Protein: | SAC7 |
Organism: | Saccharomyces cerevisiae |
Length: | 654 amino acids |
Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAC7.
Description | E-value | Query Range |
Subject Range |
|
0.0 | [1..654] | [1..654] |
|
3.0E-67 | [89..507] | [323..781] |
|
1.0E-66 | [89..507] | [323..781] |
|
9.0E-62 | [19..319] | [138..443] |
Region A: Residues: [1-68] |
1 11 21 31 41 51 | | | | | | 1 MPNNTLKQGS KIENVSPSKG HVPSFWKQFI NNPKSMSSEN ITVPRSPTSL SRNAQPTTLK 60 61 RPPLSSRP |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
MCM Score |
SCOP Match |
SCOP Description | ||
View | Download | 0.423 | a.4.1 | Homeodomain-like |
View | Download | 0.528 | d.58.17 | Metal-binding domain |
View | Download | 0.608 | a.56.1 | CO dehydrogenase ISP C-domain like |
View | Download | 0.477 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
View | Download | 0.381 | d.64.1 | eIF1-like |
View | Download | 0.362 | a.4.1 | Homeodomain-like |
View | Download | 0.349 | a.4.5 | "Winged helix" DNA-binding domain |
View | Download | 0.319 | f.14.1 | Voltage-gated potassium channels |
View | Download | 0.295 | a.60.2 | RuvA domain 2-like |
View | Download | 0.289 | a.4.1 | Homeodomain-like |
View | Download | 0.258 | a.56.1 | CO dehydrogenase ISP C-domain like |
View | Download | 0.255 | a.55.1 | IHF-like DNA-binding proteins |
View | Download | 0.252 | a.3.1 | Cytochrome c |
View | Download | 0.243 | a.5.2 | UBA-like |
View | Download | 0.239 | a.22.1 | Histone-fold |
View | Download | 0.231 | f.14.1 | Voltage-gated potassium channels |
View | Download | 0.225 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
View | Download | 0.224 | a.3.1 | Cytochrome c |
View | Download | 0.217 | a.4.5 | "Winged helix" DNA-binding domain |
Term | Confidence | Notes |
Rho GTPase activator activity | 4.58620967349979 | bayes_pls_golite062009 |
Rac GTPase activator activity | 3.29568423512865 | bayes_pls_golite062009 |
GTPase regulator activity | 2.70614727793157 | bayes_pls_golite062009 |
nucleoside-triphosphatase regulator activity | 2.68579854252375 | bayes_pls_golite062009 |
binding | 2.15139804299723 | bayes_pls_golite062009 |
guanyl-nucleotide exchange factor activity | 2.06038764955701 | bayes_pls_golite062009 |
enzyme regulator activity | 1.9750017471254 | bayes_pls_golite062009 |
small GTPase regulator activity | 1.95738547986197 | bayes_pls_golite062009 |
transcription regulator activity | 1.40452907766862 | bayes_pls_golite062009 |
protein binding | 1.29100556128076 | bayes_pls_golite062009 |
Ras GTPase activator activity | 1.09070479183477 | bayes_pls_golite062009 |
cytoskeletal protein binding | 1.03886555863373 | bayes_pls_golite062009 |
Ras guanyl-nucleotide exchange factor activity | 0.958295643211986 | bayes_pls_golite062009 |
nucleic acid binding | 0.924382263852473 | bayes_pls_golite062009 |
actin binding | 0.834823471990077 | bayes_pls_golite062009 |
DNA binding | 0.748649183906122 | bayes_pls_golite062009 |
GTPase activator activity | 0.717730683557543 | bayes_pls_golite062009 |
enzyme activator activity | 0.298334474872045 | bayes_pls_golite062009 |
catalytic activity | 0.194464246602439 | bayes_pls_golite062009 |
transcription factor activity | 0.124467557925988 | bayes_pls_golite062009 |
Region A: Residues: [69-221] |
1 11 21 31 41 51 | | | | | | 1 YSYNTPTKDR KSFSKSAKQN NNNNNANSGT SPHAEFKNYR DMFLSNRNGF TGRVFGVTLA 60 61 ESLSVASAEV IVQSELVSFG RIPIVVAKCG AYLKANGLET SGIFRIAGNG KRVKALQYIF 120 121 SSPPDYGTKF NDWETYTVHD VASLLRRYLN NLA |
Detection Method: | |
Confidence: | 89.30103 |
Match: | 1rgp__ |
Description: | p50 RhoGAP domain |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [222-324] |
1 11 21 31 41 51 | | | | | | 1 EPLIPLSLYE QFRNPLRSRP RILRHMLTHE VSHPNANKTN NVTVKSSRQN YNDDGANDGD 60 61 IEKEDAKDDE EKRRRKIRHK RRLTRDIRAA IKEYEELFVT LSN |
Detection Method: | |
Confidence: | 89.30103 |
Match: | 1rgp__ |
Description: | p50 RhoGAP domain |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [325-434] |
1 11 21 31 41 51 | | | | | | 1 DTKQLTIYLL DLLSLFARQS QFNLMSGRNL AAIFQPSILS HPQHDMDPKE YELSRLVVEF 60 61 LIEYSYKLLP HLLKLAKREQ QERLSTENKK NNGDKQKTDP IEIPKITSSD |
Detection Method: | |
Confidence: | 10.82 |
Match: | 1pbwA |
Description: | p85 alpha subunit RhoGAP domain |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [435-654] |
1 11 21 31 41 51 | | | | | | 1 SPPIVSSNKN PPAIDNNNKL DHTTLSPIST SIPENSSDLQ TSKMLKPPKQ RRPHSKSFGS 60 61 TPVPPDVIAS NKRRTSLFPW LHKPGILSDT GDNGDLTATE AEGDDYEEEN VDPYGQSPSS 120 121 VHSGSLPKQH YLPIPRMNRS LSGNSTNSSF NTRPISMILT SGNDNSADQL ELLSNTHSNN 180 181 ERSNALPLTE DDGDERNSRS RKRESWFQRL TSRSGSANRA |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.