| Protein: | GEA2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1459 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GEA2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [7..1413] | [10..1407] |
|
|
0.0 | [12..1405] | [32..1380] |
|
|
0.0 | [12..1405] | [32..1380] |
|
|
0.0 | [211..1386] | [300..1474] |
|
Region A: Residues: [1-545] |
1 11 21 31 41 51
| | | | | |
1 MSDREFVTVD PVTIIIKECI NLSTAMRKYS KFTSQSGVAA LLGGGSEIFS NQDDYLAHTF 60
61 NNLNTNKHND PFLSGFIQLR LMLNKLKNLD NIDSLTILQP FLLIVSTSSI SGYITSLALD 120
121 SLQKFFTLNI INESSQNYIG AHRATVNALT HCRFEGSQQL SDDSVLLKVV FLLRSIVDSP 180
181 YGDLLSNSII YDVLQTILSL ACNNRRSEVL RNAAQSTMIA VTVKIFSKLK TIEPVNVNQI 240
241 YINDESYTND VLKADTIGTN VESKEEGSQE DPIGMKVNNE EAISEDDGIE EEHIHSEKST 300
301 NGAEQLDIVQ KTTRSNSRIQ AYADDNYGLP VVRQYLNLLL SLIAPENELK HSYSTRIFGL 360
361 ELIQTALEIS GDRLQLYPRL FTLISDPIFK SILFIIQNTT KLSLLQATLQ LFTTLVVILG 420
421 NNLQLQIELT LTRIFSILLD DGTANNSSSE NKNKPSIIKE LLIEQISILW TRSPSFFTST 480
481 FINFDCNLDR ADVSINFLKA LTKLALPESA LTTTESVPPI CLEGLVSLVD DMFDHMKDID 540
541 REEFG
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [546-626] |
1 11 21 31 41 51
| | | | | |
1 RQKNEMEILK KRDRKTEFIE CTNAFNEKPK KGIPMLIEKG FIASDSDKDI AEFLFNNNNR 60
61 MNKKTIGLLL CHPDKVSLLN E
|
| Detection Method: | |
| Confidence: | 1294.154902 |
| Match: | 1ku1A_ |
| Description: | ARF guanine-exchange factor 2, Gea2 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [627-792] |
1 11 21 31 41 51
| | | | | |
1 YIRLFDFSGL RVDEAIRILL TKFRLPGESQ QIERIIEAFS SAYCENQDYD PSKISDNAED 60
61 DISTVQPDAD SVFILSYSII MLNTDLHNPQ VKEHMSFEDY SGNLKGCCNH KDFPFWYLDR 120
121 IYCSIRDKEI VMPEEHHGNE KWFEDAWNNL ISSTTVITEI KKDTQS
|
| Detection Method: | |
| Confidence: | 1294.154902 |
| Match: | 1ku1A_ |
| Description: | ARF guanine-exchange factor 2, Gea2 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [793-1114] |
1 11 21 31 41 51
| | | | | |
1 VMDKLTPLEL LNFDRAIFKQ VGPSIVSTLF NIYVVASDDH ISTRMITSLD KCSYISAFFD 60
61 FKDLFNDILN SIAKGTTLIN SSHDDELSTL AFEYGPMPLV QIKFEDTNTE IPVSTDAVRF 120
121 GRSFKGQLNT VVFFRIIRRN KDPKIFSKEL WLNIVNIILT LYEDLILSPD IFPDLQKRLK 180
181 LSNLPKPSPE ISINKSKESK GLLSTFASYL KGDEEPTEEE IKSSKKAMEC IKSSNIAASV 240
241 FGNESNITAD LIKTLLDSAK TEKNADNSRY FEAELLFIIE LTIALFLFCK EEKELGKFIL 300
301 QKVFQLSHTK GLTKRTVRRM LT
|
| Detection Method: | |
| Confidence: | 9.55 |
| Match: | 1qgkA |
| Description: | Importin beta |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1115-1320] |
1 11 21 31 41 51
| | | | | |
1 YKILLISLCA DQTEYLSKLI NDELLKKGDI FTQKFFATNQ GKEFLKRLFS LTESEFYRGF 60
61 LLGNENFWKF LRKVTAMKEQ SESIFEYLNE SIKTDSNILT NENFMWVLGL LDEISSMGAV 120
121 GNHWEIEYKK LTESGHKIDK ENPYKKSIEL SLKSIQLTSH LLEDNNDLRK NEIFAIIQAL 180
181 AHQCINPCKQ ISEFAVVTLE QTLINK
|
| Detection Method: | |
| Confidence: | 9.55 |
| Match: | 1qgkA |
| Description: | Importin beta |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ARF guanyl-nucleotide exchange factor activity | 6.57705646633597 | bayes_pls_golite062009 |
| GTPase regulator activity | 3.37865780899325 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 3.23621073985922 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 3.11224105598265 | bayes_pls_golite062009 |
| small GTPase regulator activity | 2.75174745190211 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.95578809138334 | bayes_pls_golite062009 |
| binding | 1.3334812784277 | bayes_pls_golite062009 |
| protein binding | 0.917306986228715 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.909190013421997 | bayes_pls_golite062009 |
| phosphoinositide binding | 0.0750646331148792 | bayes_pls_golite062009 |
| phospholipid binding | 0.0172309833091902 | bayes_pls_golite062009 |
|
Region A: Residues: [1321-1404] |
1 11 21 31 41 51
| | | | | |
1 IEIPTNEMES VEELIEGGLL PLLNSSETQE DQKILISSIL TIISNVYLHY LKLGKTSNET 60
61 FLKILSIFNK FVEDSDIEKK LQQL
|
| Detection Method: | |
| Confidence: | 9.55 |
| Match: | 1qgkA |
| Description: | Importin beta |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1405-1459] |
1 11 21 31 41 51
| | | | | |
1 ILDKKSIEKG NGSSSHGSAH EQTPESNDVE IEATAPIDDN TDDDNKPKLS DVEKD
|
| Detection Method: | |
| Confidence: | 7.21 |
| Match: | 1ao6A |
| Description: | Serum albumin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1177-1252] |
1 11 21 31 41 51
| | | | | |
1 GNENFWKFLR KVTAMKEQSE SIFEYLNESI KTDSNILTNE NFMWVLGLLD EISSMGAVGN 60
61 HWEIEYKKLT ESGHKI
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1253-1459] |
1 11 21 31 41 51
| | | | | |
1 DKENPYKKSI ELSLKSIQLT SHLLEDNNDL RKNEIFAIIQ ALAHQCINPC KQISEFAVVT 60
61 LEQTLINKIE IPTNEMESVE ELIEGGLLPL LNSSETQEDQ KILISSILTI ISNVYLHYLK 120
121 LGKTSNETFL KILSIFNKFV EDSDIEKKLQ QLILDKKSIE KGNGSSSHGS AHEQTPESND 180
181 VEIEATAPID DNTDDDNKPK LSDVEKD
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
