YRC Public Data Repository - Protein Structure Prediction

Protein:	PST2
Organism:	Saccharomyces cerevisiae
Length:	198 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PST2.

Description	E-value	Query Range	Subject Range
gi\|4454993 - gi\|4454993\|gb\|AAD21025.1\| 1,4-benzoquinone reductase [Phanerochaete chrysosporium]	6.0E-51	[1..197]	[1..198]
PST2_YEAST - Protoplast secreted protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PST2 PE=1 ... PST2 - Protein with similarity to members of a family of flavodoxin-like proteins; induced by oxidative str... ORFP:3847 - YDR032C, Contig c134 8459-9055 reverse complement gi\|190404996 - gi\|190404996\|gb\|EDV08263.1\| protoplast secreted protein 2 precursor [Saccharomyces cerevisiae RM11-1... gi\|207346835 - gi\|207346835\|gb\|EDZ73209.1\| YDR032Cp-like protein [Saccharomyces cerevisiae AWRI1631]	1.0E-50	[1..198]	[1..198]
gi\|166010804, gi... - gi\|166010804\|ref\|ZP_02231702.1\| flavoprotein WrbA [Yersinia pestis biovar Antiqua str. E1979001], gi... gi\|165938712, gi... - gi\|165938712\|ref\|ZP_02227267.1\| flavoprotein WrbA [Yersinia pestis biovar Orientalis str. IP275], gi... gi\|165926054, gi... - gi\|165926054\|ref\|ZP_02221886.1\| flavoprotein WrbA [Yersinia pestis biovar Orientalis str. F1991016],... NQOR_YERP3 - NAD(P)H dehydrogenase (quinone) OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=Yp... NQOR_YERPG - NAD(P)H dehydrogenase (quinone) OS=Yersinia pestis bv. Antiqua (strain Angola) GN=YpAngola_A2043 PE=... gi\|149366197, gi... - gi\|149366197\|ref\|ZP_01888232.1\| trp repressor binding protein [Yersinia pestis CA88-4125], gi\|149292... gi\|167425826, gi... - gi\|167425826\|ref\|ZP_02317579.1\| flavoprotein WrbA [Yersinia pestis biovar Mediaevalis str. K1973002]... WRBA_YERPS - Flavoprotein wrbA OS=Yersinia pseudotuberculosis GN=wrbA PE=3 SV=1 NQOR_YERPP - NAD(P)H dehydrogenase (quinone) OS=Yersinia pestis (strain Pestoides F) GN=YPDSF_1268 PE=3 SV=1 gi\|167419964, gi... - gi\|167419964\|ref\|ZP_02311717.1\| flavoprotein WrbA [Yersinia pestis biovar Orientalis str. MG05-1020]... gi\|167401086, gi... - gi\|167401086\|ref\|ZP_02306589.1\| flavoprotein WrbA [Yersinia pestis biovar Antiqua str. UG05-0454], g... gi\|166207829, gi... - gi\|166210649\|ref\|ZP_02236684.1\| flavoprotein WrbA [Yersinia pestis biovar Antiqua str. B42003004], g... gi\|229693580, gi... - gi\|229897243\|ref\|ZP_04512399.1\| trp repressor binding protein [Yersinia pestis biovar Orientalis str... gi\|229896306, gi... - gi\|229896306\|ref\|ZP_04511476.1\| trp repressor binding protein [Yersinia pestis Pestoides A], gi\|2297... NQOR_YERPN - NAD(P)H dehydrogenase (quinone) OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=YPN_2266 PE=3 SV... NQOR_YERPA - NAD(P)H dehydrogenase (quinone) OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=YPA_1236 PE=3 SV=... gi\|229689011, gi... - gi\|229897970\|ref\|ZP_04513121.1\| trp repressor binding protein [Yersinia pestis biovar Orientalis str... gi\|218928976, gi... - gi\|218928976\|ref\|YP_002346851.1\| TrpR binding protein WrbA [Yersinia pestis CO92], gi\|16122108\|ref\|N... NQOR_YERPS - NAD(P)H dehydrogenase (quinone) OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=YPTB17... NQOR_YERPE - NAD(P)H dehydrogenase (quinone) OS=Yersinia pestis GN=YPO1857 PE=3 SV=1 NQOR_YERPB - NAD(P)H dehydrogenase (quinone) OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=YPTS_18... NQOR_YERPY - NAD(P)H dehydrogenase (quinone) OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=YPK_23...	4.0E-50	[1..197]	[1..196]
WRBA_SALTI - Flavoprotein wrbA OS=Salmonella typhi GN=wrbA PE=3 SV=3 NQOR_SALTI - NAD(P)H dehydrogenase (quinone) OS=Salmonella typhi GN=STY1155 PE=3 SV=3 gi\|213163116 - gi\|213163116\|ref\|ZP_03348826.1\| TrpR binding protein WrbA [Salmonella enterica subsp. enterica serov... gi\|29142232, gi\|... - gi\|29142232\|ref\|NP_805574.1\| TrpR binding protein WrbA [Salmonella enterica subsp. enterica serovar ... gi\|16759997 - gi\|16759997\|ref\|NP_455614.1\| TrpR binding protein WrbA [Salmonella enterica subsp. enterica serovar ... gi\|214003496 - gi\|214003496\|ref\|ZP_03414231.1\| TrpR binding protein WrbA [Salmonella enterica subsp. enterica serov... gi\|213428508 - gi\|213428508\|ref\|ZP_03361258.1\| TrpR binding protein WrbA [Salmonella enterica subsp. enterica serov... gi\|213416804 - gi\|213416804\|ref\|ZP_03349948.1\| TrpR binding protein WrbA [Salmonella enterica subsp. enterica serov... gi\|213648756 - gi\|213648756\|ref\|ZP_03378809.1\| TrpR binding protein WrbA [Salmonella enterica subsp. enterica serov... gi\|213579930 - gi\|213579930\|ref\|ZP_03361756.1\| TrpR binding protein WrbA [Salmonella enterica subsp. enterica serov...	4.0E-50	[1..197]	[1..195]
gi\|30027749, gi\|... - gi\|30027749\|gb\|AAL67860.2\|AF465406_1 NADH:quinone oxidoreductase [Gloeophyllum trabeum], gi\|18308202...	6.0E-50	[2..197]	[58..254]
NQOR_ECOLC - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=EcolC_... gi\|24112417, gi\|... - gi\|24112417\|ref\|NP_706927.1\| TrpR binding protein WrbA [Shigella flexneri 2a str. 301], gi\|24051293\|... NQOR_ECOL6 - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=c1... NQOR_SHIFL - NAD(P)H dehydrogenase (quinone) OS=Shigella flexneri GN=SF1008 PE=3 SV=2 WRBA_ECOLI - Flavoprotein wrbA (Trp repressor-binding protein) - Escherichia coli NQOR_ECO8A - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli O8 (strain IAI1) GN=ECIAI1_1048 PE=3 SV=1 NQOR_ECO45 - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=ECS88_1018 PE=3 S... gi\|30062541, gi\|... - gi\|30062541\|ref\|NP_836712.1\| TrpR binding protein WrbA [Shigella flexneri 2a str. 2457T], gi\|3004078... NQOR_ECO55 - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli (strain 55989 / EAEC) GN=EC55989_1114 PE=3 SV=1 EG11540 - NAD(P)H:quinone oxidoreductase / NAD(P)H:quinone oxidoreductase, type IV NQO; may protect against ox... NQOR_ECO7I - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=ECIAI39_2150 PE=... NQOR_ECOLU - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=ECUMN_118... NQOR_ECOK1 - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli O1:K1 / APEC GN=Ecok1_09050 PE=1 SV=1 gi\|124529132, gi... - gi\|124529132\|ref\|ZP_01700242.1\| flavoprotein WrbA [Escherichia coli B], gi\|124500087\|gb\|EAY47565.1\| ... gi\|254161117, gi... - gi\|254161117\|ref\|YP_003044225.1\| TrpR binding protein WrbA [Escherichia coli B str. REL606], gi\|2539... gi\|253773966, gi... - gi\|254287925\|ref\|YP_003053673.1\| TrpR binding protein WrbA [Escherichia coli BL21(DE3)], gi\|25397723... gi\|242376818, gi... - gi\|251784545\|ref\|YP_002998849.1\| hypothetical protein B21_01014 [Escherichia coli BL21], gi\|24237681... NQOR_ECOBW - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=BWG_0858 PE=3 ... gi\|89107855, gi\|... - gi\|89107855\|ref\|AP_001635.1\| predicted flavoprotein in Trp regulation [Escherichia coli str. K-12 su... gi\|237707016, gi... - gi\|237707016\|ref\|ZP_04537497.1\| trp repressor binding protein [Escherichia sp. 3_2_53FAA], gi\|226898... sp\|B7UNY7\|WRBA_ECO27 - Flavoprotein wrbA OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=wrbA PE=3 SV=1 NQOR_ECOUT - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli (strain UTI89 / UPEC) GN=UTI89_C1067 PE=3 SV=1 gi\|227838795, gi... - gi\|227884043\|ref\|ZP_04001848.1\| multimeric flavodoxin WrbA [Escherichia coli 83972], gi\|227838795\|gb... NQOR_ECOHS - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli O9:H4 (strain HS) GN=EcHS_A1117 PE=3 SV=1 gi\|194413529, gi... - gi\|75210283\|ref\|ZP_00710445.1\| COG0655: Multimeric flavodoxin WrbA [Escherichia coli B171], gi\|19442... gi\|191166896, gi... - gi\|75229925\|ref\|ZP_00716442.1\| COG0655: Multimeric flavodoxin WrbA [Escherichia coli B7A], gi\|191166... gi\|193070808, gi... - gi\|75234363\|ref\|ZP_00718733.1\| COG0655: Multimeric flavodoxin WrbA [Escherichia coli E110019], gi\|19... gi\|191172398, gi... - gi\|75240611\|ref\|ZP_00724528.1\| COG0655: Multimeric flavodoxin WrbA [Escherichia coli F11], gi\|191172... NQOR_ECOL5 - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=ECP_1003 PE=3 ... gi\|75257447, gi\|... - gi\|75257447\|ref\|ZP_00728950.1\| COG0655: Multimeric flavodoxin WrbA [Escherichia coli E22], gi\|193064... NQOR_SHIF8 - NAD(P)H dehydrogenase (quinone) OS=Shigella flexneri serotype 5b (strain 8401) GN=SFV_1016 PE=3 SV=1 gi\|188494733, gi... - gi\|75513454\|ref\|ZP_00735858.1\| COG0655: Multimeric flavodoxin WrbA [Escherichia coli 53638], gi\|1884... WRBA_ECOL6 - Flavoprotein wrbA OS=Escherichia coli O6 GN=wrbA PE=3 SV=2 gi\|194438015, gi... - gi\|83586452\|ref\|ZP_00925086.1\| COG0655: Multimeric flavodoxin WrbA [Escherichia coli 101-1], gi\|1944... NQOR_ECO24 - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=EcE24377A_11... NQOR_ECODH - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli (strain K12 / DH10B) GN=ECDH10B_1076 PE=3 SV=1 NQOR_ECOSM - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=EcSMS35_2120 PE=3 SV... NQOR_ECOSE - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli (strain SE11) GN=ECSE_1066 PE=3 SV=1 EG11540 - NAD(P)H:quinone oxidoreductase / NAD(P)H:quinone oxidoreductase, type IV NQO; may protect against ox... NQOR_ECO27 - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=E2348C_1055 ...	9.0E-50	[1..197]	[1..195]
gi\|189001245, gi... - gi\|189001245\|gb\|EDU70231.1\| NAD(P)H:quinone oxidoreductase, type IV [Escherichia coli O157:H7 str. E... gi\|189372761, gi... - gi\|189372761\|gb\|EDU91177.1\| NAD(P)H:quinone oxidoreductase, type IV [Escherichia coli O157:H7 str. E... gi\|168800637, gi... - gi\|189377075\|gb\|EDU95491.1\| NAD(P)H:quinone oxidoreductase, type IV [Escherichia coli O157:H7 str. E... gi\|195935261 - gi\|195935261\|ref\|ZP_03080643.1\| TrpR binding protein WrbA [Escherichia coli O157:H7 str. EC4024] gi\|168747377, gi... - gi\|188017979\|gb\|EDU56101.1\| NAD(P)H:quinone oxidoreductase, type IV [Escherichia coli O157:H7 str. E... gi\|168754327, gi... - gi\|189358181\|gb\|EDU76600.1\| NAD(P)H:quinone oxidoreductase, type IV [Escherichia coli O157:H7 str. E... gi\|168767504, gi... - gi\|189363095\|gb\|EDU81514.1\| NAD(P)H:quinone oxidoreductase, type IV [Escherichia coli O157:H7 str. E... gi\|187770352, gi... - gi\|187770352\|gb\|EDU34196.1\| NAD(P)H:quinone oxidoreductase, type IV [Escherichia coli O157:H7 str. E... gi\|7649820\|dbj\|B... - trp repressor binding protein [Escherichia coli O157:H7] NQOR_ECO57 - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli O157:H7 GN=Z1423/Z1504 PE=5 SV=3 gi\|208805753, gi... - gi\|208805753\|ref\|ZP_03248090.1\| NAD(P)H:quinone oxidoreductase, type IV [Escherichia coli O157:H7 st... gi\|208815043, gi... - gi\|208815043\|ref\|ZP_03256222.1\| NAD(P)H:quinone oxidoreductase, type IV [Escherichia coli O157:H7 st... gi\|208822086, gi... - gi\|208822086\|ref\|ZP_03262405.1\| NAD(P)H:quinone oxidoreductase, type IV [Escherichia coli O157:H7 st... NQOR_ECO5E - NAD(P)H dehydrogenase (quinone) OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=ECH74115_1242 ...	1.0E-49	[1..197]	[1..195]
NQOR_SALTY - NAD(P)H dehydrogenase (quinone) OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=S... lcl\|NC_016856.1_... - [gene=wraB] [protein=TrpR binding protein WrbA] [protein_id=YP_005236860.1] [location=complement(116... WRBA_SALTY - Flavoprotein wrbA OS=Salmonella typhimurium GN=wrbA PE=3 SV=3 WRBA_SALTY - Flavoprotein wrbA OS=Salmonella typhimurium GN=wrbA PE=3 SV=3 gi\|205328348, gi... - gi\|205328348\|gb\|EDZ15112.1\| NAD(P)H:quinone oxidoreductase, type IV [Salmonella enterica subsp. ente... gi\|167552614, gi... - gi\|205322772\|gb\|EDZ10611.1\| NAD(P)H:quinone oxidoreductase, type IV [Salmonella enterica subsp. ente... NQOR_SALPC - NAD(P)H dehydrogenase (quinone) OS=Salmonella paratyphi C (strain RKS4594) GN=SPC_2630 PE=3 SV=1 gi\|197241393, gi... - gi\|197263138\|ref\|ZP_03163212.1\| NAD(P)H:quinone oxidoreductase, type IV [Salmonella enterica subsp. ...	2.0E-49	[1..197]	[1..195]
gi\|12484052 - gi\|12484052\|gb\|AAG53945.1\|AF304462_1 quinone-oxidoreductase QR2 [Triphysaria versicolor]	2.0E-49	[2..197]	[3..199]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-49	[1..197]	[1..195]

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Predicted Domain #1

Region A:
Residues: [1-198]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRVAIIIYT LYGHVAATAE AEKKGIEAAG GSADIYQVEE TLSPEVVKAL GGAPKPDYPI  60
   61 ATQDTLTEYD AFLFGIPTRF GNFPAQWKAF WDRTGGLWAK GALHGKVAGC FVSTGTGGGN 120
  121 EATIMNSLST LAHHGIIFVP LGYKNVFAEL TNMDEVHGGS PWGAGTIAGS DGSRSPSALE 180
  181 LQVHEIQGKT FYETVAKF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.39794
Match:	1ag9A_
Description:	Flavodoxin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.32880196921974	bayes_pls_golite062009
binding	1.54529414520518	bayes_pls_golite062009
oxidoreductase activity	1.2698167260481	bayes_pls_golite062009
catalytic activity	0.275631658558537	bayes_pls_golite062009
protein binding	0.191220795572558	bayes_pls_golite062009
transcription factor binding	0.0852528568191628	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: