






| Protein: | ECM18 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 453 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ECM18.
| Description | E-value | Query Range |
Subject Range |
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2.0E-91 | [1..453] | [1..453] |
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9.0E-55 | [9..448] | [28..423] |
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3.0E-51 | [107..447] | [6..314] |
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4.0E-51 | [114..447] | [16..320] |
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1.0E-50 | [81..453] | [205..550] |
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Region A: Residues: [1-77] |
1 11 21 31 41 51
| | | | | |
1 MLLIKRYLMD PESLRRQIMN VYKCYMWKRA FHSNRSLLEV KRREKSLQRK ILERILRPKE 60
61 ENAVKKSGFK LWSSHLN
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Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.909 | a.112.1 | Description not found. |
| Term | Confidence | Notes |
| catalytic activity | 1.39629727416851 | bayes_pls_golite062009 |
| phospholipase activity | 1.05835015160042 | bayes_pls_golite062009 |
| lipase activity | 0.849473630399459 | bayes_pls_golite062009 |
| carboxylesterase activity | 0.424330502936163 | bayes_pls_golite062009 |
| binding | 0.401633301499824 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 0.264183693934251 | bayes_pls_golite062009 |
| protein binding | 0.0473186402188429 | bayes_pls_golite062009 |
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Region A: Residues: [78-453] |
1 11 21 31 41 51
| | | | | |
1 NPHKTYMRLE ELQRRIMEEV HVEGIKKNDK LFNEINQWHF QNENTSTVRT PTLLIHGYAA 60
61 SSMSFFRNYP GLSKHIRNLY SIDMPASGLS SVPSLEINTT TPLPLDIKFI GENKFKVPYT 120
121 INANHNKFVI QMYEDFYLDR IEQWRIDNKL GKMNVVGHSF GGYLSFKYAV KYPNSVNKLC 180
181 LVSPLGVERN IWSVNNNFHS NTLYTIDFKN PNSKFYSKRN MIPKYLFEQQ FHILRMMGPL 240
241 GAKLCWNYIM AAYSRVPSLA YKEYIFELFY GKGGIPEVTT DIFKALFSRC ILAKDPLMDS 300
301 LQYLNVKKLL IVYGQYDWMN KKAGMFMVKE LNNLKNCLEG ASYLEIPSSG HNLFLDNPES 360
361 FNQSIVSFLS DETKSP
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| Detection Method: | |
| Confidence: | 49.09691 |
| Match: | 1cqzA_ |
| Description: | Epoxide hydrolase, N-terminal domain; Mammalian epoxide hydrolase, C-terminal domain |
Matching Structure (courtesy of the PDB):![]() |
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