| Protein: | ECM18 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 453 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ECM18.
| Description | E-value | Query Range |
Subject Range |
|
|
2.0E-91 | [1..453] | [1..453] |
|
|
9.0E-55 | [9..448] | [28..423] |
|
|
3.0E-51 | [107..447] | [6..314] |
|
|
4.0E-51 | [114..447] | [16..320] |
|
|
1.0E-50 | [81..453] | [205..550] |
|
Region A: Residues: [1-77] |
1 11 21 31 41 51
| | | | | |
1 MLLIKRYLMD PESLRRQIMN VYKCYMWKRA FHSNRSLLEV KRREKSLQRK ILERILRPKE 60
61 ENAVKKSGFK LWSSHLN
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.909 | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.714 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.909 | a.112.1 | Description not found. |
| View | Download | 0.684 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.640 | a.112.1 | Description not found. |
| View | Download | 0.628 | a.112.1 | Description not found. |
| View | Download | 0.617 | a.24.4 | Hemerythrin |
| View | Download | 0.588 | a.64.1 | Saposin |
| View | Download | 0.579 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.579 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.579 | a.77.1 | DEATH domain |
| View | Download | 0.546 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.533 | a.112.1 | Description not found. |
| View | Download | 0.530 | a.64.1 | Saposin |
| View | Download | 0.510 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.497 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.492 | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.475 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.470 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.467 | a.69.3 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain |
| View | Download | 0.459 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.441 | a.112.1 | Description not found. |
| View | Download | 0.437 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.418 | a.112.1 | Description not found. |
| View | Download | 0.410 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.400 | a.2.3 | Chaperone J-domain |
| View | Download | 0.390 | a.112.1 | Description not found. |
| View | Download | 0.390 | a.112.1 | Description not found. |
| View | Download | 0.387 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.370 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.367 | g.2.2 | Neurotoxin B-IV |
| View | Download | 0.364 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.356 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.350 | a.112.1 | Description not found. |
| View | Download | 0.350 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.348 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.347 | a.74.1 | Cyclin-like |
| View | Download | 0.342 | g.2.2 | Neurotoxin B-IV |
| View | Download | 0.338 | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.338 | c.72.1 | Ribokinase-like |
| View | Download | 0.336 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.322 | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.320 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.304 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.302 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.301 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.295 | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.289 | d.130.1 | S-adenosylmethionine synthetase |
| View | Download | 0.287 | a.126.1 | Serum albumin-like |
| View | Download | 0.287 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.286 | a.77.1 | DEATH domain |
| View | Download | 0.281 | a.74.1 | Cyclin-like |
| View | Download | 0.280 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.278 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.277 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.275 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.274 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.272 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.269 | a.112.1 | Description not found. |
| View | Download | 0.267 | d.74.3 | RBP11-like subunits of RNA polymerase |
| View | Download | 0.263 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.260 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.259 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.258 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.256 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.254 | a.143.1 | RNA polymerase omega subunit |
| View | Download | 0.253 | a.126.1 | Serum albumin-like |
| View | Download | 0.252 | a.126.1 | Serum albumin-like |
| View | Download | 0.250 | a.126.1 | Serum albumin-like |
| View | Download | 0.249 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.249 | a.2.4 | Theta subunit of DNA polymerase III |
| View | Download | 0.248 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.248 | a.101.1 | Uteroglobin-like |
| View | Download | 0.237 | a.64.1 | Saposin |
| View | Download | 0.237 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.236 | a.77.1 | DEATH domain |
| View | Download | 0.235 | a.39.1 | EF-hand |
| View | Download | 0.230 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.229 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.229 | a.22.1 | Histone-fold |
| View | Download | 0.226 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.225 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.224 | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.224 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.223 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.222 | a.2.3 | Chaperone J-domain |
| View | Download | 0.220 | d.78.1 | RPB5-like RNA polymerase subunit |
| View | Download | 0.220 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.219 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.217 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.216 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.216 | a.58.1 | Chemotaxis receptor methyltransferase CheR, N-terminal domain |
| View | Download | 0.216 | a.112.1 | Description not found. |
| View | Download | 0.213 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.211 | a.77.1 | DEATH domain |
| View | Download | 0.209 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.208 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.206 | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.205 | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| Term | Confidence | Notes |
| catalytic activity | 1.39629727416851 | bayes_pls_golite062009 |
| phospholipase activity | 1.05835015160042 | bayes_pls_golite062009 |
| lipase activity | 0.849473630399459 | bayes_pls_golite062009 |
| carboxylesterase activity | 0.424330502936163 | bayes_pls_golite062009 |
| binding | 0.401633301499824 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 0.264183693934251 | bayes_pls_golite062009 |
| protein binding | 0.0473186402188429 | bayes_pls_golite062009 |
|
Region A: Residues: [78-453] |
1 11 21 31 41 51
| | | | | |
1 NPHKTYMRLE ELQRRIMEEV HVEGIKKNDK LFNEINQWHF QNENTSTVRT PTLLIHGYAA 60
61 SSMSFFRNYP GLSKHIRNLY SIDMPASGLS SVPSLEINTT TPLPLDIKFI GENKFKVPYT 120
121 INANHNKFVI QMYEDFYLDR IEQWRIDNKL GKMNVVGHSF GGYLSFKYAV KYPNSVNKLC 180
181 LVSPLGVERN IWSVNNNFHS NTLYTIDFKN PNSKFYSKRN MIPKYLFEQQ FHILRMMGPL 240
241 GAKLCWNYIM AAYSRVPSLA YKEYIFELFY GKGGIPEVTT DIFKALFSRC ILAKDPLMDS 300
301 LQYLNVKKLL IVYGQYDWMN KKAGMFMVKE LNNLKNCLEG ASYLEIPSSG HNLFLDNPES 360
361 FNQSIVSFLS DETKSP
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| Detection Method: | |
| Confidence: | 49.09691 |
| Match: | 1cqzA_ |
| Description: | Epoxide hydrolase, N-terminal domain; Mammalian epoxide hydrolase, C-terminal domain |
Matching Structure (courtesy of the PDB): |
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