKILSAV RDHLEKDYPF PVVEGDGVSI MGGDEEGVFA WITTNYLLGN IGANGPKLPT 240
  241 AAVFDLGGGS TQIVFEPTFP INEKMVDGEH KFDLKFG

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.08
Match: 1bg3A
Description: Mammalian type I hexokinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
substrate-specific transporter activity 2.6067350860805 bayes_pls_golite062009
binding 1.67810028738512 bayes_pls_golite062009
kinase activity 1.49017495306118 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.41202247176912 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.17094423081025 bayes_pls_golite062009
carbohydrate kinase activity 0.918413613159579 bayes_pls_golite062009
protein binding 0.909114722614987 bayes_pls_golite062009
peptide binding 0.512219022453579 bayes_pls_golite062009
hexokinase activity 0.3464071310254 bayes_pls_golite062009
catalytic activity 0.308539563780047 bayes_pls_golite062009
protein kinase activity 0.273427627634136 bayes_pls_golite062009
nucleic acid binding 0.157726298952452 bayes_pls_golite062009
glucokinase activity 0.0827631486617343 bayes_pls_golite062009
transcription regulator activity 0.0562867443774764 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.0272188887044016 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [278-518]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DENYTLYQFS HLGYGLKEGR NKVNSVLVEN ALKDGKILKG DNTKTHQLSS PCLPPKVNAT  60
   61 NEKVTLESKE TYTIDFIGPD EPSGAQCRFL TDEILNKDAQ CQSPPCSFNG VHQPSLVRTF 120
  121 KESNDIYIFS YFYDRTRPLG MPLSFTLNEL NDLARIVCKG EETWNSVFSG IAGSLDELES 180
  181 DSHFCLDLSF QVSLLHTGYD IPLQRELRTG KKIANKEIGW CLGASLPLLK ADNWKCKIQS 240
  241 A

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [439-518]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETWNSVFSGI AGSLDELESD SHFCLDLSFQ VSLLHTGYDI PLQRELRTGK KIANKEIGWC  60
   61 LGASLPLLKA DNWKCKIQSA 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle