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View Structure Prediction Details

Protein: YSP2
Organism: Saccharomyces cerevisiae
Length: 1438 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YSP2.

Description E-value Query
Range
Subject
Range
YHR080C - Protein of unknown function that may interact with ribosomes, based on co-purification experiments; ...
LAM4_YEAST - Membrane-anchored lipid-binding protein LAM4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
0.0 [159..1425] [87..1334]
gi|6330416 - gi|6330416|dbj|BAA86515.1| KIAA1201 protein [Homo sapiens]
0.0 [539..1056] [31..601]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [445..981] [2..547]
BAGP1_ARATH - BAG-associated GRAM protein 1 OS=Arabidopsis thaliana GN=BAGP1 PE=1 SV=1
0.0 [524..1040] [106..594]
gi|26665873, gi|... - gi|26665873|ref|NP_082174.2| GRAM domain containing 1A [Mus musculus], gi|17391321|gb|AAH18554.1| Gr...
0.0 [632..1012] [2..459]
SPBC20F10.07 - GRAM domain protein
YGZ7_SCHPO - Uncharacterized membrane protein C20F10.07 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN...
0.0 [592..1013] [138..593]

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Predicted Domain #1
Region A:
Residues: [1-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRDEATRKKR SFSDGHFFKK LKLMSRKKQP VMERSKTTRT RKESTNSAAK SSLSLRRANN  60
   61 GRKTIAKRRV LTDIGSTNEG VAGNSGSNSP AQYSHTPHFS DSIPPLPLEL PDIVSIRSSR 120
  121 SHISNKSNKN KHGIDLTFIP RRSLQNSKAG LKKPNTSPQG YFNIPVTIDR ASEKVKHTDT 180
  181 KNTFNSSSSE NERPVLSILQ KDDSQSSSHP AIDSMSAPNN INNNNDIENS SNSLFDTILS 240
  241 IAHSAISHVP KISALNTEIQ REFSHSGESH TGSTRHPYFH IHHAQQQHPL SQQQGPLPVS 300
  301 ENANQNPNDT VLIHSPSANT AHRSSSFLRH LDYLLSPTSG PASDKHTQVE EGDDEEELSP 360
  361 LSKAFLSPST QLVPTNTSTT PLSGSLTPNN RNVNANSNSE TENDNDRDDR SNVGKVKFQP 420
  421 LKVHEPAIST FGKGNLTLEA VAGSSDIDNT TIDLDENNTN NNPNASSTN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [470-621]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSHISKSNVN NNLGPKELNT SYRNSTYIDM ARFENSQSNL SSHRARSKTL PANKALENAV  60
   61 GDEGNSKRNS RYSSYSNDMA FDDADERKFR SMSKKFLNRR SFSPSNLGNK VIPGINLRNS 120
  121 FNKNRNSSSD FFSTNQGQQM PRTSTAGSGN IH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [622-770]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIMGLDSGND DFKLEGIEYA SEKKNSEFHT LFKDCDINPN EKLIVDHSCA LSRDILLQGR  60
   61 MYISDAHIGF FSNILGWVST VFIPFKEIVQ IEKKTTAGIF PNGIVIDTLH TKYIFASFMS 120
  121 RDATFDLITD VWNQIILGKK YRNGFGNND

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 26.267606
Match: PF02893
Description: GRAM domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.445 0.402 apoptosis d.19.1 MHC antigen-recognition domain
View Download 0.501 0.235 apoptosis b.29.1 Concanavalin A-like lectins/glucanases
View Download 0.466 0.079 mitochondrion b.60.1 Lipocalins
View Download 0.449 0.001 apoptosis c.57.1 Molybdenum cofactor biosynthesis proteins
View Download 0.436 N/A N/A c.57.1 Molybdenum cofactor biosynthesis proteins

Predicted Domain #4
Region A:
Residues: [771-829]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGTISDSSSA FFDDSDDNDD DGDLDDDDPD INSTDMTSSD DIDADVFNES NDLGKNQKS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.391 a.4.1 Homeodomain-like
View Download 0.360 a.4.1 Homeodomain-like
View Download 0.265 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.238 a.4.5 "Winged helix" DNA-binding domain
View Download 0.237 a.60.1 SAM/Pointed domain
View Download 0.211 a.4.1 Homeodomain-like

Predicted Domain #5
Region A:
Residues: [830-916]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNYLLGPNKH SPTTADFKPS NNDHLVIEAN INAPLGKVVN LLYGEDVSYY ERILKAQKNF  60
   61 EISPIPNNFL TKKIRDYAYT KPLSGSI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.505 0.004 apoptosis d.95.2 Homing endonucleases
View Download 0.493 0.001 apoptosis d.58.12 eEF-1beta-like
View Download 0.481 0.001 apoptosis d.212.1 TolA/TonB C-terminal domain
View Download 0.505 N/A N/A d.95.2 Homing endonucleases
View Download 0.504 N/A N/A d.95.2 Homing endonucleases
View Download 0.493 N/A N/A d.58.12 eEF-1beta-like
View Download 0.481 N/A N/A d.212.1 TolA/TonB C-terminal domain
View Download 0.476 N/A N/A d.95.2 Homing endonucleases
View Download 0.458 N/A N/A d.94.2 Putative transcriptional regulator TM1602, C-terminal domain
View Download 0.456 N/A N/A d.199.1 DNA-binding C-terminal domain of the transcription factor MotA
View Download 0.443 N/A N/A d.58.10 Acylphosphatase-like
View Download 0.440 N/A N/A b.71.1 Glycosyl hydrolase domain
View Download 0.421 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.416 N/A N/A d.58.42 N-utilization substance G protein NusG, N-terminal domain
View Download 0.387 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.387 N/A N/A d.68.3 SirA-like
View Download 0.378 N/A N/A c.5.1 MurCD N-terminal domain
View Download 0.358 N/A N/A d.68.3 SirA-like
View Download 0.325 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.322 N/A N/A d.95.1 Glucose permease domain IIB
View Download 0.316 N/A N/A d.129.1 TATA-box binding protein-like
View Download 0.314 N/A N/A d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.310 N/A N/A d.58.10 Acylphosphatase-like
View Download 0.301 N/A N/A b.71.1 Glycosyl hydrolase domain
View Download 0.298 N/A N/A d.58.5 GlnB-like
View Download 0.298 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.296 N/A N/A b.61.4 Quinohemoprotein amine dehydrogenase A chain, domain 3
View Download 0.294 N/A N/A d.58.2 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
View Download 0.294 N/A N/A d.58.17 Metal-binding domain
View Download 0.293 N/A N/A d.52.7 Ribosome-binding factor A, RbfA
View Download 0.282 N/A N/A d.89.1 Origin of replication-binding domain, RBD-like
View Download 0.274 N/A N/A c.44.2 Enzyme IIB-cellobiose
View Download 0.260 N/A N/A d.74.1 Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)
View Download 0.256 N/A N/A d.58.17 Metal-binding domain
View Download 0.244 N/A N/A d.58.24 CheY-binding domain of CheA
View Download 0.236 N/A N/A d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.226 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.224 N/A N/A d.52.1 Alpha-lytic protease prodomain
View Download 0.214 N/A N/A d.58.1 4Fe-4S ferredoxins
View Download 0.203 N/A N/A d.52.3 Prokaryotic type KH domain (KH-domain type II)

Predicted Domain #6
Region A:
Residues: [917-1004]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPSKTKCLIT DTLEHYDLED YVKVLSITKN PDVPSGNIFS VKTVFLFSWD KNNSTKLTVY  60
   61 NSVDWTGKSW IKSMIEKGTF DGVADTTK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.523 d.129.3 Bet v1-like
View Download 0.499 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.523 d.129.3 Bet v1-like
View Download 0.502 d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
View Download 0.502 d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
View Download 0.499 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.485 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.485 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.450 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.433 b.1.5 Transglutaminase, two C-terminal domains
View Download 0.427 d.17.1 Cystatin/monellin
View Download 0.393 d.58.12 eEF-1beta-like
View Download 0.376 b.1.18 E set domains
View Download 0.371 d.50.1 dsRNA-binding domain-like
View Download 0.366 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.359 b.1.5 Transglutaminase, two C-terminal domains
View Download 0.335 d.58.8 Viral DNA-binding domain
View Download 0.320 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.311 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.307 d.17.4 NTF2-like
View Download 0.305 d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.297 a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.296 d.58.7 RNA-binding domain, RBD
View Download 0.291 d.17.4 NTF2-like
View Download 0.281 d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.279 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.277 b.1.12 Purple acid phosphatase, N-terminal domain
View Download 0.268 b.61.1 Avidin/streptavidin
View Download 0.258 d.130.1 S-adenosylmethionine synthetase
View Download 0.256 d.58.19 Bacterial exopeptidase dimerisation domain
View Download 0.250 d.17.4 NTF2-like
View Download 0.248 d.17.4 NTF2-like
View Download 0.245 b.40.4 Nucleic acid-binding proteins
View Download 0.244 b.24.1 Hyaluronate lyase-like, C-terminal domain
View Download 0.231 b.16.1 Ecotin, trypsin inhibitor
View Download 0.231 d.50.1 dsRNA-binding domain-like
View Download 0.224 g.18.1 Complement control module/SCR domain
View Download 0.218 d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.212 b.1.5 Transglutaminase, two C-terminal domains
View Download 0.208 d.107.1 Ran-binding protein mog1p
View Download 0.207 d.52.3 Prokaryotic type KH domain (KH-domain type II)

Predicted Domain #7
Region A:
Residues: [1005-1263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IMISEIKKIL SDEDSNINSK HQASNNESEE EIINLPTIGP PVHDPTEPDF QKGKDDTVID  60
   61 EKINIPVPLG TVFSLLYGDD TSYIKKIIEN QNNFNVCDIP KFVNNAREIT YTKKLNNSFG 120
  121 PKQTKCIVTE TIEHMDLNSF FMVKQIVRSP DVPYGSSFSV HTRFFYSWGD HNTTNMKVVT 180
  181 NVVWTGKSML KGTIEKGSID GQRSSTKQLV DDLKKIISNA SSTKKKSRRR GKTVNKRKSS 240
  241 PSTIKNEKNE ENFEDTSTK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1264-1438]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSFFSAFSML QQVNITSVQG IMTIISFFIC LIFFFRLLFH SKNTSNIQII TPGTILINGN  60
   61 EYNYVPNFKT LYHVYEDNII KDARRKDSNK NNIVTDTEGL IWDWLIDRGN GTVQNSVLSN 120
  121 HIKESNNKKV KLVNGVSDHK IQQLVESIKI TELQLQEMKE LLAQTDNTSA TNQLL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1305-1438]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNTSNIQIIT PGTILINGNE YNYVPNFKTL YHVYEDNIIK DARRKDSNKN NIVTDTEGLI  60
   61 WDWLIDRGNG TVQNSVLSNH IKESNNKKVK LVNGVSDHKI QQLVESIKIT ELQLQEMKEL 120
  121 LAQTDNTSAT NQLL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle