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View Structure Prediction Details

Protein: YDR333C
Organism: Saccharomyces cerevisiae
Length: 723 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDR333C.

Description E-value Query
Range
Subject
Range
gi|207346436 - gi|207346436|gb|EDZ72929.1| YDR333Cp-like protein [Saccharomyces cerevisiae AWRI1631]
YDR333C - Putative protein of unknown function
RQC1_YEAST - Ribosome quality control complex subunit 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) ...
gi|151942309 - gi|151942309|gb|EDN60665.1| conserved protein [Saccharomyces cerevisiae YJM789]
0.0 [1..713] [1..713]
gi|167773407 - gi|167773407|gb|ABZ92138.1| transcription factor 25 (basic helix-loop-helix) [synthetic construct]
TCF25 - transcription factor 25 (basic helix-loop-helix)
0.0 [1..666] [1..591]
FK26_MOUSE, FKS2... - (Q8R3L2) Protein FKSG26, (Q8R3L2) FKSG26 protein
0.0 [1..666] [1..591]
SPAC1142.01 - DUF654 family protein
gi|19115177 - gi|19115177|ref|NP_594265.1| hypothetical protein SPAC17G6.18 [Schizosaccharomyces pombe 972h-]
0.0 [1..670] [12..571]
CG7927-PA, FBpp0... - This gene is referred to in FlyBase by the symbol Dmel\CG7927 (CG7927, FBgn0027549). It is a protein...
gi|220953660 - gi|220953660|gb|ACL89373.1| CG7927-PA [synthetic construct]
0.0 [116..663] [22..567]
CE18019 - status:Partially_confirmed UniProt:P90919 protein_id:CAB03183.1
0.0 [274..663] [89..454]
gi|76363816 - gi|76363816|ref|XP_888619.1| hypothetical protein [Leishmania major strain Friedlin]
gi|12311834 - gi|12311834|emb|CAC22652.1| hypothetical protein L8032.10 [Leishmania major]
8.0E-98 [57..490] [122..511]

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Predicted Domain #1
Region A:
Residues: [1-298]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRALRRLQ DDNALLESLL SNSNANKMTS GKSTAGNIQK RENIFSMMNN VRDSDNSTDE  60
   61 GQMSEQDEEA AAAGERDTQS NGQPKRITLA SKSSRRKKNK KAKRKQKNHT AEAAKDKGSD 120
  121 DDDDDEEFDK IIQQFKKTDI LKYGKTKNDD TNEEGFFTAS EPEEASSQPW KSFLSLESDP 180
  181 GFTKFPISCL RHSCKFFQND FKKLDPHTEF KLLFDDISPE SLEDIDSMTS TPVSPQQLKQ 240
  241 IQRLKRLIRN WGGKDHRLAP NGPGMHPQHL KFTKIRDDWI PTQRGELSMK LLSSDDLL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [299-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DWQLWERPLD WKDVIQNDVS QWQKFISFYK FEPLNSDLSK KSMMDFYLSV IVHPD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.00861212399414 bayes_pls_golite062009
protein binding 1.51322932625387 bayes_pls_golite062009
transcription regulator activity 0.92511049170437 bayes_pls_golite062009
nucleic acid binding 0.777329345097548 bayes_pls_golite062009
DNA binding 0.67447901722682 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [354-477]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HEALINLISS KFPYHVPGLL QVALIFIRQG DRSNTNGLLQ RALFVFDRAL KANIIFDSLN  60
   61 CQLPYIYFFN RQFYLAIFRY IQSLAQRGVI GTASEWTKVL WSLSPLEDPL GCRYFLDHYF 120
  121 LLNN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.73
Match: 1fchA
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [478-608]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYQYIIELSN SPLMNCYKQW NTLGFSLAVV LSFLRINEMS SARNALLKAF KHHPLQLSEL  60
   61 FKEKLLGDHA LTKDLSIDGH SAENLELKAY MARFPLLWNR NEEVTFLHDE MSSILQDYHR 120
  121 GNVTIDSNDG Q

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.73
Match: 1fchA
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [609-723]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DHNNINNLQS PFFIAGIPIN LLRFAILSEE SSVMAAIPSF IWSDNEVYEF DVLPPMPTSK  60
   61 ESIEVVENIK TFINEKDLAV LQAERMQDED LLNQIRQISL QQYIHENEES NENEG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle